Welcome to the Soltesz Lab website! Our lab is part of the Stanford School of Medicine, Department of Neurosurgery, and is led by Dr. Ivan Soltesz.
We are interested in how brain cells communicate with each other in the normal brain, and how the communication changes in epilepsy.
Postdoctoral fellows and graduate students in the lab employ closely integrated, cutting-edge experimental and computational modeling techniques to understand normal and epilepsy-related plasticity in neuronal networks. The techniques include simultaneous patch clamp recordings from rigorously identified interneurons and principal cells, in vivo recordings and functional imaging, closed-loop optogenetics, behavioral methods, and biologically highly realistic large-scale supercomputational modeling approaches.
One Scientist's Quest To Vanquish Epileptic Seizures
Ivan Soltesz studies epilepsy in mice, but says children with chronic seizures are his inspiration. He's closing in on a way to quell the seizures with light — and without drugs' side effects.
12/23/2016 Paper published: Interneuronal mechanisms of hippocampal theta oscillation in a full-scale model of the rodent CA1 circuit
04/04/2016 Ivan Soltesz has been awarded computing time allocation on Blue Waters, the NSF-funded petascale computing system, for constructing full-scale computational models of the hippocampus.
02/18/2016 Paper published: Cannabinoid Control of Learning and Memory through HCN Channels Congratulations, Mattia!
11/09/2015 Review paper published: Microcircuits in Epilepsy: Heterogeneity and Hub Cells in Network Synchronization
10/30/2015 Our optogenetic epilepsy work has been written up in the NIH News In Health newsletter for November 2015.
10/22/2015 Good news: Five past members of the Soltesz lab received faculty jobs just within the last two years! Congratulations, we are proud of you all!
If you are interested in joining the lab, please contact Ivan Soltesz.
05/19/2016 Soltesz Lab research mentioned in Nature News article, Light-controlled genes and neurons poised for clinical trials
05/12/2016 Ivan Soltesz has been elected to the Hungarian Academy of Sciences! http://mta.hu/english/introducing-the-newly-elected-members-of-the-hungarian-academy-of-sciences-106486