Current Issues in Genetics (CIG)

Current Issues In Genetics: 2018 - 2021

Date Presenter Talk  
10/1/21 Polly Fordyce Short tandem repeats recruit transcription factors to tune eukaryotic gene expression  
10/1/21 Abbey Thompson Genetics at The Tech Interactive  
9/24/21 Shanta Rajaram Careers in Health Science Administration at the NIH  
9/24/21 Jesse Engreitz Mapping the regulatory wiring of the genome to connect disease variants to functions  
4/30/21 Alex Kern Characterizing Selection on the Ergosterol Pathway Through Targeted Metabolomics and Precision Genome Editing  
4/30/21 Rebecca Culver Colons or semi-colons? Punctuating the composition of microbial communities throughout the human gastrointestinal tract
4/16/21 Stephen Boeynaems Phase separation as a common killing strategy of bioactive peptides  
4/16/21 Adam Reeves Evolution of diapause in the African killifish by remodeling of ancient gene regulatory landscapes  
4/9/21 Kelsey Fryer Investigating the role of chromatin associated RNAs in centromere maintenance  
4/9/21 Michael Snyder Big Data, Health and COVID-19  
3/26/21 Matthew Buckley Cell type-specific aging clocks quantify rejuvenation of neurogenic niche  
3/19/21 Laura Donohue Leveraging genome-wide mapping of regulatory landscapes to identify combinatorial TF vocabularies in health and disease   
3/19/21 David Gennert The dynamic chromatin landscape of CAR T cell exhaustion  
3/12/21 Robert Coukos High-throughput investigation of protein localization and  protein-protein interaction   
3/12/21 Casey Gifford Getting to the heart of the matter: complex genetics and congenital heart disease  
2/12/21 Olivia de Goede Examining the potential for cis-natural antisense transcripts to trigger endogenous immune responses  
2/12/21 Daphne Martschenko Gatekeeping in Genetics: Shifting the Priorities of the Research Enterprise  
1/22/21 Nasa Sinnott-Armstrong Mechanisms underlying environmental and genetic control of cardiometabolic disease  
1/22/21 Julia Salzman Splicing at single cell resolution  
1/15/21 David Lipman Genomics for Food Safety & A resource for studying short term evolution  
1/15/21 Alex Colville Dissecting cellular senescence with genetic screens  
12/4/20 Nathan Abell The Landscape of High-Resolution Allele-Specific Expression in the eGTEx Consortium and an Ovarian Cancer Cohort  
12/4/20 Doug Vollrath Assisted Living in the Outer Retina  
11/20/20 Hannah De Jong Tying human and viral genomic variation to disease phenotypes  
11/20/20 Hua Tang The Genetics of Protein Abundance in Human Tissues  
11/13/20 Jin Billy Lli RNA Editing and Innate Immunity  
11/13/20 Kathryn Ribay Moving from antiracist talk to antiracist action: Research-backed strategies from education  
10/30/20 Maria Barna Ribosomes in gene regulation: controlling the diversity of proteins made in specific cells, tissues, and organisms  
10/30/20 Kay Kobak Generating and Harnessing a Robust Placental Epigenome  
10/16/20 Jennifer Doherty Mental Health and Wellness in Grad School  
10/16/20 Graham Irwin Searching Beyond the Streetlamp: Recurrent Repeat Expansions in Cancer Genomes  
10/9/20 Nathan Abell The Landscape of High-Resolution Allele-Specific Expression in the eGTEx Consortium and an Ovarian Cancer Cohort  
10/9/20 MaryAnn Campion Increasing Engagement and Inclusion: Lessons from the Genetic Counseling field  
10/2/20 Abbey Thompson Genetics at The Tech Interactive: Informal education during a pandemic  
10/2/20 Theo Susanto Rapid enrichment of ribosome-associated proteins across cell types, tissues, and species  
9/18/20 Anne Brunet Single cell analysis of inflammation and immune cell infiltration in the aging brain  
9/18/20 Kevin Van Bortle A switch in RNA polymerase III identity underlies dynamic transcription potential during cellular differentiation  
8/21/20 Akshay Sanghi Addressing Racism in the STEM Training Pipeline by  
Boosting the Transition to Graduate School
8/21/20 Sedona Murphy Is chromatin structure functional? Understanding polycomb-mediated silencing at Hox genes  
8/21/20 Katelyn McKown Divergent roles of stomatal identity gene FAMA in Arabidopsis  and Brachypodium stomatal development  
8/14/20 Joseph Yracheta Civil Engagement and Big Data Research Is Different in Native Nations. How Tribal Repositories Can Potentially Broker Vital Partnerships  
7/31/20 Nicholas Hughes Scalable Cas12a-based Single Cell Barcoding using Machine Learning  
7/31/20 Kyomi Igarashi Investigation of Species-Specific Cellular Processes During Development  
7/31/20 Olena Zhulyn Rapid remodeling of the translatome underlies wound healing and regeneration  
7/24/20 Ben Siranosian  Transmission of pathogens in the microbiome of immunocompromised patients  
7/24/20 Gabe Rosenfield Pre-Contact Non-Self Recognition in Neurospora crassa  
7/24/20 Miranda Stratton & Latishya Steele Addressing Anti-Black Racism and Creating a Community Committed to Racial Justice  
7/17/20 Nicole Gay Acute endurance exercise induces widespread transcriptional changes across tissues”  
7/17/20 Akshay Sanghi A chromatin basis for protein-transcript correlation in human cancers  
7/17/20 Maryam Yousefi Determining genetic drivers of oncogene-negative lung adenocarcinomas  
7/10/20 Adam Reeves Chromatin Accessibility During Killifish Diapause: A Window into Regulatory Elements Controlling Function and Evolution.  
7/10/20 Yinnian Feng Screening T cell-antigen interactions with BATTLES: new tales from new tools  
6/26/20 Jennifer Doherty Genetic strategies to prevent the emergence of antiviral drug resistance  
6/26/20 Adele Xu Functional characterization of ribosomal protein gene copies  
6/19/20 Rebecca Culver Colons or semi-colons? Punctuating the composition, function, & dynamics of the gut microbiota  
6/19/20 Kelsey Fryer Dissecting the role of non-coding RNAs at the centromere  
6/5/20 Alex Kern Identifying Selection Affecting the Late Ergosterol Biosynthesis Pathway in Yeast  
6/5/20 Kévin Contrepois Molecular Choreography of Acute Exercise  
5/29/20 Matthew Buckley Single cell RNA-seq clocks quantify aging & rejuvenation strategies in the brain  
5/29/20 Stephanie Nevins Profiling cellular and genetic heterogeneity in colorectal precancer  
5/22/20 Binbin Chen Computationally identify potential SARS-CoV-2 epitopes and immune evasion  
5/22/20 Alex Colville High-throughput approaches to dissect cellular senescence  
5/15/20 Ben Ober-Reynolds Untangling alopecia with single-cell transcriptomics and chromatin accessibility”  
5/15/20 Laura Donohue Leveraging genome-wide mapping of regulatory landscapes to identify combinatorial transcription factor modules in health and disease  
5/8/20 Robert Coukos High-throughput investigation of protein proximity and protein-protein interaction with a light-gated transcriptional reporter  
5/8/20 Olivia Mae de Gode Annotating long non-coding RNAs through gene expression pattern  
5/1/20 Alissa Severson Population genetics of the Muwekma Ohlone: comparing ancient and modern sample  
5/1/20 Josh Tycko High-throughput discovery and characterization of human transcriptional effector domains  
4/24/20 Aparna Rajpurkar Leveraging deep learning to connect super-resolution DNA traces to transcription  
4/24/20 John Gorzynski Genetic etiologies of fibrosing cardiomyopathy in great apes  
4/17/20 John Gorzynski Genetic etiologies of fibrosing cardiomyopathy in great apes  
4/17/20 Ragini Phansalkar Vascular development in the fetal human heart  
4/10/20 David Yao  Mapping enhancer-promoter interactions with phenotype-driven CRISPR screens  
4/10/20 Nasa Sinnott-Armstrong GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background  
4/3/20 Albert Hinman VDSB-3 Cooperates with DSB-1 and DSB-2 to Promote Meiotic Double-Strand Break Formation  
4/3/20 Roy Ang Investigating epistasis among genetic polymorphisms with single-nucleotide resolution  
2/28/20 Kristen Wells Combined Transient Ablation and Single Cell RNA Sequencing Resolves Thymic Epithelial Cell Development  
2/28/20 Le Cong Single-Cell Genetic Barcoding and Decoding to Probe Cancer Evolution  
2/21/20 Nathan Abell Functional Consequences of Rare Genetic Variation on Gene Expression and Splicing in the GTEx Consortium  
2/21/20 Monther Abu-Remaileh The emerging Roles of the Lysosome In Metabolic Homeostasis  
1/24/20 Wenyu Zhou Defining Ageotypes for Personal Aging Assessment and Intervention  
1/24/20 Jesse Engreitz Activity-by-Contact Model for Enhance-Promoter Regulation from thousands of CRISPR Perturbation  
1/17/20 Tyler Shimko Building a Computational Toolkit to Expedite Protein Engineering  
1/17/20 Brayon Fremin Studying Translation and Identifying Small Proteins in the Microbiome  
12/13/19 Nikki Teran Making Sense of Nonsense: Interpreting Nonsense Mediated Decay Across Individuals and Tissues  
12/13/19 Mike Bassik Development of new CRISPR/Cas9-based Tools to Identify Cancer Drug Targets and Mechanisms of Phagocytosis  
12/6/19 Siming Zhang Integrated Analysis of Gene Expression, DNA Methylation and Chromatin Accessibility in Human Induced Neurons with the 15q13.3 Microdeletion  
12/6/19 Andrew Fire What thy memory can contain: Adventure in the investigation of cellular memory  
11/8/19 Hannah De Jong Deep mutational scanning to find cardiac disease gene variants  
11/8/19 Ami Bhatt Monitoring Microbial Chatter  
11/1/19 Robin Yeo Chromatin dynamics & cell migration changes during neural stem cell aging  
11/1/19 Mark Kay Capsid engineering for enhanced gene transfer and genome engineering in humans”  
8/10/19 Albert Hinman Genomes are made to be broken  
8/10/19 David Gennart Identifying a Chromatin Signature of CAR T Cell Exhaustion  
8/10/19 Nikki Teran Using Allele Specific Expression for Rare Disease Diagnostics  
6/7/19 Rui Tang G-BaToN: a glowing cell interaction report system  
6/7/19 Qin Lin Genetic Mapping of A-to-I RNA Editing in Human Tissues Links Population Variation and Autoimmune Diseases  
5/31/19 Roy Ang Investigating genome-wide epistasis in single nucleotide variants across differentially adapted S. cerevisiae strains  
5/31/19 Massa Shoura Chasing Genome Dynamics Through Time and Space  
5/24/19 Albert Hinman The Role of DSB-3 in Promoting and Regulating Meiotic Double-Strand Break Formation  
5/24/19 Kyuho Han Genome-wide CRISPR screens in lung cancer spheroids identify 3D growth specific cancer vulnerabilities  
5/17/19 Theo Susanto Rapid enrichment of ribosome-associated proteins across cell types, tissues, and species  
5/17/19 Tao Sun Cytoplasmic RNA editing is required to suppress MDA5-mediated dsRNA innate immunity  
5/10/19 Kristen Lynn Wells Single cell sequencing defines immediate precursor of stable medullary thymic epithelial cell populations  
5/10/19 Nathan Samuel Abell Resolving and Interpreting Highly Linked Non-Coding Genetic Associations in Humans  
5/3/19 Nasa Sinnott-Armstrong The genetic basis of serum and urine laboratory tests  
5/3/19 Kotaro Fujii Decoding the Function of Ribosome Tentacles  
4/26/19 Josh Gruber HAT1 drives a gene-metabolite circuit at the center of chromatin  
4/26/19 Adam Wilkinson Long-Term Ex Vivo Expansion Of Hematopoietic Stem Cells  
4/12/19 Brayon Fremin Validation of structured RNAs in the human gut microbiome  
4/12/19 Tyler Shimko Graph convolutional neural networks: a tool to understand and design molecular interactions  
3/15/19 Hannah De Jong Predicting hypertrophic cardiomyopathy variants by high-throughput mutagenesis  
3/15/19 Siming Zhang Molecular characterization of 15q13.3 microdeletion using an iPSC model  
3/8/19 Robin Yeo The dynamic chromatin landscape of neural stem cell aging  
3/8/19 Jessica Ribado  Illuminating microbial dark matter using long read technologies  
2/22/19 Fiona Tamburini Exploring the gut microbiome and cardiometabolic disease in two South African populations  
2/22/19 Euan Ashley Better diagnosing rare genetic disease  
2/15/19 Evan Boyle Coaxing coessential gene signal from pooled CRISPR knockout screens  
2/15/19 Kelly Ormond RISPR in the news  
2/8/19 Eli Moss Genomes from Metagenomes: New Tools for Complex Microbial Communities  
2/8/19 Michael Cherry Something Old and Something New  
2/1/19 Kimberly Tsui Systematic identification of regulators of antibody-drug conjugate internalization and intracellular trafficking using CRISPR-Cas9 screens  
2/1/19 Jonathan Pritchard Trans eQTLs drive architecture of human complex traits  
1/25/19 Keyla Badillo Current Issues in Preeclampsia and Population Genetics  
1/25/19 Minx Fuller How to rapidly switch cell types:  Developmentally regulated alternative 3’ end processing of nascent transcripts controls the menu of proteins expressed at consecutive steps during differentiation  
1/25/19 Keyla Badillo Current Issues in Preeclampsia and Population Genetics  
1/25/19 Tang Hua Harmonizing genetic ancestry & self-identified race/ethnicity in multi-ethnic biobanks  
1/18/19 Billy Li ADAR RNA editing: innate immune evasion and transcriptome engineering  
1/18/19 Minx Fuller How to rapidly switch cell types by alternative 3’ end processing of nascent transcripts  
1/13/19 Michael Sikora Selecting and sequencing clonally expanded T cells  
1/13/19 Hiro Nakauchi Xenogeneic barrier in interspecies chimera formation  
12/7/18 Han Sun CDK-RAB fusion and activation in cancers  
12/7/18 Anshul Kundaje Interpretable deep learning models of high-resolution transcription factor binding profiles (ChIP-nexus/exo) reveal the diversity of functional combinatorial cis-regulatory sequence grammars  
11/9/18 Matthew J. McCoy The Role of Gene Complexity in the Evolution and Function of Nervous Systems  
11/2/18 Julien Sage Generation and maintenance of intra-tumoral heterogeneity in SCLC  
11/2/18 Alistair Boettiger Visualizing DNA folding and transcription in embryogenesis  
10/5/18 Karla Kirkegaard Dominance, Drugs and Viruses  
9/28/18 Arend Sidow The magic of diploid genome reconstruction for detection of structural variation  
9/28/18 Phillip Cleves Using Transcriptomics and Reverse Genetics to Understand Cnidarian-Dinoflagellate Symbiosis  
8/3/18 Roy Ang From barrel to bedside: Investigating genome-wide epistasis in single nucleotide variants across differentially adapted S. cerevisiae strains   
8/3/18 Nathan Abell Characterizing Regulatory Genetic Variation by Massively Parallel Reporter Assay Across the Allele Frequency Spectrum  
7/20/18 Kristen Wells Single cell sequencing informs stages of thymic cell development  
7/20/18 Cameron Prybol Regulating the Ca-dependent genetic etiology of hypertrophic cardiomyopathy  
7/13/18 Nasa Sinnott-Armstrong USF1 modulates chronotype and consolidates sleep  
7/13/18 Tyler Shimko Biophysical measurements inform structure- function models of Transcription factor binding specificities