Current Issues in Genetics (CIG)

Current Issues In Genetics: 2018 - 2022

Date Presenter Talk  
11/4/22 Kelsey Fryer Investigating the role of chromatin associated RNAs in centromere maintenance  
11/4/22 Julien Sage Abscopal responses against metastatic cancer  
10/28/22 Connor Duffy Systematic interrogation of Alzheimer's disease risk signaling  
10/28/22 Margaret Fuller Alternative mRNA processing and changes in cell state  
10/21/22 Theo Susanto Investigating translation heterogeneity across cell types, development, and disease  
10/21/22 Jennifer Doherty Leveraging genetic interactions for Antiviral Drug Development in Enteroviruses
10/14/22 Ching Pin Cheng RiboCannon: A novel genetic approach to study ribosomal proteins  
10/14/22 Casey Gifford Building it up to break it down; using hiPSCs to model heart development and disease  
10/7/22 Rebecca Culver Longitudinal intestinal microbiome cultivation reveals factors governing site-specific colonization  
10/7/22 Anne Brunet Mechanisms of brain aging and rejuvenation  
6/24/22 Connor Duffy Systematic interrogation of Alzheimer's disease risk genetics  
6/24/22 Angela Zhang Developing a deep learning model to predict induced pluripotent stem-cardiomyocyte outcomes  
6/3/22 Rosa Ma Interpreting the genetic basis of heart structure and function  
6/3/22 Helen Kang Systematic Perturb-seq to connect heart disease GWAS loci to causal genes and pathways  
5/27/22 Nick Kalogriopoulos A synthetic GPCR platform for cell-based cancer therapy  
5/27/22 Dylan Maghini The gut microbiome and non-communicable disease in African women: improving representation in genomics research  
5/20/22 Alyssa (Benjamin) Yoxsimer What causes stickleback pebble disease?  
5/20/22 Cheryl Hayashi Caught in the Web: My Journey to Unravel the Complexity of Spider Silk  
5/13/22 Rachel Ungar & Page Goddard Breaking down builds – how genome construction impacts RNA-seq and rare disease diagnostics  
5/6/22 Sai Zhang Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis  
4/29/22 Akshay Sanghi Dissecting mechanisms of metastatic thyroid cancer evolution  
4/29/22 Stephanie Malia Fullerton Clinical Translational Genomics and the Challenge of Diversifying Precision Medicine  
4/22/22 Danny Cotter The impact of consanguinity on X-chromosomal genomic sharing  
4/22/22 Roshni Patel Genetic interactions drive heterogeneity in causal variant effect sizes  
4/15/22 Johannes Linder Interpreting the impact of genetic variation on human Polyadenylation  
4/15/22 Matthew Ravalin Building a single-component biosensor for detecting SARS-CoV-2  
4/8/22 Jacob Schreiber Navigating the Pitfalls of Applying Machine Learning in Genomics  
4/8/22 Hakhamanesh Mostafavi Why most GWAS hits have not yet been detected as eQTLs”  
4/1/22 Emily Greenwald Aberrant RNA synthesis by transcription polymerases  
4/1/22 Jarod Rutledge Organ-specific aging signatures in the plasma proteome predict disease status and progression  
3/11/22 Adam Reeves Evolution of diapause in the African turquoise killifish by remodeling ancient gene regulatory landscape  
2/25/33 Nicholas Hughes Evolvable barcoding of single cells using Cas12a  
2/25/33 Kyomi Igarashi Investigation of Species-Specific Molecular Characteristics of Implantation  
2/11/22 Katelyn McKown Divergent roles of stomatal identity gene FAMA in Arabidopsis and Brachypodium stomatal development  
2/11/22 Wei Qin Time-resolved tandem proximity labeling for protein translocation profiling  
2/4/22 Abby Bergman & Sedona Murphy Return of results and discussion: How can the recent survey be used to improve the department”  
1/28/22 Rebecca Culver Profiling of the human intestinal microbiome and bile acids under physiologic conditions”  
1/28/22 Nicole Gay Molecular transducers of endurance exercise training in rats  
1/21/22 Shibin Hu ADAR1 utilizes independent mechanisms to suppress MDA5 and PKR activation by cellular double-stranded RNA  
1/21/22 Sedona Murphy Polycomb-mediated genome organization provides a scaffold for epigenetic memory without liquid-liquid phase separation  
1/14/22 Alex Kern Determining the Environment-Specific Effects of Natural Variants on Ergosterol Pathway Function  
1/14/22 Casey Gifford Getting to the heart of the matter: complex genetics and congenital heart disease  
1/7/22 Kelsey Fryer Investigating the role of chromatin associated RNAs in centromere maintenance  
1/7/22 Jennifer Doherty Leveraging Genetic Interactions for Antiviral Drug Development  
12/10/22 Gavin Sherlock Cornering Darwin’s Daemons: Pareto Fronts Constrain Adaptation in Yeast  
11/19/21 Le Cong CRISPR screen identifies neuronal channel as possible entry factor and druggable target for SARS-CoV-2  
11/19/21 Briana Mittleman DNA and NDAs: A geneticist path to law school  
10/12/21 Anne Villeneuve The Genetics and Evolution of Genetics  
10/12/21 Laksshman Sundaram Heart-ATAC: Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and noncoding mutations in congenital heart disease”  
10/12/21 Amy Fan Chen NEAT-seq: Simultaneous profiling of intra-nuclear proteins, chromatin accessibility, and gene expression in single cells  
11/5/21 Adele Xu ALIBi: a tool for investigating subcellular populations of ribosomes.  
11/5/21 Laura Attardi p53 repurposes a lung regeneration program in tumor suppression  
10/29/22 Serena Sanulli Chromatin dynamics across scales  
10/29/22 Ami Bhatt The art of (microbial) conversation  
10/22/21 Anna Gloyn Precision Medicine in Monogenic Diabetes: Diagnosing: Diabetes now we have the whole genome in our hands”  
10/22/21 Livnat Jerby Redirecting multicellular circuits to unleash targeted immune responses  
10/15/21 Mark Kay Linking a LncRNA to miR122 and their roles as a non-coding tumor suppressor gene(s) in the liver  
10/15/21 Kay Kobak Generating and Harnessing a Robust Placental Epigenom  
10/8/21 Euan Ashley Warp Speed Genomes  
10/8/21 Howard Chang Cancer genes beyond chromosomes  
5/22/20 Binbin Chen Computationally identify potential SARS-CoV-2 epitopes and immune evasion  
5/22/20 Alex Colville High-throughput approaches to dissect cellular senescence  
5/15/20 Ben Ober-Reynolds Untangling alopecia with single-cell transcriptomics and chromatin accessibility”  
5/15/20 Laura Donohue Leveraging genome-wide mapping of regulatory landscapes to identify combinatorial transcription factor modules in health and disease  
5/8/20 Robert Coukos High-throughput investigation of protein proximity and protein-protein interaction with a light-gated transcriptional reporter  
5/8/20 Olivia Mae de Gode Annotating long non-coding RNAs through gene expression pattern  
5/1/20 Alissa Severson Population genetics of the Muwekma Ohlone: comparing ancient and modern sample  
5/1/20 Josh Tycko High-throughput discovery and characterization of human transcriptional effector domains  
4/24/20 Aparna Rajpurkar Leveraging deep learning to connect super-resolution DNA traces to transcription  
4/24/20 John Gorzynski Genetic etiologies of fibrosing cardiomyopathy in great apes  
4/17/20 John Gorzynski Genetic etiologies of fibrosing cardiomyopathy in great apes  
4/17/20 Ragini Phansalkar Vascular development in the fetal human heart  
4/10/20 David Yao  Mapping enhancer-promoter interactions with phenotype-driven CRISPR screens  
4/10/20 Nasa Sinnott-Armstrong GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background  
4/3/20 Albert Hinman VDSB-3 Cooperates with DSB-1 and DSB-2 to Promote Meiotic Double-Strand Break Formation  
4/3/20 Roy Ang Investigating epistasis among genetic polymorphisms with single-nucleotide resolution  
2/28/20 Kristen Wells Combined Transient Ablation and Single Cell RNA Sequencing Resolves Thymic Epithelial Cell Development  
2/28/20 Le Cong Single-Cell Genetic Barcoding and Decoding to Probe Cancer Evolution  
2/21/20 Nathan Abell Functional Consequences of Rare Genetic Variation on Gene Expression and Splicing in the GTEx Consortium  
2/21/20 Monther Abu-Remaileh The emerging Roles of the Lysosome In Metabolic Homeostasis  
1/24/20 Wenyu Zhou Defining Ageotypes for Personal Aging Assessment and Intervention  
1/24/20 Jesse Engreitz Activity-by-Contact Model for Enhance-Promoter Regulation from thousands of CRISPR Perturbation  
1/17/20 Tyler Shimko Building a Computational Toolkit to Expedite Protein Engineering  
1/17/20 Brayon Fremin Studying Translation and Identifying Small Proteins in the Microbiome  
12/13/19 Nikki Teran Making Sense of Nonsense: Interpreting Nonsense Mediated Decay Across Individuals and Tissues  
12/13/19 Mike Bassik Development of new CRISPR/Cas9-based Tools to Identify Cancer Drug Targets and Mechanisms of Phagocytosis  
12/6/19 Siming Zhang Integrated Analysis of Gene Expression, DNA Methylation and Chromatin Accessibility in Human Induced Neurons with the 15q13.3 Microdeletion  
12/6/19 Andrew Fire What thy memory can contain: Adventure in the investigation of cellular memory  
11/8/19 Hannah De Jong Deep mutational scanning to find cardiac disease gene variants  
11/8/19 Ami Bhatt Monitoring Microbial Chatter  
11/1/19 Robin Yeo Chromatin dynamics & cell migration changes during neural stem cell aging  
11/1/19 Mark Kay Capsid engineering for enhanced gene transfer and genome engineering in humans”  
8/10/19 Albert Hinman Genomes are made to be broken  
8/10/19 David Gennart Identifying a Chromatin Signature of CAR T Cell Exhaustion  
8/10/19 Nikki Teran Using Allele Specific Expression for Rare Disease Diagnostics  
6/7/19 Rui Tang G-BaToN: a glowing cell interaction report system  
6/7/19 Qin Lin Genetic Mapping of A-to-I RNA Editing in Human Tissues Links Population Variation and Autoimmune Diseases  
5/31/19 Roy Ang Investigating genome-wide epistasis in single nucleotide variants across differentially adapted S. cerevisiae strains  
5/31/19 Massa Shoura Chasing Genome Dynamics Through Time and Space  
5/24/19 Albert Hinman The Role of DSB-3 in Promoting and Regulating Meiotic Double-Strand Break Formation  
5/24/19 Kyuho Han Genome-wide CRISPR screens in lung cancer spheroids identify 3D growth specific cancer vulnerabilities  
5/17/19 Theo Susanto Rapid enrichment of ribosome-associated proteins across cell types, tissues, and species  
5/17/19 Tao Sun Cytoplasmic RNA editing is required to suppress MDA5-mediated dsRNA innate immunity  
5/10/19 Kristen Lynn Wells Single cell sequencing defines immediate precursor of stable medullary thymic epithelial cell populations  
5/10/19 Nathan Samuel Abell Resolving and Interpreting Highly Linked Non-Coding Genetic Associations in Humans  
5/3/19 Nasa Sinnott-Armstrong The genetic basis of serum and urine laboratory tests  
5/3/19 Kotaro Fujii Decoding the Function of Ribosome Tentacles  
4/26/19 Josh Gruber HAT1 drives a gene-metabolite circuit at the center of chromatin  
4/26/19 Adam Wilkinson Long-Term Ex Vivo Expansion Of Hematopoietic Stem Cells  
4/12/19 Brayon Fremin Validation of structured RNAs in the human gut microbiome  
4/12/19 Tyler Shimko Graph convolutional neural networks: a tool to understand and design molecular interactions  
3/15/19 Hannah De Jong Predicting hypertrophic cardiomyopathy variants by high-throughput mutagenesis  
3/15/19 Siming Zhang Molecular characterization of 15q13.3 microdeletion using an iPSC model  
3/8/19 Robin Yeo The dynamic chromatin landscape of neural stem cell aging  
3/8/19 Jessica Ribado  Illuminating microbial dark matter using long read technologies  
2/22/19 Fiona Tamburini Exploring the gut microbiome and cardiometabolic disease in two South African populations  
2/22/19 Euan Ashley Better diagnosing rare genetic disease  
2/15/19 Evan Boyle Coaxing coessential gene signal from pooled CRISPR knockout screens  
2/15/19 Kelly Ormond RISPR in the news  
2/8/19 Eli Moss Genomes from Metagenomes: New Tools for Complex Microbial Communities  
2/8/19 Michael Cherry Something Old and Something New  
2/1/19 Kimberly Tsui Systematic identification of regulators of antibody-drug conjugate internalization and intracellular trafficking using CRISPR-Cas9 screens  
2/1/19 Jonathan Pritchard Trans eQTLs drive architecture of human complex traits  
1/25/19 Keyla Badillo Current Issues in Preeclampsia and Population Genetics  
1/25/19 Minx Fuller How to rapidly switch cell types:  Developmentally regulated alternative 3’ end processing of nascent transcripts controls the menu of proteins expressed at consecutive steps during differentiation  
1/25/19 Keyla Badillo Current Issues in Preeclampsia and Population Genetics  
1/25/19 Tang Hua Harmonizing genetic ancestry & self-identified race/ethnicity in multi-ethnic biobanks  
1/18/19 Billy Li ADAR RNA editing: innate immune evasion and transcriptome engineering  
1/18/19 Minx Fuller How to rapidly switch cell types by alternative 3’ end processing of nascent transcripts  
1/13/19 Michael Sikora Selecting and sequencing clonally expanded T cells  
1/13/19 Hiro Nakauchi Xenogeneic barrier in interspecies chimera formation  
12/7/18 Han Sun CDK-RAB fusion and activation in cancers  
12/7/18 Anshul Kundaje Interpretable deep learning models of high-resolution transcription factor binding profiles (ChIP-nexus/exo) reveal the diversity of functional combinatorial cis-regulatory sequence grammars  
11/9/18 Matthew J. McCoy The Role of Gene Complexity in the Evolution and Function of Nervous Systems  
11/2/18 Julien Sage Generation and maintenance of intra-tumoral heterogeneity in SCLC  
11/2/18 Alistair Boettiger Visualizing DNA folding and transcription in embryogenesis  
10/5/18 Karla Kirkegaard Dominance, Drugs and Viruses  
9/28/18 Arend Sidow The magic of diploid genome reconstruction for detection of structural variation  
9/28/18 Phillip Cleves Using Transcriptomics and Reverse Genetics to Understand Cnidarian-Dinoflagellate Symbiosis  
8/3/18 Roy Ang From barrel to bedside: Investigating genome-wide epistasis in single nucleotide variants across differentially adapted S. cerevisiae strains   
8/3/18 Nathan Abell Characterizing Regulatory Genetic Variation by Massively Parallel Reporter Assay Across the Allele Frequency Spectrum  
7/20/18 Kristen Wells Single cell sequencing informs stages of thymic cell development  
7/20/18 Cameron Prybol Regulating the Ca-dependent genetic etiology of hypertrophic cardiomyopathy  
7/13/18 Nasa Sinnott-Armstrong USF1 modulates chronotype and consolidates sleep  
7/13/18 Tyler Shimko Biophysical measurements inform structure- function models of Transcription factor binding specificities