Annual Stanford Metabolic Health Center Symposium - Virtual Meeting

February 11, 2022

We have invited speakers from Stanford and beyond to talk about the latest scientific advances and developments in maternal and child health.

Topics will range across metabolomics, personalized medicine, nutrition, placenta accreta, and more!

Zoom link will be available several days before the event

Registration

Registration is free


Agenda

  • Virtual meeting via Zoom in Pacific Standard Time (PST)
  • 12:45pm: Zoom feed goes live
  • 1:00pm – 1:15pm: Welcome and overview of the Metabolic Health Center, Michael Snyder, PhD, Stanford University
  • 1:15pm – 1:45pm: Metabolomics from the fetus to adult: evolution or revolution?, Vassilios Fanos, MD, University of Cagliari, Italy
  • 1:45pm – 2:15pm: Human milk (oligosaccharides) at the intersection of maternal-infant health, Lars Bode, PhD, University of California San Diego
  • 2:15pm – 2:45pm: Does diet shape the microbiome?, Abigail Johnson, PhD, RDN, University of Minnesota
  • 2:45pm – 3:15pm: Break (30 mins)
  • 3:15pm – 3:45pm: Fatty acid status in the preterm infant: a case study in understanding neonatal metabolism and context specificity in bionutrient delivery, Camilia Martin, MD, MS, Harvard Medical School, Beth Israel Deaconess Medical Center
  • 3:45pm – 4:15pm: Metabolomics and placenta accreta spectrum: new directions to understand a dangerous pregnancy condition, Deirdre Lyell, MD, Stanford University
  • 4:15pm – 4:45pm: Precisely Practicing Medicine from 700 Trillion Points of Data, Atul Butte, MD, PhD, University of California San Francisco
  • 4:45pm – 5:00pm: Closing remarks

Event Speakers

Michael Snyder, PhD, Stanford University

Stanford W. Ascherman Professor of Genetics, Chair of Genetics, Director for Genomics and Precision Medicine, Director of the Stanford Metabolic Health Center

Snyder Lab was the first to perform a large-scale functional genomics project in any organism, and has developed many technologies in genomics and proteomics. These including the development of proteome chips, high resolution tiling arrays for the entire human genome, methods for global mapping of transcription factor binding sites (ChIP-chip now replaced by ChIP-seq), paired end sequencing for mapping of structural variation in eukaryotes, de novo genome sequencing of genomes using high throughput technologies and RNA-Seq. These technologies have been used for characterizing genomes, proteomes and regulatory networks.

Seminal findings from the Snyder laboratory include the discovery that much more of the human genome is transcribed and contains regulatory information than was previously appreciated, and a high diversity of transcription factor binding occurs both between and within species.

He has also combined different state-of-the-art "omics" technologies to perform the first longitudinal detailed integrative personal omics profile (iPOP) of person and used this to assess disease risk and monitor disease states for personalized medicine. Dr. Snyder is the cofounder of Personalis, SensOmics, Qbio @qbioinc, January, Filtricine, Mirvie, Protos, Protometrix (now part of Thermo-Fisher). Affomix (now part of Illumina). Dr. Snyder presently serves on the board of a number of companies.Dr Snyder is the author of the book: 'Genomics and Personalized Medicine: What Everyone Needs to Know'.

Vassilios Fanos, MD, University of Cagliari

Full Professor of Pediatrics and Director of the School of Specialty in Pediatrics, University of Cagliari, Italy. Director since 2003 of the Neonatal Intensive Care Unit, Azienda Ospedaliero Universitaria and University of Cagliari.

Immediate Past-President of the Union of the Middle-Eastern and Mediterranean Pediatric Societies (UMEMPS), President of SI-DOHaD (Italian Society of Developmental Origins of Health and Disease), Immediate Past-Treasurer of the European Association of Perinatal Medicine (EAPM), Member of the International Perinatal Collegium.

Editor-in-Chief of the Journal of Pediatric and Neonatal Individualized Medicine, peer-reviewed, open access (www.jpnim.com) official journal of many International Societies including Union of European Neonatal and Perinatal Societies (UENPS) and UMEMPS; indexed in SCOPUS and Web of Science. 

Consultant referee in more than 60 International Journals and board member in 10.

In the last 6 years with metabolomics he won 3 European Projects (1 FP7 European Project, 1 Marie Curie project, 1 LIFE project), 2 CCM Italian projects with 10,000.000 euros. Author of more than 600 original papers: 450 on PubMed, and more than 500 on Scopus. Referee for several International Agencies for funding.

Author of 32 books (8 in English). Author of more than 70 chapters of books (more than 30 in English). Speaker (including many Magistral Lectures) in more than 150 International Congresses in more than 40 Nations and hundreds of National Congresses.

Impact Factor > 1,200, Hirsh index:  57 (Google), 42 (Scopus) with > 13,000 citations (Google), > 8,000 (Scopus).

Camilia R. Martin, MD, MS, Harvard Medical School, Beth Israel Deaconess Medical Center

Associate Professor of Pediatrics, Harvard Medical School, Associate Director, NICU, Department of Neonatology, Director for Cross-Disciplinary Research Partnerships, Division of Translational Research, Beth Israel Deaconess Medical Center

Camilia (Cami) R. Martin M.D., M.S. is an Associate Professor of Pediatrics at Harvard Medical School, and the Associate Director of the Neonatal Intensive Care Unit and Director for Cross-Disciplinary Research Partnerships in the Division of Translational Research at Beth Israel Deaconess Medical Center (BIDMC), Boston, MA.

Dr. Martin received her M.D. from Weill Cornell Medical College and completed her internship and residency at Lurie/Children’s Memorial Hospital-Northwestern School of Medicine where she also served as Chief Pediatric Resident. Dr. Martin completed her fellowship in Perinatal-Neonatal Medicine at the Harvard Combined Program in Neonatology. During her fellowship training, she completed a Masters in Epidemiology at Harvard School of Public Health.

Dr. Martin’s research program spans basic to clinical translational research to study neonatal nutrition and its impact on health and disease in the preterm infant establishing, through these efforts, the Infant Health Research Program at BIDMC. Her research program is supported by broad based funding from the NIH, foundation, industry, philanthropy, and state-level programs. She participates in multi-site cohort studies and clinical trials serving as the Principal Investigator evaluating nutrition, growth, and long-term neurodevelopmental outcomes in the extremely preterm infant. Her current research focus is on lipids and fatty acid metabolism, postnatal intestinal adaptation including the microbiome, and the nutritional impact on organogenesis, development of immune defenses, and regulation of the inflammation. In addition, in collaboration with Dr. Sarbattama Sen at Brigham and Women’s Hospital (Boston, Harvard Medical School), Drs. Martin and Sen were recently awarded a $1.1M grant from the Massachusetts Life Sciences Center to develop a lactation laboratory to investigate breastmilk composition and its impact on maternal and infant health outcomes.

Abigail Johnson, PhD, RDN, University of Minnesota

Assistant Professor and Associate Director of the Nutrition Coordinating Center, Division of Epidemiology and Community Health, School of Public Health, University of Minnesota

 Abigail Johnson is an Assistant Professor and Registered Dietitian in the Division of Epidemiology & Community Health in the School of Public Health at the University of Minnesota. She is also Associate Director of the Nutrition Coordinating Center, which distributes and supports the Nutrition Data System for Research (NDSR). Dr. Johnson has diverse experiences in nutrition research, ranging from molecular biology and clinical nutrition to bioinformatics and public health. Her present research explores the relationships between diet and the human gut microbiome in health and disease – specifically in prediabetes and cancer survivorship. Dr. Johnson uses novel computational methods to integrate dietary data with other multi-omics data. Her research has demonstrated that daily changes in dietary intake and overall dietary patterns are reflected in shifts in microbial composition in humans and that diet-microbiome relationships are personalized.

Atul Butte, MD, PhD, University of California San Francisco

Priscilla Chan and Mark Zuckerberg Distinguished Professor of Pediatrics,  Bioengineering and Therapeutic Sciences, and Epidemiology and Biostatistics at UCSF, Director of the Bakar Computational Health Sciences Institute at UCSF, Chief Data Scientist, University of California Health System (UC Health)

Atul Butte, MD, PhD is the Priscilla Chan and Mark Zuckerberg Distinguished Professor and inaugural Director of the Bakar Computational Health Sciences Institute (bchsi.ucsf.edu) at the University of California, San Francisco (UCSF). Dr. Butte is also the Chief Data Scientist for the entire University of California Health System, the tenth largest by revenue in the United States, with 20 health professional schools, 6 medical schools, 6 academic health centers, 10 hospitals, and over 1000 care delivery sites. Dr. Butte has been continually funded by NIH for 20 years, is an inventor on 24 patents, and has authored over 200 publications, with research repeatedly featured in the New York Times, Wall Street Journal, and Wired Magazine. Dr. Butte was elected into the National Academy of Medicine in 2015, and in 2013, he was recognized by the Obama Administration as a White House Champion of Change in Open Science for promoting science through publicly available data. Dr. Butte is also a founder of three investor-backed data-driven companies: Personalis (IPO, 2019), providing medical genome sequencing services, Carmenta (acquired by Progenity, 2015), discovering diagnostics for pregnancy complications, and NuMedii, finding new uses for drugs through open molecular data. Dr. Butte trained in Computer Science at Brown University, worked as a software engineer at Apple and Microsoft, received his MD at Brown University, trained in Pediatrics and Pediatric Endocrinology at Children's Hospital Boston, then received his PhD from Harvard Medical School and MIT.

Lars Bode, PhD, University of California San Diego

Professor of Pediatrics (Bode Lab), Division of Neonatology and Division of Gastroenterology, Hepatology, and Nutrition, Director and Chair of Collaborative Human Milk Research, Larsson-Rosenquist Foundation Mother-Milk-Infant Center of Research Excellence (MOMI CORE), University of California, San Diego

Dr. Lars Bode is Professor of Pediatrics in the Division of Neonatology and the Division of Gastroenterology, Hepatology and Nutrition, the Larsson-Rosenquist Chair of Collaborative Human Milk Research, and the founding Director of the Mother-Milk-Infant Center of Research Excellence (MOMI CORE) at the University of California, San Diego.

Dr. Bode has been working on human milk oligosaccharides (HMOs) for over 20 years. He received both his Master of Science and PhD degree in Nutritional Sciences from the University Giessen, Germany, and completed a pre-doctoral fellowship at the Institute of Child Health, University College London, United Kingdom. Following a postdoctoral fellowship at the Sanford Burnham Prebys Medical Discovery Institute in La Jolla, California, Dr. Bode joined the University of California, San Diego, where he is leading a research program dedicated to investigating human milk oligosaccharide biosynthesis and functions with potential benefits for infant health and development.

Dr. Bode has published over 130 peer-reviewed articles on human milk oligosaccharides, including the 2012 review “Human Milk Oligosaccharides: Every Baby Needs a Sugar Mama”, which has become the most cited research article in the field of human milk oligosaccharides. In 2020, Dr. Bode ranked in the top 2% of most cited scientists in the world in the category “Nutrition and Dietetics”.

Deirdre Lyell, MD, Stanford University

Dunlevie Endowed Professor of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Associate Director of the Division of Maternal-Fetal Medicine and Obstetrics, Director of the Program in Placental Disorders. Medical Director for Labor and Delivery, Director for Maternal-Fetal Medicine Fellowship, Stanford University School of Medicine

Deirdre Lyell, MD is the Dunlevie Professor of Maternal-Fetal Medicine (MFM) in the Department of Obstetrics and Gynecology at Stanford University. She serves as the associate director of the division of MFM, director of perinatal epidemiology and population health in the Dunlevie MFM Center, associate medical director of the California Maternal Quality Care Collaborative, medical director of Labor and Delivery, and program director of the MFM fellowship.  In 2011 she received a Harman Faculty Scholar award to research placenta accreta spectrum and develop the Program in Placental Disorders at Stanford, for which she serves as medical director. Her research is aimed at understanding and improving maternal and perinatal outcomes particularly involving placenta accreta spectrum prediction, severe maternal morbidity, and anemia in pregnancy.

Event Sponsors

Thermo Fischer Scientific

Olink

Agilent

SciEx

Stanford Federal Credit Union

Center funding and partnerships







For any questions regarding the symposium, please reach out to Casandra Trowbridge at ctbridge@stanford.edu