Inclusion Criteria:

   - 1) Male or non-pregnant/ non-lactating women ≥ 18 years of age

   - 2) Diagnosis of NASH: NAFLD activity score (NAS) of 4 or greater with a score of 1 for
   each of the following (steatosis scored 0-3, lobular inflammation scored 0-3,
   ballooning scored 0-2):

      - Steatosis

      - Lobular inflammation

      - Hepatocyte ballooning 3) Fibrosis (Ishak fibrosis score ≥1 on liver biopsy)
      within 6 months of enrollment with MELD<10, or based on MRE

Exclusion Criteria:

   - Presence of any other form of liver disease, including viral hepatitis, autoimmune
   hepatitis, alcoholic liver disease, genetic causes of chronic liver disease):

   - Subjects with other etiologies of chronic liver disease, such as chronic hepatitis B
   and C; autoimmune hepatitis; and inherited liver disease.

   - ALT>300 U/l

   - Total serum bilirubin ≥ to 1.3 mg/dL (Gilbert's Syndrome patients excepted)

   - International Normalized Ratio (INR) ≥ 1.3

   - MELD>10

   - Serum creatinine >2.0mg/dl

   - Known alcohol abuse or alcohol use disorder:

      - >20 g/day for women

      - >30 g/day for men

   - Active substance abuse

   - Any medical condition that prevents MRE, MR-PDFF

   - Platelet count ≤100//mm3

   - Decompensated cirrhosis

   - Hemoglobin <11 g/dl in females or <12 g/dl in males

   - Presence/history of HCC

   - History of liver transplantation

   - History of bariatric surgery

   - History of inflammatory bowel disease

   - History of cardiovascular disease, long QT syndrome.

   - Subjects who have participated in investigational drug trials and took any
   investigational drugs within 60 days prior to the first dose of Idebenone. History of
   receiving other investigations drug within 30 days prior to enrollment

   - Any concerns regarding compliance by enrolling physician