About HIMC

The HIMC was developed in 2007 by the Institute for Immunity, Transplantation, and Infection (Mark Davis, Ph.D., director) in conjunction with the Center for Clinical Immunology (C. Garrison Fathman, founder).

In accordance with Stanford policy:

If work done with the HIMC produces data in a publication, you must acknowledge us ("Stanford Human Immune Monitoring Center") in the publication. Further, if HIMC staff provide significant experimental design, data interpretation, or other intellectual contribution (as evaluated by the PI), then it is expected that these individuals will be coauthors on the publication.

Goals of the HIMC

  1. To provide standardized, state-of-the art immune monitoring assays at the RNA, protein, and cellular level.  These are assays that have already been validated in the HIMC.  Additional information and protocols are available in the links above.
  2. To test and develop new technologies for immune monitoring.  We are always developing new assays in the above areas, as well as testing new potential immune monitoring platforms.  Please let us know if you would like to explore a new assay or technology with us.
  3. To efficiently archive, report, and mine data from immune monitoring studies, so as to increase the value of the data and to assist in biomarker discovery.  The HIMC uses Stanford Data Miner for integration of data from the standard HIMC assays, along with de-identified clinical and demographic data.  One year after release of results to an investigator, data will be released for all users of the HIMC to access, unless appealed by the investigator for reasons of still-pending publication.

Assay results are available through two systems:

  • Basecamp, our project management system, allows for easy downloading of individual experiment reports and ancillary data.  It also facilitates discussion between investigators and HIMC, and allows investigators to post files such as sample lists and clinical metadata, for incorporation into our database (see below).
  • Stanford Data Miner, our online database, integrates the results of all standard assays, with clinical and demographic metadata, across projects.  Each investigator can access his/her own projects as well as HIMC shared data.

Please contact yaelhr@stanford.edu if you have HIMC data and need help accessing either of these systems.

Contact

For general questions, contact Holden Maecker , HIMC director
at maecker@stanford.edu.

Support for the HIMC

The Institute of Immunity, Transplantation and Infection (ITI) proudly acknowledges the support of: The HEDCO Foundation, The Russell Foundation, The Sidney E. Frank Foundation, Ronald Sand Foundation, Bob and Patty Moore, John Brennan, Becton, Dickinson and Co, the NIH Clinical and Translational Science Award, Stanford Cancer Center Support Grant from NCI, and  the Office of the Dean. The creation and growth of the HIMC was made possible by their generous contributions.

To help further support this bold endeavor, please contact Anne Marie Krogh , Director of Major Gifts, Stanford Medical Center Development, or tel: (650) 721-6929.