Megan Clark, PhD

Biography

Megan Clark is from Manchester by-the-sea, MA. For undergrad, she completed a dual degree in physics and electrical engineering from Bates (2020) and Dartmouth (2021) Colleges, respectively. She then continued on for her PhD in biomedical engineering, specifically medical physics, from Dartmouth College where she graduated in spring of 2025. Her research focused on novel optical methods for dosimetry and oximetry of ultra-high dose rate radiation therapy. Megan joined the Stanford University Medical Physics Residency in July of 2025. In addition to here career and research interests, she loves to run, bike, and ski, make dinner with family and friends, and travel.

Megan joined the Stanford University Medical Physics Residency in 2025.

Publications

Published

Demidov, V.V., Clark, M.A., Streeter, S.S., Sottosanti, J.S., Gitajn, I.L., Elliott, J.T., 2023. High-energy open-fracture model with initial experience of fluorescence-guided bone perfusion assessment. J Orthop Res 41, 1040–1048. https://doi.org/10.1002/jor.25443

Clark, M., Ding, X., Zhao, L., Pogue, B., Gladstone, D., Rahman, M., Zhang, R., Bruza, P., 2023a. Ultra-fast, high spatial resolution single-pulse scintillation imaging of synchrocyclotron pencil beam scanning proton delivery. Phys Med Biol 68, 045016. https://doi.org/10.1088/1361-6560/acb753

Clark, M., Harms, J., Vasyltsiv, R., Sloop, A., Kozelka, J., Simon, B., Zhang, R., Gladstone, D., Bruza, P., 2023b. Quantitative real-time measurements of dose and dose rate in UHDR proton pencil beams via scintillation imaging system. https://doi.org/10.48550/ARXIV.2312.14841

Dai, T., Sloop, A.M., Rahman, M.R., Sunnerberg, J.P., Clark, M.A., Young, R., Adamczyk, S., Von Voigts‐Rhetz, P., Patane, C., Turk, M., Jarvis, L., Pogue, B.W., Gladstone, D.J., Bruza, P., Zhang, R., 2024a. First Monte Carlo beam model for ultra‐high dose rate radiotherapy with a compact electron LINAC. Medical Physics mp.17031. https://doi.org/10.1002/mp.17031

Dai, T., Sloop, A.M., Schönfeld, A., Flatten, V., Kozelka, J., Hildreth, J., Bill, S., Sunnerberg, J.P., Clark, M.A., Jarvis, L., Pogue, B.W., Bruza, P., Gladstone, D.J., Zhang, R., 2024b. Electron beam response corrections for an ultra‐high‐dose‐rate capable diode dosimeter. Medical Physics 51, 5738–5745. https://doi.org/10.1002/mp.17121

Petusseau, A.F., Clark, M., Bruza, P., Gladstone, D., Pogue, B.W., 2024. Intracellular oxygen transient quantification in vivo during Ultra-High Dose Rate (UHDR) FLASH radiotherapy. International Journal of Radiation Oncology*Biology*Physics S0360301624006102. https://doi.org/10.1016/j.ijrobp.2024.04.068

Vasyltsiv, R., Rahman, M., Harms, J., Clark, M., Gladstone, D.J., Pogue, B.W., Zhang, R., Bruza, P., 2024. Imaging and characterization of optical emission from ex vivo tissue during conventional and UHDR PBS proton therapy. Phys. Med. Biol. 69, 075011. https://doi.org/10.1088/1361-6560/ad2ee6

Tavakkoli, A.D., Clark, M.A., Kheirollah, A., Sloop, A.M., Soderholm, H.E., Daniel, N.J., Petusseau, A.F., Huang, Y.H., Thomas, C.R., Jarvis, L.A., Zhang, R., Pogue, B.W., Gladstone, D.J., Hoopes, P.J., 2023. Anesthetic oxygen use and sex are critical factors in the FLASH sparing effect. https://doi.org/10.1101/2023.11.04.565626

Clark, M , Xiao, Z, Sloop, A, Zhang, Y, Lee, E, Vasyltsiv, R, Gladstone, D, Zhang, R, Bruza, P, Mascia, A. First Retrospective QA of FAST-01 Clinical Treatment Fields Using High-Speed Quantitative Scintillation Imaging. Int J Radiat Oncol Biol Phys. 2025 May 1;122(1):194-198. doi: 10.1016/j.ijrobp.2024.12.005.

Clark, M, Daniel, N, Bruza, P, Zhang, R, Jarvis, L, Hoopes, P. J., Gladstone,D. Imaging System for Real-time Pulse-by-Pulse In Vivo Surface Dosimetry of UHDR Electron Beams. Med Phys. 2025; 52: 5026–5031. https://doi.org/10.1002/mp.17784

Under Review

Megan Clark, Armin Tavakkoli, et al. Scientific Reports. Dynamic oxygen assessment techniques enable determination of anesthesia’s impact on tissue.

Awards and Honors

  • Dartmouth Engineering Prize for Graduate Research Excellence, Dartmouth College (June 2025)
  • Best-in-Physics, ASTRO Annual Meeting (Fall 2024)
  • Best-in-Physics, AAPM Annual Meeting (Summer 2024)
  • Best Abstract Awardee, FRPT Annual Meeting (Winter 2023)
  • 1st Place, Early-Career Investigator Symposium, NEAAPM Annual Meeting (Spring 2023)
  • Dartmouth Cancer Center Travel Award Grant Awardee, Dartmouth Cancer Center (Winter 2023)
  • Thomas Kelvin Burnap Biomedical Engineering Fellow Award, Dartmouth College (Fall 2021)
  • Brieanna S. Weinstein Engineering Design Prize Award, Dartmouth College (June 2021)
  • Phi Beta Kappa, Bates College (May 2020)
  • Magna Cum Laude, Bates College (May 2020)
  • NESCAC Cross Country and Track All-Academic Award (2017-2020)
  • NESCAC Cross Country Sportsmanship Award (Fall 2017)
  • Deans List, Bates College (Fall 2016- Spring 2020)
  • President’s Volunteer Service Award (2016)
  • Manchester-by-the-Sea Selectmen’s Citizenship Award (2016)

Other

Patents

Approved

  • Patent No. 10690821: Methods of producing slanted gratings
  • Patent No. 12036421: Systems and methods for FLASH therapy

Pending

  • Patent Application No. 63444926: Transrectal Probe for Scintillation Imaging as a Method of Real Time Dosimetry of High-DoseRate Brachytherapy

Provisional

  • NG Tube Placement Verification Using Light for Visual Confirmation (Expired)

 

Certifications

  • American Board of Radiology, Part 1 (August 2023)
  • National Scient Foundation Regional I-Corps (Winter 2024)