Clinical Trials
OVERVIEW
The Division of Gastroenterology and Hepatology conducts clinical trials on novel therapeutics for various liver diseases, bringing promising and innovative therapies to our patients.
Our team has extensive experience selecting the right patients for the right trials.
Clinical trials are an important part of the research involved in developing new medical treatments. Enrolling in a clinical trial enables participants to take an active role in their own health care, gain entrance to new research, and contribute to medical science.
Participants must meet specific criteria to be eligible for enrollment in a clinical trial. Some research studies seek participants with illnesses or specific conditions to be studied in the clinicaltrial, while others ask for healthy participants.
CURRENT AND ONGOING TRIALS
Effects of an Intermittent Reduced Calorie Diet on Crohn's Disease
The purpose of this study is to see how an Intermittent Calorie Reduced Diet (IRCD) that mimics fasting effects inflammation in patients with mild to moderate Crohn's disease (CD). The diet may allow users to receive the benefits of fasting while also being able to enjoy food (the ingredients of which are GRAS (generally recognized as safe) by the Food and Drug Administration (FDA). Research on dietary interventions and CD are very limited. Diets that mimick fasting have been studied with support of the National Institute of Health and published in leading journals. This research investigates whether markers of inflammation decrease and/or quality of life increases after five-day periods of the IRCD, and may provide rationale for its use to treat CD.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- other: Intermittent Reduced Calorie Diet (IRCD)
Eligibility
Inclusion Criteria:
- Mild to moderate Crohn's disease (CDAI score 151-450)
- Between the ages of 18-70 (inclusive)
Exclusion Criteria:
- Women who are pregnant, nursing or expect to be pregnant
- Individuals allergic to nuts
- Individuals with a body mass index (BMI) lower than 18
- Individuals diagnosed with a serious medical condition (unless approved in writing by
a physician)
- Individuals who have been severely weakened by a disease or medical procedure
- Individuals who are taking medication which may not be safely consumed with a calorie
restricted diet
- Individuals with diabetes who are taking anti-diabetic drugs associated with risk of
hypoglycemia
- Individuals with more than mild-moderate cardiovascular disease or life-threatening
cancer (as determined by patient's physician) unless approved by a physician
- Individuals with history of severe cardiac disease (particularly uncompensated
congestive heart failure NYHA grade 2 or more or LVEF < 40%)
- Individuals with a history of syncope
- Individuals with dietary needs incompatible with the IRCD meal plan
- Individuals with liver or kidney disorders that may be affected by very low glucose
and protein content of the diet
- Patients on a calorie restricted diet will also be excluded
- Patients with relevant prior gastrointestinal surgery and consequences such as short
bowel syndrome, ostomy of small or large intestine,total colectomy, proctocolectomy,
ileoanal pouch will be excluded (not excluded are patients with resection of terminal
ileum, resection of short strictures of the small intestine, hemicolectomy).
Ages Eligible for Study
18 Years - 70 Years
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Touran Fardeen
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