The Kapiloff Laboratory is recruiting new post-doctoral fellows and students on an ongoing basis. Highly motivated, enthusiastic cellular or molecular biologists and physiologists with an interest in either neuronal or cardiac signal transduction are encouraged to apply by contacting Dr. Kapiloff directly. Current research in the Kapiloff lab addresses how the formation of multimolecular protein complexes confers specificity in intracellular signaling and how these complexes are important for the function of cardiac myocytes in pathological remodeling and for the function of central nervous system neurons in stroke. A major focus of the lab has been the mAKAP scaffold protein that coordinates crosstalk between cAMP, calcium and MAP-kinase signaling pathways and that is important for the induction of pathological myocyte hypertrophy in the heart and for neurite extension and neuroprotection in the eye. Other projects include the study of novel scaffold proteins for the phosphatase calcineurin and for small GTPases. Research in the Kapiloff laboratory spans the breadth of signal transduction research from biochemistry to cell biology, including live cell imaging with FRET biosensors, to in vivo animal physiology using genetically modified mouse models. Dr. Kapiloff is a member of the Biophysics PhD Program at Stanford.