Instrumentation available at the HTS @ The Nucleus (ChEM-H W008 & CCSR 0133)

The HTS @ The Nucleus has instrumentation for high-throughput (96 and 384 well microplate) liquid handling, high-throughput detection,  and high-content screening. Our small molecule HTS liquid handling system includes an integrated robotic arm for fully automated enzyme/protein and cell-based screening, while our siRNA liquid handling system allows for fully automated siRNA transfections, cell fixing and staining, and high content imaging.

For more information select one of the tabs on the left.

The Caliper LS Staccato small molecule liquid handling system and the Analyst GT were purchased with NCRR NIH Instrumentation grant number S10RR019513. The upgraded Agilent (formerly Velocity11) siRNA Screening system and advanced automated options for the ImageXpress Micro were purchased with NCRR NIH Instrumentation grant number S10RR026338, and the ImageXpress Micro Confocal and Precise Automation robot were purchased with NIH Shared Instrumentation grant number S10OD026899.

MicroPlate Readers

Tecan Infinite M1000 and M1000 PRO schedule (multimode plate reader). (View only)

BMG ClariostarPlus CCSR-0133 and ChEM-H W008 schedule (multimode plate reader). (View only)

Flexstation II 384 schedule (fluorescent intensity and kinetic experiments). (View only) 

Liquid Handling Robots

• Multidrop schedule. (View only) 
  Wellmate schedule. (View only) 
  PlateWasher schedule. (View only) -please contact us first to use platewashers
  Velocity11 VPrep schedule. (View only) 
  Agilent Bravo System and/or Plate Sealer schedule. (View only) 
  

High Content Imager

ImageXpress Micro Confocal check schedule HERE. (View only)

Analysis Computer1, Analysis Computer2

The funding for the purchase of most of our instrumentation was provided by the NIH Shared Instrumentation Grant numbers S10RR019513, S10RR026338, S10OD026899 and by an anonymous donation.