Gene Therapy Clinical Trials
4D-CT-based Ventilation Imaging for Adaptive Functional Guidance in Radiotherapy
To develop and investigate a novel radiotherapy technique for preserving lung function based on a map of lung function.
Stanford is currently not accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- device: Real-time Position Management system
- device: Discovery ST multislice PET/CT scanner
- device: Infinia Hawkeye SPECT/CT gamma camera
- device: Pinnacle3 treatment planning system
- device: SKYLight nuclear camera
- drug: DTPA
- drug: TECHNETIUM TC 99M MAA
Eligibility
Inclusion Criteria:
- Eligible disease(s)/stage(s) AJCC Stage I, II, III or IV lung cancer of any histology
to be treated using radiotherapy will be eligible for this study. Note that we will
carefully consider the inclusion of cases with turbulent flow or greater flow
velocities (Cabahug et al., 1996; Crawford et al., 1990) and COPD cases (Magnant et
al., 2006) due to the impaction of aerosol particles in central airways.
- Allowable type and amount of prior therapy. Any types and amounts of prior therapy
will be allowed for this study.
- Age restriction and/or gender/ethnic restrictions
- Patients must be greater than or equal to 18 years of age.
- There are no gender or ethnic restrictions.
- Life expectancy restrictions - None.
- ECOG or Karnofsky Performance Status
- Not employed. Note that patients will need to be sufficiently healthy to undergo
audiovisual (AV) biofeedback to generate high quality 4D-CT images.
- Requirements for organ and marrow function None.
- Ability to understand and the willingness to sign a written informed consent document.
Exclusion Criteria:
Children (less than 18 years of age), pregnant women, Stanford employees or students, or
prisoners will be excluded from this study.
Ages Eligible for Study
18 Years - N/A
Genders Eligible for Study
All
Not currently accepting new patients for this trial
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Cancer Clinical Trials Office
650-498-7061
Not Recruiting