AI to Support Effective Treatment Implementation

The Center for Responsible and Effective AI Technology Enhancement of Treatments for PTSD (CREATE) is a new National Institute of Mental Health-funded multidisciplinary center that develops and evaluates LLM-based tools to support evidence-based mental health treatment implementation.

This recent article provides an overview of CREATE's goals and plans.

Stay tuned for more details!

Click here to learn about Stanford's AI for Mental Health initiative.

Click here to learn about the Stanford Mental Health Technology and Innovation Hub.

Click here to watch the AI4MH Seminar featuring Dr. WIltsey Stirman and to read the 2025 Forbes Article on Stanford's AI initiatives. 

A selection of recent papers in this area from our team:

OSF Preprints | Current Real-World Use of Large Language Models for Mental Health

Scholich, T., Barr, M., Wiltsey Stirman, S., & Raj, S. (2025). A comparison of responses from human therapists and large language model-based chatbots to assess therapeutic communication: Mixed methods study. JMIR Mental Health12, e69709. https://doi.org/10.2196/69709

Stade, E. C., Eichstaedt, J. C., Kaysen, D. L., Salesha, A., Greenberger, A., Singhvi, S., & Stirman, S.W. (2025). TherapyTrainer: Using AI to train therapists in written exposure therapy, Cognitive and Behavioral Practice. https://www.sciencedirect.com/science/article/abs/pii/S1077722925000495

Stade, E. C., Eichstaedt, J. C., Kim, J. P., & Stirman, S. W. (2025). Readiness evaluation for artificial intelligence-mental health deployment and implementation (READI): A Review and proposed framework. Technology, Mind, and Behavior6(2). https://doi.org/10.1037/tmb0000163

Stade, E. C., Stirman, S. W., Ungar, L. H., Boland, C. L., Schwartz, H. A., Yaden, D. B., Sedoc, J., DeRubeis, R. J., Willer, R., & Eichstaedt, J. C. (2024). Large language models could change the future of behavioral healthcare: a proposal for responsible development and evaluation. NPJ Mental Health Research3(1), 12. https://doi.org/10.1038/s44184-024-00056-z

Held, P., Stade, E. C., Dondanville, K., & Stirman, S. W. (in press). Generative artificial intelligence in PTSD treatment: Exploring five different use cases. Journal of Traumatic Stress. https://doi.org/10.31234/osf.io/sv5px_v2

Stade, E. C., Eichstaedt, j. C., Kaysen, D., Salecha, A., Greenberger, A., Singhvi, S., & Stirman, S. W. (in press)TherapyTrainer: Using AI to train therapists in written exposure therapy. Cognitive and Behavioral Practice https://doi.org/10.31219/osf.io/wx93m

Stade, E. C., Stirman, S. W., Held, P., Schwartz, H. A., & Eichstaedt, J. C. (in press). Designing clinical psychological AI that reduces suffering: Challenges and technical considerations. https://doi.org/10.31234/osf.io/tjv8p

Articles and policy briefs:

A Blueprint for Using AI in Psychotherapy | Stanford HAI

HAI-Policy-Brief-Responsible-Development-LLMs-Psychotherapy.pdf