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Immunology Highlights


  • – SciTechDaily

    Cracking the Code of Autoimmune Diseases: New Approach Identifies Key Protein Fragments

    Study opens pathway to better diagnosis and treatment of autoimmune diseases. Researchers from Washington University, Stanford University, and Oxford University have developed a method to identify protein fragments and immune cells that cause autoimmune reactions. Co-corresponding author K. Christopher Garcia, PhD, and co-first author Xinbo Yang, PhD, of Stanford Medicine.

  • – Washington Post

    Gene-edited cells move science closer to repairing damaged hearts

    New research offers a path toward transplants that can fix damage from a heart attack without causing life-threatening arrhythmias. “The arrhythmias are one of the key roadblocks. The investigators conducted an important study but will need to test more animals to show these genetically modified cells do not cause irregular rhythms and can improve heart function,” said Joseph Wu, director of the Stanford Cardiovascular Institute.

  • – Scope

    Unconventional Paths: Merging computation and biology

    Purvesh Khatri has followed a winding path to medicine -- one that started with a hate for biology and a career in engineering.

  • – Becker's Healthcare

    Stanford Medicine performs first beating-heart transplant

    Stanford (Calif.) Medicine surgeons are the first to transplant a beating heart into a patient. The first surgery, performed by Joseph Woo, MD, chair of cardiothoracic surgery, and his team, lasted only four hours. Surgeons received the heart from a cardiac-death donor via "Heart-in-a-Box" technology. The device keeps the heart pumping with oxygenated blood. The team sewed the beating heart into the patient.

  • – Stanford News Center

    Durable, low-cost COVID-19 vaccine could help fill in gaps around the world

    In a study led by Stanford Medicine researchers, a low-cost COVID-19 vaccine that does not require refrigeration provided immunity in rhesus monkeys for one year. “Our motivation was to come up with a vaccine that would provide worldwide access to vaccination,” said Peter Kim, PhD, the Virginia and D.K. Ludwig Professor in Biochemistry. “In the case of the mRNA vaccines, for example, they are expensive, difficult to make and require storage in freezers. So, we wanted to solve those problems with this vaccine.”


  • – News Center

    New blood test to identify infections could reduce global antibiotic overuse

    A diagnostic test developed by Stanford Medicine scientists can separate bacterial and viral infections with 90% accuracy, the first to meet standards set by the World Health Organization. The new test is described in a paper published Dec. 20 in Cell Reports Medicine. “Antimicrobial resistance is continuously rising, so there has been a lot of effort to reduce inappropriate antibiotic usage,” said Purvesh Khatri, PhD, associate professor of medicine and biomedical data science, and the senior author of the paper. “Accurately diagnosing whether a patient has a bacterial or viral infection is one of the biggest global health challenges.”

  • – News Center

    Researchers may have found a new path for halting cancer cell production

    After finding long, repetitive sequences in the genomes of seven kinds of cancer, researchers at Stanford Medicine and their colleagues developed a molecule that curbed their production. Although the scientists aren’t sure what role the repetitive sequences play in cancer, they were encouraged that they appeared to have found a way to inhibit the creation of more cancer cells. “The most dramatic result was that you could actually target them and stop cell proliferation,” said Michael Snyder, PhD, professor and chair of the department of genetics.

  • – Human Performance Alliance

    Speeding up bone healing in menopausal females

    lder women heal bone fractures slower than men. Now a team has found that a single, localized delivery of estrogen to a fracture can speed up healing in postmenopausal mice. The findings could have implications for the way fractures in women are treated in the future. “The majority of stem cell research is done on male animals. There’s very little research that has actually been done on females,” said Wu Tsai Alliance member Charles Chan, PhD, an assistant professor of surgery at Stanford University and co-senior author of the paper published Oct. 30 in Nature Communications. “The research is long overdue, especially the question of why women heal differently from men.”

  • – Pharmacy Times

    Expert: Immune Reconstitution With Orca-T Reveals ‘New Realm of Engineered Donor Grafts’ for Patients With Hematologic Malignancies

    Pharmacy Times interviewed Everett Meyer, MD, PhD, medical and scientific director of the Cellular Therapy Facility, Stanford Health Care and Assistant Professor of Medicine, Blood and Marrow Transplantation, Stanford University, on the poster presentation titled “Rapid Immune Reconstitution and Elevated Regulatory T Cell Frequencies in Patients Treated with Orca-T” at the 64th American Society of Hematology (ASH) Annual Meeting and Exhibition in New Orleans, Louisiana.

  • – Helio

    Stanford researcher receives award for lifetime achievement in hematology

    Irving Weissman, MD, will receive the Wallace H. Coulter Award for Lifetime Achievement in Hematology at this year’s ASH Annual Meeting & Exposition. Weissman, director of Stanford Medicine’s Institute for Stem Cell Biology and Regenerative Medicine, has made several important contributions to hematology over the past 5 decades.


  • – Scope

    Who's on first? Duking out scientific paper authorship order

    Determining the order of authors on a scientific paper can be tricky. Unless you're a pair of video gaming graduate students. Recently Stanford researcher Garry Nolan, PhD, tweeted about an unconventional way two researchers in his laboratory who had each contributed equally to a study decided who should be listed first on the print version of the paper.

  • – BBC

    BBC Radio 5 live - 5 Live Science Podcast, Life in plastic, is it fantastic?

    As the government moves to Plan B - what actually happens when you catch the new variant?

  • – Stanford Professor Garry Nolan Is Analyzing Anomalous Materials From UFO Crashes

    Stanford Professor Garry Nolan Is Analyzing Anomalous Materials From UFO Crashes

    A Q&A with one of the foremost scientists studying UAPs, and what he hopes to learn by systematically studying bizarre and difficult-to-explain incidents. Dr. Garry Nolan is a Professor of Pathology at Stanford University. His research ranges from cancer to systems immunology. Dr. Garry Nolan has also spent the last ten years working with a number of individual analyzing materials from alleged Unidentified Aerial Phenomenon.

  • – Gizmodo

    The Coronavirus Can Infect and Possibly Hide in Fat Cells, Study Finds

    The preliminary findings could partially explain why people living with obesity are at higher risk of severe covid-19. “This could well be contributing to severe disease,” senior author, Catherine Blish, an immunologist at the Stanford University School of Medicine, told the New York Times. “We’re seeing the same inflammatory cytokines that I see in the blood of the really sick patients being produced in response to infection of those tissues.”

  • – Mail Online

    Blood from ultra-fit mice 'could hold the key to staving off dementia'

    Injections of blood from young adult mice that are getting lots of exercise benefited the brains of sedentary mice the same age, according to a study by the Stanford School of Medicine in California. 'The discovery could open the door to treatments that, by taming brain inflammation in people who don't get much exercise, lower their risk of neurodegenerative disease or slow its progression,' said Professor Tony Wyss-Coray, of the Stanford School of Medicine in California, which carried out the research.

October 7, 2021 - The Edge
How can technology help you track real time data about your health and wellbeing? And why should you track anyway? In this episode, Michael Snyder, professor of genetics, talks about how tracking can help you gain deeper understanding of what is going on in your body at a physiological level. Often, illnesses begin developing in our bodies quietly, before any symptoms begin to show up. Snyder’s research shows that by tracking on a regular basis, we can pre-empt diseases. Health data collection using wearable tech can help us take a proactive approach toward prevention of disease. And like they say, prevention is better than cure.

  • – Scope

    What to do (and not do) when you win the Nobel Prize

    Three of Stanford Medicine's Nobel laureates, including Andrew Fire, George D. Smith Professor of Molecular and Genetic Medicine and Professor of Pathology and of Genetics, offer advice to future winners about hearing the news and what to expect next in their careers.

  • – The Scientist Magazine

    When the Immune Response Makes COVID-19 Worse

    If the immune system makes mistake--reacting late or getting the target wrong--it can amplify the damage wrought by SARS-CoV-2.

  • – News Center

    Statins may be effective treatment for patients with ulcerative colitis

    People with ulcerative colitis who are also taking statins have about a 50% decreased risk of colectomies and hospitalization, according to a Stanford Medicine study. Purvesh Khatri, PhD, associate professor of medicine and of biomedical data science, and his team tracked down a connection between a handful of drugs and decreased symptoms of ulcerative colitis.

  • – Business Insider

    Why Stanford is spending millions to incorporate Apple Watches and Fitbits into medical care

    Stanford is exploring consumer wearable devices, including Apple Watches and Fitbits, to monitor heart rates and predict COVID-19 symptoms. Michael Snyder, professor of genetics, leads many of the health systems' wearable projects and says it's up to health systems to quickly figure out whether the data's useful to doctors and how to efficiently extract it from the devices.

  • – Scope

    Blood test predicts chances of lymphoma relapse after therapy

    Stanford Medicine Scientists have devised a blood test to predict some cancer relapses after patients have already been treated.To understand whether ctDNA tracking might hint at relapse, Miklos, who heads Stanford Medicine's Blood and Marrow Transplantation and Cellular Therapy division, Matthew Frank MD, PhD assistant professor of medicine, and their labs enrolled 72 patients with large B-cell lymphoma, who had received CAR-T cell therapy, which involves genetically engineering certain immune cells to find and eliminate specific cancer cells.

June 23, 2021 – NBC Bay Area

NBC Bay Area: COVID-19 and brain inflammation

Stanford researchers have found signs of inflammation, genetic changes and impaired circuitry in the brains of people killed by COVID-19, important clues to the mysterious “brain fog” and mental struggles reported by many patients. Tony Wyss-Coray, professor of neurology and neurological sciences at Stanford Medicine provides comments.

  • – FierceBiotech

    A cancer vaccine built from stem cells? Stanford candidate shows promise in pancreatic tumors

    A team at Stanford University showed that a cancer vaccine made from induced pluripotent stem cells, together with an immune adjuvant, could protect against pancreatic cancer in mouse models. It induced strong T-cell and antibody responses while dialing down immune suppressor cells. Stanford Immunology researchers include Edgar G. Engleman, professor of pathology and of immunology and rheumatology and Joseph C. Wu, director of the Stanford Cardiovascular Institute and the Simon H. Stertzer, MD, professor of medicine and radiology.

  • – Scope

    Evading exhaustion to improve CAR-T cell therapy

    'Resting' exhausted cancer-fighting immune cells enhances their tumor-killing activity, which may help people with blood and solid cancers. Crystal Mackall, the Ernest and Amelia Gallo Family professor and professor of pediatrics and of medicine, and instructor Evan Weber are featured in this post.

  • – Scope

    Stanford postdoc enters her youngsters in vaccine COVID trial

    Anxious to protect her children, Stanford immunology researcher Zina Good has enrolled her two young children Pfizer’s COVID-19 vaccine clinical trial for kids. Yvonne Maldonado is also quoted in this post.

  • – News Center

    Team science award recognizes 8 pediatric cancer researchers at Stanford

    The team, composed of researchers at nine academic institutions, has published more than 100 papers and treated nearly 1,000 children with cancer in early-phase clinical trials. Eight Stanford Medicine scientists are among a group of pediatric cancer researchers being honored with the 2021 Team Science Award from the American Association for Cancer Research. Stanford Immunology recipients of this year’s award are Crystal Mackall, MD and Jennifer Cochran, PhD.

  • – Scope

    Milestone stem cell transplant helps child beat rare disease

    A revolutionary technique helps cure a 9-year-old girl who was Stanford Children's Health's 1,000th stem cell transplant patient. Alice Bertaina, associate professor of pediatrics in stem cell research, is mentioned in this post.