Publications

Alan Cheng, MD

Edward C. and Amy H. Sewall Professor of Otolaryngology — Head & Neck Surgery and, by courtesy, Pediatrics

Hair Cell Development

Ward, Kristina M, Alanna Coughran, Monterosa Lee, Matthew B Fitzgerald, Alan G Cheng, Kay W Chang, and Iram Ahmad. “Prevalence of Cochlear Nerve Deficiency and Hearing Device Use in Children with Single‐Sided Deafness.” Otolaryngology-Head and Neck Surgery 169, no. 2 (August 2023): 390–96. https://doi.org/10.1002/ohn.255.

Moatti, Adele, Dylan Silkstone, Taylor Martin, Keith Abbey, Kendall A Hutson, Doug Fitzpatrick, Carlton J Zdanski, Alan G Cheng, Frances S Ligler, and Alon Greenbaum. “Assessment of Drug Permeability through an Ex Vivo Porcine Round Window Membrane Model.” IScience 26, no. 6 (June 16, 2023): 106789–89. https://doi.org/10.1016/j.isci.2023.106789.

Takashi Udagawa, Erisa Takahashi, Norifumi Tatsumi, Hideki Mutai, Yukari Kondo, Patrick Atkinson, Tatsuo Matsunaga, et al. “Pax3 Deficiency Diminishes Melanocytes in the Developing Mouse Cochlea.” Research Square, (June 9, 2023). https://doi.org/10.21203/rs.3.rs-2990436/v1.

Wei, Eric X, Kara D Meister, Karthik Balakrishnan, Alan G Cheng, and Z Jason Qian. “Ankyloglossia: Clinical and Sociodemographic Predictors of Diagnosis and Management in the United States, 2004 to 2019.” Otolaryngology-Head and Neck Surgery, (March 30, 2023). https://doi.org/10.1002/ohn.332.

Xia, Anping, Takashi Udagawa, Patricia Martinez Quinones, Patrick Atkinson, Brian E Applegate, Alan G Cheng, and John S Oghalai. “The Impact of Targeted Ablation of One Row of Outer Hair Cells and Deiters’ Cells on Cochlear Amplification.” Journal of Neurophysiology 128, no. 5 (November 14, 2022): 1365–73. https://doi.org/10.1152/jn.00501.2021.

Moon, Peter K, Z Jason Qian, Iram Ahmad, Konstantina M Stankovic, Kay W Chang, and Alan G Cheng. “Infectious Complications Following Cochlear Implant: Risk Factors, Natural History, and Management Patterns.” Otolaryngology-Head and Neck Surgery 167, no. 4 (October 2022): 745–52. https://doi.org/10.1177/01945998221082530.

Moatti, Adele, Chen Li, Sasank Sivadanam, Yuheng Cai, James Ranta, Jorge A. Piedrahita, Alan G. Cheng, Frances S. Ligler, and Alon Greenbaum. “Ontogeny of Cellular Organization and LGR5 Expression in Porcine Cochlea Revealed Using Tissue Clearing and 3D Imaging.” iScience 25, no.8 (June 30, 2022). https://doi.org/10.1016/j.isci.2022.104695.

Kim, Jinkyung, Sriram Hemachandran, Alan G. Cheng, and Anthony J. Ricci. “Identifying Targets to Prevent Aminoglycoside Ototoxicity.” Molecular and Cellular Neuroscience 120 (May 2022): 103722. https://doi.org/10.1016/j.mcn.2022.103722.

Moon, Peter K, Johanna Theruvath, J.C.S Chang, Yohan Song, Katie Shpanskaya, Maryam Maleki, Alan G Cheng, Iram Ahmad, and Kristen W Yeom. “MRI Correlates of Ototoxicity in the Auditory Pathway in Children Treated for Medulloblastoma.” Otology & Neurotology 43, no. 1 (January 2022): e97–104. https://doi.org/10.1097/mao.0000000000003336.

Jan, Taha A., Yasmin Eltawil, Angela H. Ling, Leon Chen, Daniel C. Ellwanger, Stefan Heller, and Alan G. Cheng. “Spatiotemporal Dynamics of Inner Ear Sensory and Non-Sensory Cells Revealed by Single-Cell Transcriptomics.” Cell Reports 36, no. 2 (July 13, 2021): 109358. https://doi.org/10.1016/j.celrep.2021.109358.

Jansson, Lina, Michael Ebeid, Jessica W. Shen, Tara E. Mokhtari, Lee A. Quiruz, David M. Ornitz, Sung-Ho Huh, and Alan G. Cheng. “β-Catenin Is Required for Radial Cell Patterning and Identity in the Developing Mouse Cochlea.” Proceedings of the National Academy of Sciences of the United States of America 116, no. 42 (October 15, 2019): 21054–60. https://doi.org/10.1073/pnas.1910223116.

Najarro, Elvis Huarcaya, Jennifer Huang, Adrian Jacobo, Lee A. Quiruz, Nicolas Grillet, and Alan G. Cheng. “Dual Regulation of Planar Polarization by Secreted Wnts and Vangl2 in the Developing Mouse Cochlea.” Development (Cambridge, England) 147, no. 19 (October 5, 2020): dev191981. https://doi.org/10.1242/dev.191981.

Sun, Haiying, Tian Wang, Patrick J. Atkinson, Sara E. Billings, Wuxing Dong, and Alan G. Cheng. “Gpr125 Marks Distinct Cochlear Cell Types and Is Dispensable for Cochlear Development and Hearing.” Frontiers in Cell and Developmental Biology 9 (2021): 690955. https://doi.org/10.3389/fcell.2021.690955.

Human Hair Cell Biology

Aaron, Ksenia A., Davood K. Hosseini, Yona Vaisbuch, Mirko Scheibinger, Nicolas Grillet, Stefan Heller, Tian Wang, and Alan G. Cheng. “Selection Criteria Optimal for Recovery of Inner Ear Tissues from Deceased Organ Donors.” Otology & Neurotology: Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, February 3, 2022. https://doi.org/10.1097/MAO.0000000000003496.

Hair Cell Degeneration & Regeneration

Kim, Grace S., Tian Wang, Zahra N. Sayyid, Jessica Fuhriman, Sherri M. Jones, and Alan G. Cheng. “Repair of Surviving Hair Cells in the Damaged Mouse Utricle.” Proceedings of the National Academy of Sciences 119, no. 15 (April 5, 2022). https://doi.org/10.1073/pnas.2116973119.

Yona Vaisbuch, Davood K Hosseini, Andreas Wagner, Bernhard Hirt, Marcus Mueller, Ravikumar Ponnusamy, Stefan Heller, Alan G Cheng, Hubert Löwenheim, and Ksenia A Aaron. “Surgical Approach for Rapid and Minimally Traumatic Recovery of Human Inner Ear Tissues from Deceased Organ Donors.” Otoloty & Neutorology 43, no. 4 (April 2022): e519–25. https://doi.org/10.1097/mao.0000000000003500.

Aaron, Ksenia A., Davood K. Hosseini, Yona Vaisbuch, Mirko Scheibinger, Nicolas Grillet, Stefan Heller, Tian Wang, and Alan G. Cheng. “Selection Criteria Optimal for Recovery of Inner Ear Tissues from Deceased Organ Donors.” Otology & Neurotology 43, no. 4 (April 2022): e507–14. https://doi.org/10.1097/mao.0000000000003496.

Galjaard, H., R. Willemsen, A. T. Hoogeveen, G. M. Mancini, S. Palmeri, F. W. Verheijen, and A. D’Azzo. “Molecular Heterogeneity in Human Beta-Galactosidase and Neuraminidase Deficiency.” Enzyme 38, no. 1–4 (1987): 132–43. https://doi.org/10.1159/000469199.

Jan, Taha A., Yasmin Eltawil, Angela H. Ling, Leon Chen, Daniel C. Ellwanger, Stefan Heller, and Alan G. Cheng. “Spatiotemporal Dynamics of Inner Ear Sensory and Non-Sensory Cells Revealed by Single-Cell Transcriptomics.” Cell Reports 36, no. 2 (July 13, 2021): 109358. https://doi.org/10.1016/j.celrep.2021.109358.