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Immunology Highlights

2022

  • – NPR

    A substance found in young spinal fluid helps old mice remember

    A team at Stanford University has reversed memory loss in old mice by flooding their brains with spinal fluid taken from young animals. The finding may hold promise for Alzheimer's research. A growth factor found in the fluid also improved memory, though to a lesser degree, says Tony Wyss-Coray, a neuroscientist and senior author of the study.

  • – Scope

    A new approach to vaccinations: 3D printed patches

    As the COVID-19 pandemic hit and vaccine development went into hyperdrive, Joseph DeSimone, an expert in precision drug delivery and 3D printing technology, had an idea for a new research project: a 3D-printed vaccine patch. In partnership with Peter Kim, PhD, professor of biochemistry at Stanford, we've recently tested a SARS-CoV-2 protein-based vaccine patch in mice, and we're also starting to test mRNA vaccines via patch. By the end of this year, I hope we'll finalize the SARS-CoV-2 vaccine formulation.

  • – KCBS Radio

    New research out of Stanford links marijuana use with heart disease

    New research out of Stanford University links marijuana use with heart disease but a molecule found in soymilk may be the key to combating that. The research showed that THC causes inflammation. Dr. Joseph Wu, Director of the Stanford Cardiovascular Institute and Professor of Medicine and Radiology told KCBS Radio that if someone smokes or takes edibles it causes the same amount of inflammation.

  • – SciTechDaily

    Not All Dietary Fibers Are Equal – Health Benefits of Dietary Fiber Vary

    Researchers revealed in the journal Cell Host & Microbe on April 28th, 2022, that the health benefits of dietary fiber vary between individuals and may depend on the precise kind of fiber and the dose taken. “Our results demonstrate that the physiological, microbial, and molecular effects of individual fibers differ substantially,” says senior study author Michael Snyder, a geneticist at Stanford School of Medicine. “Further, our results demonstrate the tantalizing prospect of using targeted fibers, mediated by the microbiome, to drive health and systems biology in a predictable, personalized direction.”

  • – New Atlas

    Stanford study links marijuana use to increased heart attack risk

    A robust new study led by researchers from Stanford University has found a strong association between increased risk of heart attack and regular marijuana use. Joesph Wu, senior author on the new study, said it is important medical and recreational marijuana users are aware of the potential adverse cardiovascular effects of the drug. And moving forward it will be crucial to develop ways to mitigate these adverse effects.


2021

  • – Scope

    Who's on first? Duking out scientific paper authorship order

    Determining the order of authors on a scientific paper can be tricky. Unless you're a pair of video gaming graduate students. Recently Stanford researcher Garry Nolan, PhD, tweeted about an unconventional way two researchers in his laboratory who had each contributed equally to a study decided who should be listed first on the print version of the paper.

  • – BBC

    BBC Radio 5 live - 5 Live Science Podcast, Life in plastic, is it fantastic?

    As the government moves to Plan B - what actually happens when you catch the new variant?

  • – Stanford Professor Garry Nolan Is Analyzing Anomalous Materials From UFO Crashes

    Stanford Professor Garry Nolan Is Analyzing Anomalous Materials From UFO Crashes

    A Q&A with one of the foremost scientists studying UAPs, and what he hopes to learn by systematically studying bizarre and difficult-to-explain incidents. Dr. Garry Nolan is a Professor of Pathology at Stanford University. His research ranges from cancer to systems immunology. Dr. Garry Nolan has also spent the last ten years working with a number of individual analyzing materials from alleged Unidentified Aerial Phenomenon.

  • – Gizmodo

    The Coronavirus Can Infect and Possibly Hide in Fat Cells, Study Finds

    The preliminary findings could partially explain why people living with obesity are at higher risk of severe covid-19. “This could well be contributing to severe disease,” senior author, Catherine Blish, an immunologist at the Stanford University School of Medicine, told the New York Times. “We’re seeing the same inflammatory cytokines that I see in the blood of the really sick patients being produced in response to infection of those tissues.”

  • – Mail Online

    Blood from ultra-fit mice 'could hold the key to staving off dementia'

    Injections of blood from young adult mice that are getting lots of exercise benefited the brains of sedentary mice the same age, according to a study by the Stanford School of Medicine in California. 'The discovery could open the door to treatments that, by taming brain inflammation in people who don't get much exercise, lower their risk of neurodegenerative disease or slow its progression,' said Professor Tony Wyss-Coray, of the Stanford School of Medicine in California, which carried out the research.


October 7, 2021 - The Edge
How can technology help you track real time data about your health and wellbeing? And why should you track anyway? In this episode, Michael Snyder, professor of genetics, talks about how tracking can help you gain deeper understanding of what is going on in your body at a physiological level. Often, illnesses begin developing in our bodies quietly, before any symptoms begin to show up. Snyder’s research shows that by tracking on a regular basis, we can pre-empt diseases. Health data collection using wearable tech can help us take a proactive approach toward prevention of disease. And like they say, prevention is better than cure.

  • – News Center

    Study predicts who may benefit from CAR-T cell therapy for blood cancers

    CAR-T cell therapy works for many types of blood cancers, but more than half of patients relapse. A Stanford study provides a clue as to why. The researchers showed a correlation between the density of the target molecules on the cell surface and the likelihood that a patient will respond well to CAR-T cell therapy. They also devised a way to assess the function of engineered CAR-T cells before they are used in patients. Crystal Mackall, MD, the Ernest and Amelia Gallo Family Professor and a professor of pediatrics and of medicine and David Miklos, MD, PhD, professor of medicine and chief of bone marrow transplantation and cellular therapy are co-senior authors of the study, which was published online July 26 in Nature Medicine.

  • – The Stanford Daily

    Vaccine supplement can expand immune system’s virus protection, Stanford research finds

    Certain additives can strengthen vaccines to protect the body from a broad range of viruses, researchers at the Stanford School of Medicine found in a study published in late June in Cell. Lead author Florian Wimmers found that a chemical can boost immune defenses to various viruses when added to vaccines.

  • – The Scientist Magazine

    How the Second mRNA Vaccine Bolsters Immunity

    A study looks beyond T and B cell responses to show how the Pfizer COVID-19 vaccine elicits a strong innate immune response. The Scientist spoke with lead author Bali Pulendran, an immunologist at Stanford University, about what he and his colleagues found regarding the Pfizer vaccine’s effects on the immune system.

  • – Scope

    A better COVID-19 vaccine?

    A new way to deliver mRNA as a COVID-19 vaccine may avoid side effects and increase customization to prevent infection. Now immunologist and oncologist Ronald Levy, MD, and chemists Paul Wender, PhD, and Robert Waymouth, PhD, are exploring another way to get viral mRNA into cells using a novel technique I wrote about in 2018. They published their results recently in ACS Central Science.

  • – News Center

    Stanford study ties milder COVID-19 symptoms to prior run-ins with other coronaviruses

    In COVID-19 patients whose symptoms were mild, Stanford researchers found that they were more likely than sicker patients to have signs of prior infection by similar, less virulent coronaviruses. Senior author, Mark Davis, PhD, a professor of microbiology and immunology; director of Stanford’s Institute for Immunity, Transplantation and Infection; and a Howard Hughes Medical Institute investigator and first author, postdoctoral fellow Vamsee Mallajosyula, PhD, first confirmed that some portions of SARS-CoV-2’s sequence are effectively identical to analogous portions of one or more of the four widespread common-cold-causing coronavirus strains.


June 23, 2021 – NBC Bay Area

NBC Bay Area: COVID-19 and brain inflammation

Stanford researchers have found signs of inflammation, genetic changes and impaired circuitry in the brains of people killed by COVID-19, important clues to the mysterious “brain fog” and mental struggles reported by many patients. Tony Wyss-Coray, professor of neurology and neurological sciences at Stanford Medicine provides comments.

  • – MarketWatch

    How COVID vaccine's mRNA technology could help cure other diseases

    Scientists and companies are trying to harness the mRNA technology to develop vaccines against cancer and other diseases. Bali Pulendran, Violetta L. Horton Professor And Professor Of Microbiology And Immunology and of Pathology, comments on the future on vaccines.

  • – News Center

    Stanford researchers find signs of inflammation in brains of people who died of COVID-19

    A detailed molecular analysis of tissue from the brains of individuals who died of COVID-19 reveals extensive signs of inflammation and neurodegeneration, but no sign of the virus that causes the disease. Tony Wyss-Coray, PhD, professor of neurology and neurological sciences at Stanford, shares senior authorship with Andreas Keller, PhD, chair of clinical bioinformatics at Saarland University.

  • – News Center

    Climate change linked to longer allergy season in Bay Area, Stanford study finds

    Air levels of pollen and mold spores in the San Francisco Bay Area are elevated for about two more months per year than in past decades, and higher temperatures are to blame, a Stanford Medicine study has found, led by senior author, Kari Nadeau, MD, PhD, professor of medicine and of pediatrics at Stanford School of Medicine.

  • – Stanford Today

    Faculty Women’s Forum announces 2021 award winners

    The 2021 Faculty Women’s Forum Awards honor individuals for their outstanding work supporting women at Stanford through role modeling, allyship, leadership and sponsorship. Stanford Immunology faculty Dr. Joy Wu, an associate professor of medicine (endocrinology, gerontology and metabolism) in the School of Medicine is honored in the Allyship Award category.

  • – News Center

    Smartwatch data can predict blood test results, study reports

    Stanford researchers found that data from smartwatches can flag early signs of some health conditions and predict the results of simple blood tests. Scientists from the lab of Michael Snyder, PhD, professor and chair of genetics, tracked data from smartwatches, blood tests and other tests conducted in a doctor’s office in a small group of study participants.


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