Research Pillars
Pillar 1
Human Evidence & Population Context
Integrating epidemiology and clinical data to understand how plastic-associated exposures relate to cardiovascular outcomes across populations and environments.
Pillar 2
Measurement Integrity & Standardization
Developing harmonized protocols, quality controls, and cross-site alignment to improve reliability and reproducibility of exposure and tissue analyses.
Pillar 3
Molecular and Tissue-Level Insights
Linking exposure signals to vascular and plaque biology using advanced molecular and spatial approaches.
Pillar 4
Cellular Pathways & Biological Response
Identifying cellular programs and pathways that shape vascular responses to plastic-associated exposures.
Pillar 5
Translational Models & Prevention-Relevant Insights
Using integrated model systems to assess biological relevance and inform future intervention strategies.