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Laboratory of Signaling Dynamics

Principal Investigator

Michael Z. Lin, MD, PhD

Michael Z. Lin received an A.B. summa cum laude in Biochemistry from Harvard, an M.D. from UCLA, and a Ph.D. from Harvard Medical School. After training in biochemistry and neurobiology as a PhD student with Michael Greenberg at Harvard Medical School, Dr. Lin performed postdoctoral research in fluorescent protein engineering with Chemistry Nobel Laureate Roger Y. Tsien at UCSD. Dr. Lin is a recipient of a Burroughs Wellcome Career Award for Medical Scientists, a Rita Allen Scholar Award, a Damon Runyon-Rachleff Innovation Award, and a NIH Pioneer Award.

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The Lin Lab applies biochemical knowledge and engineering principles to the development of protein-based tools for molecular imaging, optogenetic studies, and gene therapy. Topics of investigation include fluorescent protein structures and biophysics, fluorescentprotein-based biosensors, spatiotemporal analysis of protein translation pathways, chemical control of protein translation, and light-responsive proteins. 


We've moved! As of January 15, 2020, our office and lab are located in the brand new ChemH-Neuroscience Complex at 290 Jane Stanford Way. This new research complex serves as the home base for two interdisciplinary life sciences institutes at Stanford University: Stanford ChEM-H and the Wu Tsai Neurosciences Institute. We are excited to be a part of this innovative work space!

Our paper describing Ultrafast Two-Photon Imaging of a High-Gain Voltage Indicator in Awake Behaving Mice is out in Cell: Congratulations to Mariya, Benjamin, Dongqing and Stephen for their collaboration on this fine research.