Gene Therapy Clinical Trials
Specialized Radiation Therapy in Treating Patients With Stage II, Stage III, Stage IV, or Recurrent Non-Small Cell Lung Cancer and Poor Performance Status
RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.
PURPOSE: This phase I trial is studying the side effects and best dose of specialized radiation therapy in treating patients with stage II, stage III, stage IV, or recurrent non-small cell lung cancer and poor performance status.
Stanford is currently not accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- radiation: hypofractionated radiation therapy
Eligibility
DISEASE CHARACTERISTICS:
- Histologically or cytologically confirmed non-small cell lung cancer
- Stage II-IV and/or recurrent disease
- No small cell histology
- Measurable or evaluable disease
- Tumor not amenable to surgical resection
- Tumor not eligible for stereotactic body radiation therapy
- No prior radiotherapy to the region of the study cancer that would result in overlap
of radiation therapy fields
PATIENT CHARACTERISTICS:
- Zubrod performance status 2-4
- Not pregnant or nursing
- Negative pregnancy test
- Fertile patients must agree to use effective contraception
- Must complete all required pretreatment evaluations
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
- More than 1 week since prior chemotherapy or chemoradiation therapy
- No concurrent chemotherapy
- No other concurrent antineoplastic therapy (including standard-fractionated
radiotherapy to the chest, chemotherapy, biological therapy, vaccine therapy, and
surgery) 1 week before, during, and for 1 week after completion of study therapy
Ages Eligible for Study
18 Years - 120 Years
Genders Eligible for Study
All
Not currently accepting new patients for this trial
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Cancer Clinical Trials Office
650-498-7061
Not Recruiting