Datasets

Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression

Original publication: Mattis, Katia K., Nicole AJ Krentz, Christoph Metzendorf, Fernando Abaitua, Aliya F. Spigelman, Han Sun, Jennifer M. Ikle et al. "Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression." Diabetologia 66, no. 4 (2023): 674-694.

Data is available through the EGA https://ega-archive.org to request the data please read the data access agreement below and complete the application form. Your application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study: EGAS00001006314

Dataset: EGAD00001009740

Data Access Committee: EGAC00001002712

Application to access the Data

Data access agreement

PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development.

Original publication: Lau, Hwee Hui, Nicole AJ Krentz, Fernando Abaitua, Marta Perez-Alcantara, Jun-Wei Chan, Jila Ajeian, Soumita Ghosh et al. "PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development." Nature Communications 14, no. 1 (2023): 6119.

Data is available through the EGA https://ega-archive.org to request the data please read the data access agreement below and complete the application form. Your application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study: EGAS00001006036

Dataset: EGAD00001008582

Data Access Committee: EGAC00001002542

Application to access the Data

Data access agreement

Analysis of Differentiation Protocols Defines a Common Pancreatic Progenitor Molecular Signature and Guides Refinement of Endocrine Differentiation" published at Stem Cell Reports in 2020

Original publication: Wesolowska-Andersen et al., Stem Cell Reports. 2020 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962645/

Data is available through the EGA - https://ega-archive.org to request the data please read the data access agreement below and complete the application form. Your application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study: EGAS00001003513

Dataset: EGAD00001004823 (RNA-seq)

Dataset: EGAD00001004824 (ATAC-seq)

Data Access Committee: EGAC00001000335

Data access agreement for ATAC-seq

Data access agreement for RNA-seq

Application to access the ATAC-seq data

Application to access the RNA-seq data

INSPIRE consortium

Original publication: Vinuela et al Nature Communications

2020-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528108/

Data is available through the EGA https://ega-archive.org to request the data please read the data access agreement below and complete the application form. You application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study: EGAS00001003997

Dataset: EGAD00001006149

Data Access Committee: EGAC000010001390

Application to access the Data

Data access agreement

Cis-eQTL mapping of human pancreatic islets

Original publication: van de Bunt et al., PLoS Genetics, 2015 – https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005694

Data is available through the EGA https://ega-archive.org to request the data please read the data access agreement below and complete the application form. You application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study: EGAS00001001265

Dataset: EGAD00001001601

Data Access Committee: EGAC00001000335

Application to access the Data

Data access agreement

Characterization of a human iPSC-derived endocrine pancreas model

Original publication: van de Bunt et al., Islets, 2016 – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987020/

Data is available through the EGA https://ega-archive.org to request the data please read the data access agreement below and complete the application form. You application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study: EGAD00001002148

Dataset: EGAD00001001601

Data Access Committee: EGAC00001000335

Application to access the Data

Data access agreement

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci - WGBS dataset

Original publication: Thurner et al Elife 2018 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828664/

Data is available through the EGA https://ega-archive.org to request the data please read the data access agreement below and complete the application form. You application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study:EGAS00001002592

Dataset: EGAD00001003946

Data Access Committee: EGAC00001000335

Application to access the Data

Data access agreement

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci – ATAC-seq dataset

Original publication: Thurner et al Elife 2018 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828664/

Data is available through the EGA https://ega-archive.org to request the data please read the data access agreement below and complete the application form. You application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study:EGAS00001002592

Dataset: EGAD00001003947

Data Access Committee: EGAC00001000335

Application to access the Data

Data access agreement

Genes associated with pancreas development and function maintain open chromatin in iPSCs generated from human pancreatic beta cells - RNA dataset

Original publication: Thurner et al Stem Cell Reports 2017 - https://www-cell-com.stanford.idm.oclc.org/stem-cell-reports/pdf/S2213-6711(17)30427-7.pdf

Data is available through the EGA (link here please - https://ega-archive.org to request the data please read the data access agreement below and complete the application form. You application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study:EGAS00001002591

Dataset: EGAD00001003780

Data Access Committee: EGAC00001000335

Application to access the Data

Data access agreement

Genes associated with pancreas development and function maintain open chromatin in iPSCs generated from human pancreatic beta cells – ATAC-Seq dataset

Original publication: Thurner et al Stem Cell Reports 2017 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831005/

Data is available through the EGA https://ega-archive.org to request the data please read the data access agreement below and complete the application form. You application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study: EGAS00001002591

Dataset: EGAD00001003759

Data Access Committee: EGAC00001000335

Application to access the Data

Data access agreement

Understanding human fetal pancreas development using subpopulation sorting and RNA sequencing

Original publication: Ramond et al., Development, 2018 https://dev-biologists-org.stanford.idm.oclc.org/content/145/16/dev165480

Data is available through the EGA https://ega-archive.org to request the data please read the data access agreement below and complete the application form. You application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study: EGAS00001003127

Dataset: EGAD00001004210

Data Access Committee: EGAC00001001039

Application to access the Data

Data access agreement

Characterization of a human iPSC-derived islet differentiation model.

Data is available through the EGA https://ega-archive.org to request the data please read the data access agreement below and complete the application form. You application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study: EGAS00001002721

Dataset: EGAD00001003807

Data Access Committee: EGAC00001000335

Application to access the Data

Data access agreement

RNA-seq profiling of NKX6.1 reporter iPSC lines for isolation and analysis of functionally relevant neuronal and pancreas populations

Original publication: Gupta et al., Stem Cell Res. 2018 https://www.sciencedirect.com/science/article/pii/S1873506118301119?via%3Dihub

Data is available through the EGA - https://ega-archive.org to request the data please read the data access agreement below and complete the application form. You application will be considered by the Data Access Committee and when approved EGA will release the data.

Forms should be returned to agloyn@stanford.edu

Study: EGAS00001002802

Dataset: EGAD00001003911

Data Access Committee: EGAC00001000335

Application to access the Data

Data access agreement

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