Functional Genomics of DSB Repair Processes

The Frock Lab studies the genome-wide fate of various forms of double-stranded DNA breaks (DSBs). Projects in the lab use a combination of genetics, molecular biology, next generation sequencing, and bioinformatics to uncover DSB mechanisms and to reveal a deeper understanding of DSB repair processes.

The long term goal of the Frock lab is to develop novel cancer diagnostics/therapeutics and genome editing approaches.

Visit frocklab.com for more information


Latest News in the Frock Lab

Check out the latest work from the lab on bioRxiv describing how the DNA Damage Response works with alternative end joining to suppress microhomology-mediated end joining! -- April 2024

Congratulations to Jinglong for his publication on DNA-PK kinase inhibition and impact to chromosome translocations in Nucleic Acids Research! -- February 2024

Welcome to Carrie Truong working on a remote project from St. Joseph Notre Dame! -- November 2023

Congratulations to Jinglong for his published paper on Cas9 cleavage plasticity in the Nature Structural & Molecular Biology! -- October 2023

Welcome, Elvis Lang, to the lab this summer coming from from Case Western Reserve! -- June 2023

Check out the first episode of Science in 5 by Kai Zheng on youtube! -- June 2023

... and more!