News

STAT celebrates the unheralded heroes of science and medicine, poring over hundreds of nominations from across North America in search for the next generation of scientific superstars.

ACGT has awarded a grant to Crystal Mackall to support the development of a remote-controllable CAR T-cell therapy for solid tumors.

SCI News highlights the recently published work by Sean Yamada-Hunter, Johanna Theruvath, and team illuminating the relationship between adoptively transferred T cells and macrophages and how two immunotherapies may work together to increase their tumor-fighting capabilities.

SCI News highlights recently published work from Crystal Mackall's lab at Stanford and Evan Weber's lab at the Children’s Hospital of Philadelphia (CHOP). Alexander Doan, Katherine Mueller, Andy Chen, and team identified a protein, FOXO1, that improves the survival and function of CAR-T cells, which may lead to more effective CAR-T cell therapies and could potentially expand its use in difficult-to-treat cancers.

SCI News highlights two recently published papers from the Mackall lab: work by Tara Murty, Sneha Ramakrishna, and team on immune determinants of CAR-T cell therapy & work by Dorota Klysz and team on better nutrition for stronger CAR-T cells.

Stanford News highlights the work by Victor Tieu and team, which found that an RNA-targeting CRISPR platform could tune immune cell metabolism without permanent genetic changes, potentially unveiling a relatively low-risk way to upgrade existing cell therapies for cancer.

Nature News highlights recently published work by Victor Tieu and team describing a system that edits RNA rather than DNA, which can give new life to exhausted CAR T cells.

In this episode of From Bench to Fireside, Crystal Mackall, MD, Center Director for the PICI (Parker Institute for Cancer Immunotherapy) Center at Stanford Medicine, talks through what led to her contributions to cancer immunotherapy, including her point of view on tackling challenging problems like pediatric cancers.

The Academy of Immuno-Oncology was established by SITC to honor individuals who have launched the field of cancer immunotherapy into the breakthrough cancer treatment it is today and bring together the brightest minds in the field to continue to advance SITC, the field, and the next generation of immuno-oncologists.

To promote growth and achievement amongst young investigators in the field of cancer biologics and to recognize excellence in the oral abstract and poster presentations submitted to the Society for Immunotherapy of Cancer's (SITC) Annual Meeting, SITC offers the Young Investigator Awards.