Frontiers in Biology

Frontiers in Biology: 2023

DATE SPEAKER TITLE
Jan 11  Kelly Monk  Vollum Inst, OHSU  Genetic and molecular mechanisms of neuron-glial interactions 
Jan 18  Michael Laub
 MIT
 New players in the molecular arms race between bacteria and phages 
Jan 25  Dennis Slamon  UCLA Title pending
Feb 1  Antonio Giraldez  Yale University Understanding the mechanisms of genome activation using genomics and expansion microscopy 
Feb 8  TBA    
Feb 15  Arun Radhakrishnan  UT Southwestern  How cells control cholesterol 
Feb 22  Katherine Pollard  Gladstone Inst, UCSF  Deep learning discovery of variants that alter 3D genome folding 
March 1 Tracy Johnson UCLA Title pending 
March 8 Sun Hur  Harvard  Title pending 
March 15  Maya Inaba  U of Connecticut  Asymmetric stem cell division and gene regulation 
March 22  TBA    
March 29  Christopher Westlake  NIH  Title pending 
April 5 Aaron Zorn  Cincinnati Children’s Hospital  Genomic specificity of Wnt- responsive transcription 
April 12 Matthew Spitzer
 UCSF
 Decoding decision making in the immune system through multicellular interactions 
April 19 James Hurley
 UC Berkeley
 Switches that turn autophagy and lysosome biogenesis on and off 
April 26  Marc Freeman  Vollum Institute, OHSU  Neuronal remodeling in complex metazoans 
May 3  Li Lan  Harvard University  Understanding and targeting RNA- dependent DNA repair in cancer 
May 10  TBA    
May 17 Binyam Mogessie  Yale University  Emerging mechanisms of chromosome segregation in mammalian eggs 
May 24 Samantha Lewis  UC Berkeley  Mitochondrial heterogeneity across biological scales 
May 31

TBA

    
June 7 Steve Henikoff  Fred Hutchinson Cancer Center

Genome-wide mapping of protein- DNA interaction dynamics 

Frontiers in Biology: 2022

DATE SPEAKER TITLE
Jan 19 Heinrich Jasper Genentech  Reprogramming and regeneration: interventions to target age-related diseases
Jan 26 Polly Fordyce Stanfrod Leveraging microfluidics for high- throughput biophysics, biochemistry and single-cell biology
Feb 2 Sara Walker Arizona State University Life is what?
Feb 9 Kristy Red-Horse Stanford  Development, regeneration, and repair of blood vessels in the heart
Feb 23 Kelly Nguyen MRC UK Replenishing the ends: Structural mechanism of human telomerase holoenzyme
March 2  Astrid Gillich Calico Dissecting alveolar patterning, maintenance, and aging at single-cell resolution
March 9 Myriam Heiman MIT Understanding connections between cellular heterogeneity and Huntington’s Disease pathogenic mechanisms: insights from unbiased molecular profiling and genetic screening in the CNS
March 23 Cigall Kadoch Dana-Farber Cancer Institute  Structure and function of ATP- dependent chromatin remodeling complexes in human disease
March 30

Malene Hanseb

 The Buck Institute  Cellular recycling in aging and disease: The importance of taking out the trash
April 6 Bart De Strooper UK Dementia Research Ins 

The neuron and glia cell alterations in Alzheimer’s Disease
May 18 Emily Balskus Harvard Deciphering the human microbiome with chemistry
May 25

Hongkui Zeng

 

Allen Institute for Brain Science

 Understanding brain cell type diversity
Sep 28

Rushika Perer

 UCSF Identifying new features and functions of ysosomes in cancer
Oct 5 Vanessa Ruta Rockefeller U  Mechanisms of adaptive behavior, from receptors to circuits
Oct 12 Jimmie Ye UCSF Exponentiating single cell genomics
Oct 19 David Pincus U of Chicago The heat shock response as a condensate cascade
Oct 26 Thomas Graf Centre for Genomic Regulation, Barcelona, Spain From cell reprogramming to early embryo development
Nov 2 Schraga Schwartz Weizmann Institute, Rehovot, Israel Deciphering the m6a code
Nov 9 Julia Salzman Stanford Genomic discovery across disparate subfields with a highly efficient, reference free statistical algorithm
Nov 16 Ian Maze Mt. Sinai Icahn School of Medicine  Protein monoaminylation: novel mechanisms of neural development,  plasticity and disease
Dec 7

Carrie Partch

 UC Santa Cruz

Morning larks and night owls shed light on human circadian timekeeping
DATE SPEAKER TITLE
2021
Jan 13 James Nunez  UCSF Programmable transcriptional memory by CRISPR-based epigenome editing

Jan 27

 Eric Haag  U of Maryland Using Caenorhabditis nematodes to reveal the impacts of sexual mode on cells, genomes and species
Feb 3 Ralph DeBerardinis  UTSW  Metabolic perturbations and their role in human diseases
Feb 10 Luciano Marraffini  Rockefeller CRISPR-Cas13 immunity: sacrificing the host for the population
Feb 17 Long Cai Caltech Spatial genomics: in situ profiling in single cells
March 3 Maria Elena Torres-Padilla Helmholtz Zentrum, Germany Epigenetic mechanisms of cellular plasticity and reprogramming to totipotency
March 10 Irene Miguel-Aliaga  MRC Imperial College  Sex and reproductive differences in intestinal plasticity
March 17  Cliff Tabin  Harvard

Vignettes from a dev bio/evo devo lab: What makes a limb cell a limb cell? And how did birds evolve the capacity to vocalize?
March 31 Derk ten Berge Erasmus Medical Center  Slicing up the pluripotency spectrum – how pluripotent state transitions drive embryo morphogenesis
April 14 Gustavo Silva Duke University K63 ubiquitin and the regulation of translation during oxidative stress
April 21 Maria Elena Torres-Padilla Helmholtz Zentrum, Germany Epigenetic mechanisms of cellular plasticity and reprogramming to totipotency
May 5 Levi Garraway Genentech  Frontiers in therapeutic development
May 12 Karine Gibbs UC Berkeley Micro-crowdsourcing: How a swarming bacterial pathogen use a local sense of identity to assemble and move as a community
May 26 Huda Zoghbi Baylor College of Medicine  Epigenetics and Brain Plasticity: Lessons from Rett Syndrome and other MECP2 disorders
Jun 2 Georgia Panagiotakos UCSF O Ca(2+)ptain! My Ca(2+)ptain! Dynamic regulation of intracellular signaling during cortical development
Sep 22 Dominique Bergmann Stanford Constantly on edge: recruiting cell polarity for developmental flexibility
Oct 13 Andrea Pauli IMP Vienna  Fundamental principles during the egg-to-embryo transition – from fertilization to translational regulation
Oct 27 Martin Kampmann UCSF How do neurons and glia deal with stress and disease? New insights from CRISPR-based functional genomics
Nov 3 Celina Juliano UC Davis Mechanisms of development and regeneration in hydra
Winter  -  2019
16-Jan Alejandro Sanchez Alvarado Stowers "Understanding the source of regenerative ability in animals" DB and BC switched Jan 16 with Jan 23
30-Jan Maria Barna Stanford  
6-Feb Tom Kornberg UCSF  
13-Feb Ibrahim Cisse MIT "Super-resolution imaging of transcription in live mammalian cells"
20-Feb Tania Baker MIT  
27-Feb Andreas Matouschek UT Austin "Deciphering the proteasomal degradation code"
6-Mar Yoseph Barash U Penn "Big data, small data: Getting from genotype to phenotype through transcriptome variations identification and prediction"
13-Mar Sergio Grinstein U of Toronto "Ion channels and the cytoskeleton in phagocytosis and micropinocytosis"
20-Mar Katie Peichel U of Bern "Genetics of adaptation and speciation in sticklebacks"
27-Mar Lulu Qian Caltech "Algorithmic and architectural foundations for programmable molecular machines: DNA robots, information-processing circuits, and reconfigurable nanostructures"
Spring  -  2019
3-Apr David Segal UCD "Changing Your Mind: Targeted Epigenetic Editing in the Brain"
10-Apr Samara Reck-Peterson UCSD "The cellular interstate system: deciphering the mechanisms of microtubule-based transport"
17-Apr Frank Chan Max Planck "The long-legged mouse and the impossible hybrid - the genetics of genome evolution in the mouse"
24-Apr Jennifer Lippincott-Schwartz Janelia "Membrane dynamics and organelle biogenesis - lipid pipelines and vesicular carriers"
1-May Sabine Cordes U Toronto "Post-transcriptional and post-translational mechanisms shaping vertebrate social behavior"
8-May Piali Sengupta Brandeis Food mind control: Regulation of sensory  behaviors by internal feeding state in C. elegans
15-May Kim Orth U of Texas Southwestern "BLACK SPOT, BLACK DEATH, BLACK PEARL: THE TALES OF BACTERIAL EFFECTORS"
10/22 - asked Billy Li and Mike Bassik if BC can take for Cliff Tabin
22-May Matt Waldor Harvard  
29-May Swathi Arur MD Anderson "Of worms, mice and women:  ERK signaling sculpts small RNA pathway in development and disease"
5-Jun Andy Minn U Penn  

Frontiers in Biology: 2018-2019

DATE SPEAKER TITLE
Fall  -  2018
26-Sep Ulrich Hartl Max Planck "Molecular chaperones in protein folding and quality control" - Genetics (J Frydman booked Clark separately)
3-Oct Dan Jarosz Stanford "Mapping biochemical drivers of phenotypic change" (Oct 1-3 Biochem Retreat)
10-Oct Jim Ferrell Stanford "Trigger waves in cell signaling"
17-Oct Kryn Stankunas U Oregon "How the zebrafish got its fin back: signaling niches, and cell transitions of regeneration"
24-Oct Alan Lambowitz UT Austin "Thermostable Group II Intron Reverse Transcriptases (TGIRTs): Evolutionary signficance, structure, and RNA-seq applications"
31-Oct Prashant Mali UCSD  
7-Nov James Chen (Zhijian) UTSW "Enemy within - how DNA triggers immune defense and autoimmune disease through the cGAS-STING pathway"
14-Nov Kristin Baldwin Scripps "Through the looking glass: Exploring neuron diversity and human genetics using reprogramming"
28-Nov Wendell Lim UCSF "Hacking cells: Learning by building" - switched w/ Genetics 8/7/18 -Genetics will take March 27 or May 22
5-Dec Gisou van der Goot U Lausanne "Protein palmitoylation in health and disease: from Wnt signaling to anthrax"
12-Dec Rosie Alegado U of Hawaii "Influence of bacterial compounds on multicellular development of choanoflagellates"
Winter  -  2019
16-Jan Alejandro Sanchez Alvarado Stowers "Understanding the source of regenerative ability in animals" DB and BC switched Jan 16 with Jan 23
30-Jan Maria Barna Stanford  
6-Feb Tom Kornberg UCSF  
13-Feb Ibrahim Cisse MIT "Super-resolution imaging of transcription in live mammalian cells"
20-Feb Tania Baker MIT  
27-Feb Andreas Matouschek UT Austin "Deciphering the proteasomal degradation code"
6-Mar Yoseph Barash U Penn "Big data, small data: Getting from genotype to phenotype through transcriptome variations identification and prediction"
13-Mar Sergio Grinstein U of Toronto "Ion channels and the cytoskeleton in phagocytosis and micropinocytosis"
20-Mar Katie Peichel U of Bern "Genetics of adaptation and speciation in sticklebacks"
27-Mar Lulu Qian Caltech "Algorithmic and architectural foundations for programmable molecular machines: DNA robots, information-processing circuits, and reconfigurable nanostructures"
Spring  -  2019
3-Apr David Segal UCD "Changing Your Mind: Targeted Epigenetic Editing in the Brain"
10-Apr Samara Reck-Peterson UCSD "The cellular interstate system: deciphering the mechanisms of microtubule-based transport"
17-Apr Frank Chan Max Planck "The long-legged mouse and the impossible hybrid - the genetics of genome evolution in the mouse"
24-Apr Jennifer Lippincott-Schwartz Janelia "Membrane dynamics and organelle biogenesis - lipid pipelines and vesicular carriers"
1-May Sabine Cordes U Toronto "Post-transcriptional and post-translational mechanisms shaping vertebrate social behavior"
8-May Piali Sengupta Brandeis Food mind control: Regulation of sensory  behaviors by internal feeding state in C. elegans
15-May Kim Orth U of Texas Southwestern "BLACK SPOT, BLACK DEATH, BLACK PEARL: THE TALES OF BACTERIAL EFFECTORS"
10/22 - asked Billy Li and Mike Bassik if BC can take for Cliff Tabin
22-May Matt Waldor Harvard  
29-May Swathi Arur MD Anderson "Of worms, mice and women:  ERK signaling sculpts small RNA pathway in development and disease"
5-Jun Andy Minn U Penn  

Frontiers in Biology: 2017-2018

DATE SPEAKER   TITLE
Fall  -  2017
27-Sep Xiaowei Zhuang  Harvard Illuminating biology at the nanoscale and systems scale by imaging 
4-Oct Francesca Cole MDAnderson CC Meiosis and chromosome segregation in mammals: why younger isn’t always better”
11-Oct Beatrice Hahn Upenn Out of Africa: Ape origins of Human AIDS and Malaria
18-Oct Monte Winslow Stanford Molecular Determinants of Cancer Growth and Metastasis 
25-Oct Nadav Ahutiv UCSF Functional characterization and therapeutic targeting of gene regulatory elements
31-Oct Jim Rothman  Yale Rothman couldn't make Nov 1, we couldn't another speaker  for Nov 1 - Title: "Transiting the Golgi Stack: New Insights into an Old Problem"
8-Nov Steve McKnight UTSW (BC Journal Club)
15-Nov Mark Krasnow Stanford  
29-Nov Michael Marletta UCB Nitric Oxide Signaling: From Prokaryotes to Humans
6-Dec Kim Cooper UCSD What big feet you have!” Identification of Genes Associated with Skeletal Proportion
13-Dec Christine or Johnathan Seidman Harvard (BC Journal Club)
Winter  -  2018
10-Jan Tom Cech U Colorado LncRNAs, PRC2 recruitment, and epigenetic silencing
17-Jan Diana Laird UCSF Heterogeneity and selection in developing germ cells
24-Jan Emma Lundberg SciLifeLab Spatial proteomics and the single cell 
31-Jan Sekar Kathiresan Mass Gen Hearth attack: from gene discovery to risk prediction, biology and therapeutics
7-Feb Kevan Shokat UCSF Chemical tricks for drugging the undruggable
14-Feb Hugo Bellen Baylor  Drosophila to unravel pathogenic mechanisms of neurological diseases: a Zika target and ApoE4 in Alzheimer’s Disease (BC taking since G took Feb 21)
21-Feb Genetics: Sex Chromosome Symposium   Genetics (Marcia) took Feb 21 from Biochem for Genetics-Sex Chromosome Symposium
28-Feb Wallace Marshall UCSF Pattern formation and regeneration in a single cell  (MUNZER)
7-Mar Jay Shendure U Washington Global views of development
14-Mar Bruno Reversade EMBO, Singapore A master switch for limb numbers
21-Mar Elizabeth Chen UTSW To invade or to resist:  That is the question - Mechanisms of cell-cell fusion   (BC Journal Club)
28-Mar Gloria Brar  UCB  
Spring  -  2018
4-Apr Daniel Kahne Harvard Molecular machiens that make membranes
11-Apr Kees (Cornelis) Murre UCSD Non-coding transcription instructs chromatin folding and compartmentalization to dictate enhancer-promoter communication
25-Apr David Bartel MIT MicroRNAs and other regulatory RNAs
2-May Oskar Hallatschek UCB Microbes under pressure (BC Journal Club)
9-May Stirling Churchman Harvard MS Probing gene regulation from the nucleus to mitochondria
16-May Cecilia Moens Fred Hutchison/ U Wash What Happens in Vagus: topographic mapping by the Vagus nerve.  [James (Zhijian) Chen cannot because he's receiving an award.  Instead he'll speak on Nov 7, 2018]
23-May Sun Hur Harvard Antiviral innate immunity: duplex RNA-mediated protein aggregation
30-May Amita Sehgal U Penn Biology of bedtime: understanding circadian rhythms and sleep
6-Jun Alanna Schepartz Yale  
13-Jun Jennifer Garrison Buck Institute Cellular and circuit mechanisms of neuropeptide signaling