Dante Capaldi, PhD


Dante Capaldi, PhD, simultaneously completed both PhD and MClSc degrees in Medical Biophysics at the University of Western Ontario, Canada, in 2018.  His PhD research, funded by the Natural Sciences and Engineering Research Council of Canada (NSERC), focused on the development and application of novel image acquisition and analysis methods to measure pulmonary ventilation in patients with lung disease.

Dante joined the Stanford University Medical Physics Residency in 2018 as a Medical Physics Resident and NSERC Postdoctoral Fellow.


  • Capaldi DPI, Nano TF, Zhang H, Skinner LB, Xing L.  Technical Note: Evaluation of Audiovisual Biofeedback Smartphone Application for Respiratory Monitoring in Radiation Oncology.  Medical Physics (2020).
  • Capaldi DPI*, Skinner LB*, Dubrowski P, Yu AS.  An Integrated Quality Assurance Phantom for Frameless Single-isocenter Multitarget Stereotactic Radiosurgery.  Physics in Medicine and Biology (2020); 65(11), 115006.(* Co-first Author)
  • Capaldi DPI, Hristov DH*, Kidd EA*.  Parametric Response Mapping of Co-registered Positron Emission Tomography and Dynamic Contrast Enhanced Computed Tomography to Identify Radio-resistant Sub-volumes in Locally Advanced Cervical Cancer.  International Journal of Radiation Oncology, Biology, Physics (2020); 107(4), 756-765. (* Co-senior Author)
  • MacNeil JL, Capaldi DPI, Westcott A, Eddy RL, Barker AL, McCormack DG, Kirby M, Parraga G.  Multi-Parametric Response Maps: Pulmonary Imaging Phenotypes of Chronic Obstructive Pulmonary Disease. Radiology (2020); 295(1), 227-236.
  • Wu Y, Ma Y, Capaldi DPI, Liu J, Zhao W, Du J, Xing L.  Incorporating Prior Knowledge via Volumetric Deep Residual Network to Optimize the Reconstruction of Sparsely Sampled MRI.  Magnetic Resonance Imaging(2020); 66, 93-103.
  • Westcott A, Capaldi DPI, McCormack DG, Fenster A, Parraga G.  Chronic Obstructive Pulmonary Disease: CT Texture Analysis and Machine Learning to Predict Pulmonary Ventilation.  Radiology (2019); 293(3), 676-684.(Editorialized)
  • Svenningsen S, Haider E, Boylan C, Mukherjee M, Eddy RL, Capaldi DPI, Parraga G, Nair P.  CT and functional MRI to evaluate airway mucus in severe asthma.  Chest (2019); 155(6), 1178-1189.
  • Guo F, Capaldi DPI, McCormack DG, Fenster A, Parraga G.  A Framework for Fourier-Decomposition Free-Breathing Pulmonary 1H MRI Ventilation Measurements.  Magnetic Resonance in Medicine (2019); 81(3), 2135-2146.
  • Westcott A, Capaldi DPI, Ouriadov A, McCormack DG, Parraga G.  Hyperpolarized 3He MRI Ventilatory Apparent Diffusion Coefficient of Alpha-1 Antitrypsin Deficiency.  Journal of Magnetic Resonance Imaging (2019); 49(1), 311.
  • Guo F, Capaldi DPI, Kirby M, Sheikh K, Svenningsen S, McCormack DG, Fenster A, Parraga G. "Development of a pulmonary imaging biomarker pipeline for phenotyping of chronic lung disease." Journal of Medical Imaging (2018); 5(2), 026002.
  • Capaldi DPI, Eddy RL, Svenningsen S, Guo F, Baxter JSH, McLeod AJ, Nair P, McCormack DG, Parraga G, CRRN Investigators. "Free-breathing Pulmonary MR Imaging to Quantify Regional Ventilation." Radiology (2018); 287(2), 693-704.
  • Adams CJ*, Capaldi DPI*, Di Cesare R, McCormack DG, Parraga G, CRRN Investigators. "On the potential role of MRI Biomarkers of COPD to Guide Bronchoscopic Lung Volume Reduction." Academic Radiology (2018); 25(2), 159-168. (*Co-first Author).
  • Capaldi DPI, Parraga G. "Through the Looking Glass and What was Found There: More Imaging Biomarkers of COPD." American Journal of Respiratory and Critical Care Medicine (2017); 196(11), 1364-1366.
  • Capaldi DPI, Sheikh K, Eddy RL, Guo F, Svenningsen S, Nair P, McCormack DG, Parraga G, CRRN Investigators. "Free-breathing Pulmonary MRI Ventilation Response to Bronchodilator and Provocation in Severe Asthma." Academic Radiology (2017); 24(10), 1268-1276.
  • Guo F, Svenningsen S, Kirby M, Capaldi DPI, Sheikh K, Fenster A, Parraga G. "Thoracic CT-MRI Co-Registration for Regional Pulmonary Structure-Function Measurements of Obstructive Lung Disease." Medical Physics (2017); 44(5), 1718-1733. (Cover of the Journal).
  • Dasgupta A, Kjarsgaard M, Capaldi DPI, Radford K, Aleman F, Boylan C, Altman LC, Wight T, Parraga G, O'Byrne PM, Nair P. "A pilot randomized clinical trial of mepolizumab in COPD with eosinophilic bronchitis." European Respiratory Journal (2017); 49(3), 1602486.
  • Sheikh K, Guo F, Capaldi DPI, Ouriadov A, Eddy RL, Svenningsen S, Parraga G, CRRN Investigators. "Ultra-short Echo Time Magnetic Resonance Imaging Biomarkers of Asthma." Journal of Magnetic Resonance Imaging (2017); 45(4), 1204-1215.
  • Guo F, Svenningsen S, Eddy RL, Capaldi DPI, Sheikh K, Fenster A, Parraga G. "Anatomical pulmonary magnetic resonance imaging segmentation for regional structure-function measurements of asthmas." Medical Physics (2016); 43(6), 2911-2926.
  • Capaldi DPI, Guo F, Parraga G. "Imaging How and Where We Breathe Oxygen: Another Big Short?" Journal of Thoracic Disease (2016); 8(3), E204.
  • Zha N, Pike D, Svenningsen S, Capaldi DPI, McCormack DG, Parraga G. "Second-Order Texture Measurements of 3He Ventilation MRI: Proof of Concept Evaluation of Asthma Bronchodilator Response." Academic Radiology (2016); 23(2), 176-185.
  • Capaldi DPI, Zha N, Guo F, Pike D, McCormack DG, Kirby M, Parraga G. "Pulmonary Imaging Biomarkers of Gas Trapping and Emphysema in COPD: 3He MR Imaging and CT Parametric Response Maps." Radiology (2016); 279(2), 597-608. (Cover of the Journal). 
  • Pike D, Kirby M, Eddy RL, Guo F, Capaldi DPI, Ouriadov A, McCormack DG, Parraga G. "Regional Heterogeneity of Chronic Obstructive Pulmonary Disease Phenotypes: Pulmonary 3He Magnetic Resonance Imaging and Computed Tomography." Journal of Chronic Obstructive Pulmonary Disease (2016); 13(5), 601-609.
  • Sheikh K*, Capaldi DPI*, Hoover DA, Palma DA, Yaremko BP, Parraga G. "Magnetic resonance imaging biomarkers of chronic obstructive pulmonary disease prior to radiation therapy for non-small cell lung cancer." European Journal of Radiology Open (2015); 2, 81-89. (*Co-first Author). 
  • Guo F, Yuan J, Rajchl M, Svenningsen S, Capaldi DPI, Sheikh K, Fenster A, Parraga G. "Globally Optimal Joint Segmentation of Three-dimensional Pulmonary 1H and Hyperpolarized 3He MRI with Spatial Consistence Prior." Medical Image Analysis (2015); 23(1), 43-55.
  • Capaldi DPI, Sheikh K, Guo F, Svenningsen S, Etemad-Rezai R, Coxson HO, Leipsic J, D.G. McCormack DG, Parraga G. "Free-breathing Pulmonary 1H and Hyperpolarized 3He MRI: Comparison in COPD and Bronchiectasis." Academic Radiology (2015); 22(3), 320-329.
  • Bhuiyan M, Malyarenko EV, Pantea MA, Capaldi DPI, Baylor AE, Maev RG. "Time-Frequency Analysis of Clinical Percussion Signals using Matrix Pencil Method." Journal of Electrical and Computer Engineering (2015). 
  • Hoover DA, Capaldi DPI, Sheikh K, Palma DA, Rodrigues GB, Dar R, Yu E, Dingle B, Landis M, Kocha W, Sanatani M, Vincent M, Younus J, Gaede S, Parraga G, Yaremko BP. "Functional lung avoidance for individualized radiotherapy (FLAIR): Study protocol for a randomized, double-blind clinical trial." BMC Cancer (2014); 14(1), 934.