Publications CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism Towards an ion-channel-centric approach to ultrasound neuromodulation Novel CLC-Kb pore mutation associated with defective glycosylation and renal tubulopathy Development and validation of a potent and specific inhibitor for the CLC-2 chloride channel Development and validation of a potent and specific inhibitor for the CLC-2 chloride channel An international gathering of physiologists in Valparaiso, Chile Spike-frequency dependent inhibition and potentiation of neural activity by ultrasound Expanding the membrane-protein NMR toolkit Spike frequency-dependent inhibition and excitation of neural activity by high-frequency ultrasound Dynamical model of the CLC-2 ion channel reveals conformational changes associated with selectivity-filter gating LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP Special Issue: Molecular Biophysics of Membranes and Membrane Proteins Preface A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the Cl-/H+ transport cycle Activation of Piezo1 but Not NaV1.2 Channels by Ultrasound at 43 MHz A selective class of inhibitors for the CLC-Ka chloride ion channel CLC Chloride/Proton Transporters Protein ligands for studying ion channel proteins Revealing an outward-facing open conformational state in a CLC Cl-/H+ exchange transporter An Outward-Facing Open Conformational State in a CLC Transporter Molecular Basis for Differential Anion Binding and Proton Coupling in the Cl(-)/H(+) Exchanger ClC-ec1 C-13 NMR detects conformational change in the 100-kD membrane transporter ClC-ec1 Monitoring Substrate-Driven Structural Changes in a CLC Chloride-Proton Antiporter with Double Electron-Electron Resonance Spectroscopy Water access points and hydration pathways in CLC H+/Cl- transporters Novel diuretic targets Dynamic Response of Model Lipid Membranes to Ultrasonic Radiation Force Dynamic response of model lipid membranes to ultrasonic radiation force Monitoring Substrate-driven Structural Changes in a CLC Chloride-Proton Antiporter with Double Electron-Electron Resonance Spectroscopy CLC Transporters: The Search for Conformational Change Structural investigations of ClC-ec1, a large integral membrane protein, using solution-state NMR and nanodisc technology Ultrasound-Induced Currents in Planar Lipid Blayers: Origins and Potential Physiological Significance A Designed Inhibitor of a CLC Antiporter Blocks Function through a Unique Binding Mode Characterization of a Novel CLC-ec1 Inhibitor Biochemistry to the Rescue: A CIC-2 Auxiliary Subunit Provides a Tangible Link to Leukodystrophy Monitoring Substrate-Driven Conformational Changes of ClC-ec1 by [Methyl-13C] Methionine NMR Proton-coupled gating in chloride channels Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR Discovery of potent CLC chloride channel inhibitors Ion Channel Targets - Select Biosciences' Fourth Annual Conference A Cytoplasmic Domain Mutation in ClC-Kb Affects Long-Distance Communication Across the Membrane The ClC-0 chloride channel is a 'broken' Cl-/H+ antiporter Thinking outside the crystal Complementary approaches for examining transporter conformational change Inhibition of CLC-ec1 by DIDS hydrolysis products The CLC 'chloride channel' family: revelations from prokaryotes The mechanism of fast-gate opening in ClC-0 The role of a conserved lysine in chloride- and voltage-dependent ClC-0 fast gating Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule Side-dependent inhibition of a prokaryotic CIC by DIDS The poststructural festivities begin Projection structure of a CIC-type chloride channel at 6.5 angstrom resolution CIC chloride channels A decade of CLC chloride channels: Structure, mechanism, and many unsettled questions High-level expression, functional reconstitution, and quaternary structure of a prokaryotic ClC-type chloride channel Formation of CLC-0 chloride channels from separated transmembrane and cytoplasmic domains IMPORT OF A MITOCHONDRIAL PRESEQUENCE INTO P-DENITRIFICANS - INSIGHT INTO THE EVOLUTION OF PROTEIN-TRANSPORT IMPORT OF A MITOCHONDRIAL PRESEQUENCE INTO PROTEIN-FREE PHOSPHOLIPID-VESICLES
