Meet Our Team
Stanley Yung C. Liu, MD, DDS, FACS
Associate Professor of Otolaryngology, and by courtesy, to the Division of Plastic & Reconstructive Surgery
Stanford University School of Medicine
Director, Sleep Surgery Fellowship
- Invited professorships to 5 Universities
- Keynote talks at the American, Chinese, Spanish Sleep Medicine Conferences
- Keynote talks at international ENT and Maxillofacial Conferences
- Chair to 7 World Sleep Symposiums
- Grand Rounds Speaker to 9 Universities
- 80 original scientific texts, 22 book chapters
My introduction to sleep came by way of the iconic Sleep and Dreams undergraduate course at Stanford by the late Dr. Bill Dement. Surgically, I owe my mentors who are also pioneers of our field in Dr. Nelson Powell and Dr. Robert Riley. The Powell and Riley Stanford sleep surgery approach has served as a foundation to our clinical approach. Since starting as a faculty member at Stanford after my fellowship in 2014, I have continued to update the approach to patients with sleep-disordered breathing.
Surgery for sleep apnea should aim to restore form, followed by re-training of function. The ideal facial and airway form during sleep would promote nasal breathing and upper airway dilator muscle function, both of which work best with optimal maxillofacial skeletal position. In combination with preservation nasal and soft palatal surgery, and upper airway stimulation, we are more equipped than ever to restore healthy breathing during sleep.
Ahmed AlSayed, MD
Vikram Padhye, MD
Pien Bosschieter was born in the Netherlands and studied Medicine at the University of Groningen, where she obtained her M.D. degree. In 2019 she started research under the supervision of Prof. Dr. N. de Vries, Prof. Dr. F. Lobbezoo en Dr. M.J.L. Ravesloot at the Ear, Nose, Throat department of OLVG, and obtained her PhD degree in June 2022. Simultaneously she worked as a resident at the same department and conducted over 1500 drug-induced sleep endoscopies focusing on improving OSA-patient care.
In September she will take the exam of the European Sleep Research Society (ESRS) to obtain the title of certified somnologist.
Pien is excited to have joined the Sanford Sleep Surgery division as a post-doctoral fellow. In this role she will be continuing her line of research evaluating pre and post treatement Pcrit measurements during DISE.
Bosschieter PFN, Schoustra E, de Vries N, Steinbusch MJL, Kasius KM, Ravesloot MJL. Daytime polysomnography to perform titration for upper airway stimulation in patients with obstructive sleep apnea. Sleep Breath. 2021 Jul 28. doi: 10.1007/s11325-021-02441-w. Epub ahead of print. PMID: 34319499.
Bosschieter PFN, Vonk PE, de Vries N, Ravesloot MJL. Position-dependent obstructive sleep apnea and its influence on treatment success of mandibular advancement devices. Sleep Breath. 2021 Oct 28. doi: 10.1007/s11325-021-02488-9. Epub ahead of print. PMID: 34709563.Zhou N, Ho JPTF, de Vries N,
Bosschieter PFN, Vonk PE, de Vries N. The predictive value of drug-induced sleep endoscopy for treatment success with a mandibular advancement device or positional therapy for patients with obstructive sleep apnea. Sleep Breath. 2021 Oct 1. doi: 10.1007/s11325-021-02501-1. Epub ahead of print. PMID: 34596877.
Reijers SNH, Nijland LMG, Bosschieter PFN, de Raaff CAL, Ravesloot MJL, van Veen RN, de Castro SMM, de Vries N. The effect of postoperative CPAP use on anastomotic and staple line leakage after bariatric surgery. Sleep Breath. 2021 Jun;25(2):1037-1043. doi: 10.1007/s11325-020-02199-7. Epub 2020 Sep 28. PMID: 32986151.
Bardi F, Bosschieter PFN, Verheij J, Go A, Haak M, Bekker M, Sikkel E, Coumans A, Pajkrt E, Bilardo C. Is there still a role for nuchal translucency measurement in the changing paradigm of first trimester screening? Prenat Diagn. 2020 Jan;40(2):197-205. doi: 10.1002/pd.5590. Epub 2019 Nov 27. PMID: 31697852; PMCID: PMC7027496.
Zhou N, Ho JTF, de Vries N, Bosschieter PFN, Ravesloot MJL, de Lange J. Evaluation of drug-induced sleep endoscopy as a tool for selecting patients with obstructive sleep apnea for maxillomandibular advancement. J Clin Sleep Med. 2021 Dec 9. doi: 10.5664/jcsm.9802. Epub ahead of print. PMID: 34877928.
Huang Z, Aarab G, Ravesloot MJL, Zhou N, Bosschieter PFN, van Selms MKA, den Haan C, de Vries N, Lobbezoo F, Hilgevoord AAJ. Prediction of the obstruction sites in the upper airway in sleep-disordered breathing based on snoring sound parameters: a systematic review. Sleep Med. 2021 Oct 21;88:116-133. doi: 10.1016/j.sleep.2021.10.015. Epub ahead of print. PMID: 34749271.
Bosschieter PFN, Vries N, Mehra R, Manchanda S, Padhya TA, Vanderveken OM, Ravesloot MJL; ADHERE Registry Investigators. Similar effect of hypoglossal nerve stimulation for obstructive sleep apnea in five disease severity categories. J Clin Sleep Med. 2022 Mar 3. doi: 10.5664/jcsm.9956. Epub ahead of print. PMID: 35236551.
Huang Z, Bosschieter PFN, Aarab G, van Selms MKA, Vanhommerig JW, Hilgevoord AAJ, Lobbezoo F, Vries N. Predicting upper airway collapse sites found in drug-induced sleep endoscopy from clinical data and snoring sounds in obstructive sleep apnea patients: a prospective clinical study. J Clin Sleep Med. 2022 Apr 26. doi: 10.5664/jcsm.9998. Epub ahead of print. PMID: 35459443.
Uniken Venema JAM, Bosschieter PFN, Vonk PE, Plooij J, Lobbezoo F, Hoekema A, de Vries N. Dental parameters predicting DISE and PSG outcome. Submitted to Sleep and breathing.
Bosschieter PFN, Uniken Venema JAM, Vonk PE, Plooij J, Lobbezoo F, Hoekema A, de Vries N. The comparison of an interim and a custom-made mandibular advancement device to treat obstructive sleep apnea. J Clin Sleep Med. 2022 May 9. Doi: 10.5664/jcsm10058
Bosschieter PFN, Uniken Venema JAM, Vonk PE, Plooij J, Lobbezoo F, Hoekema A, de Vries N. An thermoplastic oral appliance as a screening tool during DISE to predict treatment success with a mandibular advancement device for obstructive sleep apnea. Submitted to Sleep and breathing.
Dreuning KMA, Haverman L, Bosschieter PFN, van Looij MAJ, van Heurn ELW, Derikx JPM. Age-specific and family-centered approach to prepare children at home for day-care surgery. Submitted to journal of pediatric surgery.
Leentjens M, Bosschieter PFN, Al-Terki A, Raaff de CAL, Vries de CEE, Abu-Farha M, Hammad M, Thanaraj TA, Al-Khairi I, Cherian P, Channanath A, Wagensveld van BA, Abubaker J and N de Vries. The predictive value of the biomarker ANGPTL5 in diagnosing obstructive sleep apnea in bariatric patients. Submitted to Sleep and breathing.
Alterki A, Abu-Farha2 M, Leentjens M, Bosschieter PFN, de Raaff CAL, de Vries DEE, Al Shawaf E, Thanaraj TA, Al-Khairi I, Cherian P, Channanath A, Kavalakatt S, van Wagensveld BA, Abubaker J, de Vries N. Increased plasma ANGPTL7 levels with increased obstructive sleep apnea severity. Submitted.
Book Chapters and non-peer-reviewed publications
Bosschieter PFN, van Maanen JP Vijf jaar tongzenuwstimulatie. Apneumagazine nr. 3 - 2020
Bosschieter PFN, Schoustra E, de Vries N, Steinbusch MJL, Kasius KM, Ravesloot MJL. Daytime Polysomnography to perform titration for Upper Airway Stimulation in patients with Obstructive Sleep Apnea. In: Heiser C, de Vries N (eds), Upper Airway Stimulation in Obstructive Sleep Apnea: Best Practices in Evaluation and Surgical Management, Springer New York, in press.
Vries N, Piccin O, Vanderveken O, Vicini C. (Eds). Drug-induced sleep Endoscopy. Instructie-video’s; Bosschieter PFN, Thieme.
Bosschieter PFN, de Vries N. Positional OSA. In: S.E. Kountakis, T.M. Onerci. Rhinologic and sleep apnea surgical techniques, second edition. Springer, in press.
Bosschieter PFN, de Vries N. Risks of general anesthesia in OSA patients. In: S.E. Kountakis, T.M. Onerci. Rhinologic and sleep apnea surgical techniques second edition. Springer, in press.
Bosschieter PFN, de Vries N. DISE. In: S.E. Kountakis, T.M. Onerci. Rhinologic and sleep apnea surgical techniques second edition. Springer, in press.
Boekhoofdstuk ‘’positional therapy’’ International Consensus Statement on Obstructive Sleep Apnea (ICS-OSA). Goldberg et al, in press.
Bosschieter PFN, de Vries N. Patient selection. In: Heiser C, de Vries N. (eds), Upper Airway Stimulation in Obstructive Sleep Apnea: Best Practices in Evaluation and Surgical Management, Springer New York, in press.
Ashlee Hong, DDS
Nazlie Taheri, DDS
Pi-Jun Lee, MD
Plastics & Reconstructive Surgery Assistant Professor, NCKU, Taiwan
Myeong Sang Yu, MD
ENT Associate Professor, Ulsan Medical University, Seoul, S. Korea
Sasikarn Poomkonsarn, MD
ENT Assistant Professor, Raj Hospital, Bangkok, Thailand