Members of the Life Science Alliance
At the core of the Alliance are our Members - faculty from EMBL and the Stanford University School of Medicine. Their combined expertise spans a broad spectrum of life science research from structural biology and bioinformatics, to chemistry, imaging and genomics. They are committed to the exchange of information to solve complex biomedical challenges together
View their research interests and collaborations below.
Join us!
We are always open to accepting new members from EMBL and Stanford University. If our projects or interests match yours, contact us - we would love to hear from you.
Monther Abu-Remaileh
Projects:
Networks of subcellular compartments in health and disease (with Sinem Saka)
Mitochondrial thermal proteome profiling for the study of oncometabolites interactome (with Mikhail Savitski)
Alexander Aulehla
Projects:
Connecting organizational scales from the bottom-up to investigate emergence in embryonic pattern formation (with James Ferrell & Anna Erzberger)
Theodore Alexandrov
Projects:
Physiological regulation of metabolism in single cells (with Katrin Svensson)
Maria Bernabeu
Project:
Functional characterization of host determinants of malaria infection (with Elizabeth Egan)
Ami Bhatt
Project:
Developing global interaction networks of microbiome-encoded genes (with Peer Bork)
Vivek Bhalla
Research Interests:
Using and developing innovative methodologies to discover novel molecular mechanisms and therapies for kidney health.
Matthieu Boulard
Research Interests:
Molecular basis of chromatin-based silencing and cellular readout of cytosine methylation.
Peer Bork
Project:
Developing global interaction networks of microbiome-encoded genes (with Ami Bhatt)
Wah Chiu
Research Interests:
The development of cryo-EM methodology to determine 3D cellular structures. We also work on the EMDataResource which is an open access database for 3D EM for developing software, data standards and validation methods.
Isidro Cortes Ciriano
Project:
Quantifying tumour evolution and fitness landscapes (with Christina Curtis)
Christina Curtis
Project:
Quantifying tumour evolution and fitness landscapes (with Isidro Cortés-Ciriano)
Martha Cyert
Research Interests:
Discovering new calcium-dependent signaling pathways in humans that are regulated by the calcineurin protein phosphatase
Claire Deo
Research Interests:
Developing novel molecular tools for advanced biological imaging by combining synthetic chemistry and protein engineering
Gautam Dey
Project:
Cell cycle adaptation to aneuploidy: How do cells adapt to carrying an extra chromosome? (with Gavin Sherlock)
José Dinneny
Research Interests:
Understanding the response of roots to water-limiting conditions and across different organizational scales from the individual cell type to the whole plant.
Olivier Duss
Research Interests:
Assembly mechanisms and function of protein-RNA complexes at the single-molecule level
Elizabeth Egan
Project:
Functional characterization of host determinants of malaria infection (with Maria Bernabeu)
Jan Ellenberg
Project:
Advancing imaging technology (with Tobias Meyer)
Anna Erzberger
Project:
Connecting organizational scales from the bottom-up to investigate emergence in embryonic pattern formation (with Alexander Aulehla & James Ferrell)
Dean Felsher
Research Interests:
How oncogenes initiate and sustain tumorigenesis including: how oncogene activation causes tumor regression, and how tumors escape dependence on oncogenes.
James Ferrell
Projects:
Connecting organizational scales from the bottom-up to investigate emergence in embryonic pattern formation (with Alexaander Aulehla & Anna Erzberger)
Judith Frydman
Research Intersets:
Understanding protein folding including: function and mechanism of chaperones, chaperone networks, ribosome biogenesis, co-translational folding, protein folding homeostasis, misfolding and aggregation disease.
Margaret Fuller
Research Interests:
Regulation of self-renewal, proliferation and differentiation in adult stem cell lineages: including regulation of cell type specific transcription programs, cell-cell communication, and the role of differential mRNA processing and translational control in progression from one cell state to the next.
Eileen Furlong
Research Interests:
Genome regulation and topology during embryonic development including: chromatin topology, chromatin remodelling during cell fate decisions, variation and plasticity in regulatory networks, developmental enhancers, and single cell genomics.
Andrew Gentles
Research Interests:
Computational approaches to understand biological systems using genomic and proteomic data across populations. Most of our work is in cancer and neurodegenerative disease, but we love to hear about any interesting questions!
Miriam Goodman
Research Interests:
Deciphering the molecular events responsible for touch, pain, and position sensation in C. elegans.
Jamie Hackett
Research Interests:
Understanding the mechanistic interplay between genome regulation, chromatin and environmental cues (microbiome), with emphasis on intergenerational effects
Matthias Hentze
Research Interests:
Using biochemical and systems-level approaches to investigate the connections between gene expression and cell metabolism, and their roles in human disease.
Ruth Huettenhain
(incoming faculty at Stanford, 2023)
Research interests:
How G protein-coupled receptors decode extracellular cues into dynamic and context-specific cellular signaling networks to elicit diverse physiologic responses
Maya Kasowski
Using scMulti-omics to probe clinical outcome of child leukemia treatment (with Judith Zaugg)
Teri Klein
Project:
Pharmacogenomic network analyses in diverse population datasets (with Ellie McDonagh)
Brian Kobilka
Research interests:
Characterizing the structure and mechanism of G-Protein Coupled Receptors (GPCRs).
Anshul Kundaje
Projects:
Integrative machine learning to decipher genome function (with Oliver Stegle)
Transcription Factor cooperativity atlas (with Arnaud Krebs)
Jin Billy Li
Research Interests:
RNA editing. We are interested in ADAR-mediated RNA editing, for both its biological function in dsRNA-mediated innate immunity and its utility as a tool for transcriptome engineering.
Julia Mahamid
Research Interests:
We employ state-of-the-art cellular cryo-electron tomography to study phase-separated assemblies in cell biology and to advance our understanding of the molecular organization of the cytoplasm.
José Márquez
Research Interest:
We develop methods and software for high-throughput, automated crystallography and use them to study the structure of sensing and signalling molecules.
Ellie McDonagh
Project: Pharmacogenomic network analyses in diverse population datasets (with Teri Klein)
Tobias Meyer
Projects:
Advancing imaging technology (with Jan Ellenberg)
Stephen Montgomery
Project:
Mapping the effects of genetic variants from genes to cells to disease (with Oliver Stegle)
Robert Prevedel
Research Interests:
Advanced optical techniques for deep tissue microscopy. In particular, we work in the fields of multi-photon microscopy, active wave-front shaping, photo-acoustics as well as computational imaging. Looking for collaboration in cell & developmental biology and neuroscience, where our novel imaging approaches can give new insights.
Marlene Rabinovitch
Project:
Multiomics for pulmonary hypertension (with Judith Zaugg)
Georgia Rapti
Research Interests:
Dissecting the cellular and molecular mechanisms of nervous system assembly and the underlying glia–neuron crosstalk, using advanced genetics, genomics and live imaging approaches.
Kacper Rogala
Research Interest:
Mechanistic understanding of how cells control metabolism in response to nutrients and growth factors, and ways to modulate these activities with chemical probes — for the benefit of patients.
Santiago Rompani
Research Interests:
Studying the function of visual circuits using functional imaging, genetics, virology and behavioural assays.
Mikhail Savitski
Project:
Mitochondrial thermal proteome profiling for the study of oncometabolites interactome (with Monther Abu-Remaileh)
Sinem Saka
Project:
Networks of subcellular compartments and subcellular organization in health and disease (with Monther Abu-Remaileh)
Gavin Sherlock
Project:
Cell cycle adaptation to aneuploidy: How do cells adapt to carrying an extra chromosome? (with Gautam Dey)
Yiorgo Skiniotis
Research Interests:
Developing a mechanistic understanding of signal translation at the cell membrane using structural biology, biochemistry and simulation methods
Mike Snyder
Project:
Genetic regulation of chromatin (with Judith Zaugg)
Oliver Stegle
Projects:
Integrative machine learning to decipher genome function (with Anshul Kundaje)
Mapping the effects of genetic variants from genes to cells to disease (with Stephen Montgomery)
Lars Steinmetz
Projects:
Personalizing dilated cardiomyopathy (with Ron Davis & Utkan Demirci)
Dissecting NGLY1 deficiency (with Carolyn Bertozzi)
Aaron Straight
Research Interests:
Understanding the mechanisms that ensure high fidelity genome maintenance and segregation in eukaryotes including: chromosome biology, cell division and chromatin structure.
Katrin Svensson
Project:
Physiological regulation of metabolism in single cells (with Theo Alexandrov)
Kevin Wang
Research Interests:
Gene expression and epigenetics: how DNA methylation, chromatin modifications, and RNA influence chromatin dynamics to affect gene regulation.
Peter Yang
Research interests:
Developing bio-inspired biomaterials and platform technologies to engineer tissues and organs
Judith Zaugg
Projects:
Using scMulti-omics to probe clinical outcome of child leukemia treatment (with Maya Kasowski)
Multiomics for pulmonary hypertension (with Marlene Rabinovitch)
Genetic regulation of chromatin (with Mike Snyder)