Functional Genomics of DSB Repair Processes

The Frock Lab studies the genome-wide fate of various forms of double-stranded DNA breaks (DSBs). Projects in the lab use a combination of genetics, molecular biology, next generation sequencing, and bioinformatics to uncover DSB mechanisms and to reveal a deeper understanding of DSB repair processes.

The long term goal of the Frock lab is to develop novel cancer diagnostics/therapeutics and genome editing approaches.

Visit frocklab.com for more information


Latest News in the Frock Lab

Welcome Garima Chaturvedi, PhD to the Frock lab! -- March 2025

Check out the latest work from the lab on bioRxiv describing how the DNA Damage Response works with alternative end joining to suppress microhomology-mediated end joining! -- April 2024

Congratulations to Jinglong for his publication on DNA-PK kinase inhibition and impact to chromosome translocations in Nucleic Acids Research! -- February 2024

Welcome to Carrie Truong working on a remote project from St. Joseph Notre Dame! -- November 2023

Congratulations to Jinglong for his published paper on Cas9 cleavage plasticity in the Nature Structural & Molecular Biology! -- October 2023

Welcome, Elvis Lang, to the lab this summer coming from from Case Western Reserve! -- June 2023

Check out the first episode of Science in 5 by Kai Zheng on youtube! -- June 2023

... and more!