Research Pillars

Pillar 1

Human Evidence & Population Context

Integrating epidemiology and clinical data to understand how plastic-associated exposures relate to cardiovascular outcomes across populations and environments.

Pillar 2

Measurement Integrity & Standardization

Developing harmonized protocols, quality controls, and cross-site alignment to improve reliability and reproducibility of exposure and tissue analyses.

Pillar 3

Molecular and Tissue-Level Insights

Linking exposure signals to vascular and plaque biology using advanced molecular and spatial approaches.

Pillar 4

Cellular Pathways & Biological Response

Identifying cellular programs and pathways that shape vascular responses to plastic-associated exposures.

Pillar 5

Translational Models & Prevention-Relevant Insights

Using integrated model systems to assess biological relevance and inform future intervention strategies.