Uytengsu-Hamilton 22q11 Neuropsychiatry Research Awards

The Stanford Maternal and Child Health Research Institute (MCHRI) Uytengsu-Hamilton 22q11 Neuropsychiatry Research Program aims to promote innovative, transdisciplinary research to improve the neurocognitive outcomes and behavioral symptoms of 22q11.2 Deletion Syndrome with immediate (within 5 years) and long-term impact.

22q11.2 Deletion Syndrome (22q11.2DS) is a genetic disorder caused by a microdeletion on chromosome 22. The disorder is associated with a broad spectrum of symptoms including immune dysfunction, congenital heart disease, palatal abnormalities and endocrine dysfunction. Children and young people with 22q11.2DS are at increased risk for developmental delay, learning disabilities, neurodevelopmental and neuropsychiatric disorders including schizophrenia, autism spectrum disorders, attention-deficit / hyperactivity disorder (ADHD), and anxiety.

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The program will provide up to 2 years of seed funding that could best (or only) be performed by researchers from different disciplines. This program will fund innovative research projects in the following categories: 

Category A:  Research at Stanford University (up to 4 awards)
Category B:  Research external to Stanford University (up to 2 awards)

The program will support a wide range of scientific approaches with the potential to advance our understanding of 22q11.2DS and its neuropsychiatric manifestations in the following areas:

  1. Basic and clinical translational research relevant to neurodevelopment and neuropsychiatry in 22q11.2DS, including but not limited to: neuroscience, genetics and genomics, psychiatry, neuroimmunology, metabolism, gut-brain axis, data science, bioinformatics or computational methodologies utilizing existing data, and novel therapeutics (up to a maximum of $150K/year)

  2. Basic and clinical translational research addressing the wider spectrum of symptoms in 22q11.2DS, including but not limited to: immunology, cardiology, endocrinology, developmental biology, genetics and genomics, and novel therapeutics (up to a maximum of $150K/year; Category A – Stanford applicants only)      

Key Dates

Action Date
Letter of Intent Deadline October 17, 2022 @ 11:59 pm (Pacific Time Zone) 
Full Proposal (by invitation) Deadline

January 16, 2023 @ 11:59 pm (Pacific Time Zone)

Notification of Awards
Week of February 20, 2023
Award Start Date March 1, 2023

Applicants should submit a 1-2 page letter of intent at the Online Submission LinkCategory A applicants: You do not need to submit your LOI via your RPM. 

Project start date is March 1, 2023.  The performance period is for no longer than 2 years.

Forms for Applicants

Funding Amount

Total award is up to $150,000 / year for up to two years. Applicants may request support for personnel (undergraduate, graduate, or postdoctoral students, research assistants, associates, or faculty) and research-related expenses.

Funds cannot be used for student tuition or fees, computer equipment, office supplies, ITCC communications, journal subscriptions, membership dues, poster presentations, abstract submissions, or any indirect research costs.

General Eligibility

Category A: Eligible applicants must be Stanford faculty holding Clinician Educator (CE), University Tenure Line (UTL), Research (NTL-Research), or University Medical Line (UML) positions for the duration of the award.  Visiting scholars are not eligible to serve as PI; they may serve as collaborators or co-investigators. Applications may include co-investigators from other research organizations. Current or previous award holders of the  Stanford MCHRI 22q11.2DS Neuropsychiatry Research Program are eligible to apply, if the end date of their current award falls before March 1, 2023.

Category B: Eligible applicants must be faculty members at an eligible organization and have a contract of employment for the duration of the award. Eligible organizations include US and non-US, public and private higher education institutions and academic medical centers. US research organizations are required to hold 501(c)(3) tax exempt status, and international research organizations must be able to demonstrate 501(c)(3) equivalency, if awarded. Applicants not funded in previous funding cycles may resubmit proposals. Please contact the Program Director with any questions relating to eligibility.

Awards

Contact

Please contact Rachael Panizzo, PhD, Program Director at rpanizzo@stanford.edu or 650-721-6720 with any questions.