Members of the Life Science Alliance

At the core of the Alliance are our Members - faculty from EMBL and the Stanford University School of Medicine. Their combined expertise spans a broad spectrum of life science research from structural biology and bioinformatics, to chemistry, imaging and genomics. They are committed to the exchange of information to solve complex biomedical challenges together

View their research interests and collaborations below, or click here to view our network and possible areas of overlap.

Join us!

We are always open to accepting new members from EMBL and Stanford University. If our projects or interests match yours, contact us - we would love to hear from you.

Monther Abu-Remaileh

Projects:

Networks of subcellular compartments in health and disease (with Sinem Saka)

Theodore Alexandrov

Projects:

Physiological regulation of metabolism in single cells (with Katrin Svensson)

Alex Bateman

Projects:

ncRNA annotation (with Mike Cherry)

Carolyn Bertozzi

Projects:

Dissecting NGLY1 deficiency (with Lars Steinmetz)

Maria Bernabeu

Project:

Genetic determinants of malarial pathogenetis (with Elizabeth Egan)

Ami Bhatt

Project:

Developing global interaction networks of microbiome-encoded genes (with Peer Bork)

Vivek Bhalla

Research Interests:

Using and developing innovative methodologies to discover novel molecular mechanisms and therapies for kidney health.

Matthieu Boulard

Research Interests:

Molecular basis of chromatin-based silencing and cellular readout of cytosine methylation.

Peer Bork

Project:

Developing global interaction networks of microbiome-encoded genes (with Ami Bhatt)

Howard Chang

Projects:

Dissecting molecular mechanisms of epigenetic silencing (with Edith Heard)

Mike Cherry

Projects:

ncRNA annotation (with Alex Bateman)

Wah Chiu

Research Interests:

The development of cryo-EM methodology to determine 3D cellular structures. We also work on the EMDataResource which is an open access database for 3D EM for developing software, data standards and validation methods.

Isidro Cortes Ciriano

Project:

Quantifying tumour evolution and fitness landscapes with Christina Curtis

Markus Covert

Project:

Integrative model of human cell signalling (with Evangelia Petsalaki)

Christina Curtis

Project:

Quantifying tumour evolution and fitness landscapes with Isidro Cortés-Ciriano

Ron Davis

Projects:

Personalizing dilated cardiomyopathy (with Lars Steinmetz & Utkan Demirci)

Utkan Demirci

Projects:

Personalizing dilated cardiomyopathy (with Lars Steinmetz & Ron Davis)

Claire Deo

Research Interests:

Developing novel molecular tools for advanced biological imaging by combining synthetic chemistry and protein engineering

Gautam Dey

Project:

Cell cycle adaptation to aneuploidy: How do cells adapt to carrying an extra chromosome? (with Gavin Sherlock)

José Dinneny

Research Interests:

Understanding the response of roots to water-limiting conditions and across different organizational scales from the individual cell type to the whole plant.

Ian Dunham

Project:

Machine learning approaches to decipher cell context-specific effects of human disease variation with Anshul Kundaje.

Elizabeth Egan

Project:

Genetic determinants of malarial pathogenetis (with Maria Bernabeu)

Jan Ellenberg

Projects:

Advancing imaging technology (with Tobias Meyer)

Dean Felsher

Research Interests:

How oncogenes initiate and sustain tumorigenesis including: how oncogene activation causes tumor regression, and how tumors escape dependence on oncogenes.

Judith Frydman

Research Interests:

Understanding protein folding including: function and mechanism of chaperones, chaperone networks, ribosome biogenesis, co-translational folding, protein folding homeostasis, misfolding and aggregation disease.

Margaret Fuller

Research Interests:

Regulation of self-renewal, proliferation and differentiation in adult stem cell lineages: including regulation of cell type specific transcription programs, cell-cell communication, and the role of differential mRNA processing and translational control in progression from one cell state to the next.

Eileen Furlong

Research Interests:

Genome regulation and topology during embryonic development including: chromatin topology, chromatin remodelling during cell fate decisions, variation and plasticity in regulatory networks, developmental enhancers, and single cell genomics.

Andrew Gentles

Research Interests:

Computational approaches to understand biological systems using genomic and proteomic data across populations. Most of our work is in cancer and neurodegenerative disease, but we love to hear about any interesting questions!

Miriam Goodman

Research Interests:

Deciphering the molecular events responsible for touch, pain, and position sensation in C. elegans.

Jamie Hackett

Research Interests:

Understanding the mechanistic interplay between genome regulation, chromatin and environmental cues (microbiome), with emphasis on intergenerational effects

Matthias Hentze

Research Interests:

Using biochemical and systems-level approaches to investigate the connections between gene expression and cell metabolism, and their roles in human disease.

Edith Heard

Projects:

Dissecting molecular mechanisms of epigenetic silencing (with Howard Chang)

Keith Hodgson

Projects:

Integrated structural biology (with Matthias Wilmanns)

Susan Holmes

Projects:

Modern statistics for modern biology (with Wolfgang Huber)

KC Huang

Projects:

Predicting drug actions and interactions using big data (with Nassos Typas)

Wolfgang Huber

Projects:

Modern statistics for modern biology (with Susan Holmes)

Maya Kasowski

Project:

Using scMulti-omics to probe clinical outcome of child leukemia treatment (with Judith Zaugg)

Teri Klein

Project:

Pharmacogenomic network analyses in diverse population datasets (with Ellie McDonagh)

Arnaud Krebs

Project:

Transcription Factor cooperativity atlas (with Anshul Kundaje)

Jan Korbel

Project:

Somatic mosaicisms with Alex Urban

Brian Kobilka

Research Interests:

Characterizing the structure and mechanism of G-Protein Coupled Receptors (GPCRs).

Anshul Kundaje

Projects:

Integrative machine learning to decipher genome function (with Oliver Stegle)

Machine learning approaches to decipher cell context-specific effects of human disease variation (with Ian Dunham)

Transcription Factor cooperativity atlas (with Arnaud Krebs)

Jin Billy Li

Research Interests:

RNA editing. We are interested in ADAR-mediated RNA editing, for both its biological function in dsRNA-mediated innate immunity and its utility as a tool for transcriptome engineering.

Julia Mahamid

Research Interests:

We employ state-of-the-art cellular cryo-electron tomography to study phase-separated assemblies in cell biology and to advance our understanding of the molecular organization of the cytoplasm.

José Márquez

Research Interests:

We develop methods and software for high-throughput, automated crystallography and use them to study the structure of sensing and signalling molecules.

Ellie McDonagh

Project:

Pharmacogenomic network analyses in diverse population datasets (with Teri Klein)

Tobias Meyer

Projects:

Advancing imaging technology (with Jan Ellenberg)

Stephen Montgomery

Projects:

Population-scale human iPSC genomics (with Oliver Stegle)

Evangelia Petsalaki

Project:

Integrative model of human cell signalling (with Markus Covert)

Robert Prevedel

Research Interests:

Advanced optical techniques for deep tissue microscopy. In particular, we work in the fields of multi-photon microscopy, active wave-front shaping, photo-acoustics as well as computational imaging. Looking for collaboration in cell & developmental biology and neuroscience, where our novel imaging approaches can give new insights.

Marlene Rabinovitch

Projects:

Multiomics for pulmonary hypertension (with Judith Zaugg)

Georgia Rapti

Research Interests:

Dissecting the cellular and molecular mechanisms of nervous system assembly and the underlying glia–neuron crosstalk, using advanced genetics, genomics and live imaging approaches.

Santiago Rompani

Research Interests:

Studying the function of visual circuits using functional imaging, genetics, virology and behavioural assays.

Sinem Saka

Project:

Networks of subcellular compartments in health and disease (with Monther Abu-Remaileh)

Research Interests:

Spatial and molecular organisation of cells and organelles, morphological profiling, RNA-protein interactions, new labelling approaches, multiplexed fluorescence and super-resolution microscopy techniques, DNA nanotechnology and DNA barcoding method development

Gavin Sherlock

Project:

Cell cycle adaptation to aneuploidy: How do cells adapt to carrying an extra chromosome? (with Gautam Dey)

Yiorgo Skiniotis

Projects:

Structural isoforms in Down syndrome

Mike Snyder

Projects:

Genetic regulation of chromatin (with Judith Zaugg)

Oliver Stegle

Projects:

Integrative machine learning to decipher genome function (with Anshul Kundaje)

Population-scale human iPSC genomics (with Stephen Montgomery)

Tim Stearns

Research Interests:

How the centrosome and primary cilium control cell function and influence signalling and development.

Lars Steinmetz

Projects:

Personalizing dilated cardiomyopathy (with Ron Davis & Utkan Demirci)

Dissecting NGLY1 deficiency (with Carolyn Bertozzi)

Aaron Straight

Research Interests:

Understanding the mechanisms that ensure high fidelity genome maintenance and segregation in eukaryotes including: chromosome biology, cell division and chromatin structure.