Prof. Wendy Fantl, PhD

Assistant Professor (Research) of Urology and by courtesy of Obstetrics and Gynecology

Education: Ph.D. Protein Biochemistry, Rockefeller University

Bio: Wendy Fantl, a Cancer Biologist, is an Assistant Professor in the Department of Urology and by courtesy in Obstetrics and Gynecology at Stanford University School of Medicine. Dr Fantl obtained her Ph. D at Rockefeller University training with Drs. Anthony Cerami, James Manning, and Nobelist Stanford Moore over the course of her graduate studies in Protein Biochemistry. She completed her postdoctoral studies at UCSF with Dr. Lewis ‘Rusty” T Williams where she was one of the first scientists to demonstrate a link between cell surface receptor tyrosine kinases and how they communicate with specific intracellular signaling molecules to alter cellular behavior. This work motivated her to move to the BioTech sector (Chiron Corporation) where she contributed to drug development targeting intracellular signaling molecules. After over a decade at Chiron she was appointed Vice president of Cancer Biology at Nodality, a start-up company focusing on diagnostic tests for leukemias using phospho-flow cytometry. In 2010 she returned to Academia (Stanford) as a Senior Scientist and joined the faculty at the end of 2014. Dr Fantl’s unconventional career trajectory has provided her with many advantages and has enhanced her ability to translate the work from her lab to directly benefit cancer patients.


Postdocs

Antonio Delgado-Gonzalez, PhD

Position: Postdoctoral Fellow

Education: B.Sc. Pharmacy, University of Granada (2013); M.Sc. Molecular Biology, University of Granada (2014); Ph.D. Biomedicine, University of Granada (2019); Postdoctoral Fellow, University of Granada (2019)

Bio: Antonio received his B.Sc. in Pharmacy (2013) and M.Sc. in Molecular Biology (2014) from the University of Granada (Spain). He completed his international Ph.D. in Biomedicine (2019) with excellent cum laude at the University of Granada. His Ph.D. research was focused on the development of nanoparticle-based platforms combined with chemical approaches for cellular and molecular assays. He was a visiting Ph.D. student at the University of Edinburgh (UK) in the laboratory of Prof. Marc Vendrell, and at Stanford University in the laboratory of Prof. Garry P. Nolan. Antonio joined the Fantl Lab in 2020 as a postdoctoral fellow and his project aims at comprehensively understanding the immune tumor microenvironment and its spatial arrangement in ovarian and urologic cancers, through the application of cutting-edge multi-parametric single-cell proteomic technologies (mass cytometry and CO-Detection by indexing (CODEX)). In his free time, he enjoys sports and traveling around the world.

Staff

Ying-Wen Huang, MS

Position: Life Science Research Professional II

Education: B.S. Pharmacy, National Taiwan University; M.S. Pharmacology, National Taiwan University; M.S. Biology, Stanford University

Bio: Ying is a molecular biologist with an extensive knowledge about all aspects of high-dimensional mass cytometry (CyTOF) experimentations, from design to data analysis. She has twenty years of research experience in the fields of cancer biology, immunology, and pharmacology studying the molecular signaling mechanisms that regulate DNA damage response, cell cycle progression, apoptosis, cell proliferation, and lymphocyte/erythrocyte/myeloid cell signaling. 

Her present work is focused on NK cell biology, primary ovarian cancer, and metastatic renal cell carcinoma. She is actively involved in planning and performing clinical studies and uses the multi-parametric single-cell mass cytometry platform to characterize the tumor and immune cell signatures (including phenotypic changes and functional signaling responses) in healthy and patient samples with the aim to identify disease-causing cell subsets and understand their signaling networks. 

Kenyi Donoso

Position: CODEX Technician

Education: Degree in Aircraft Mechanics, Volvo Aero, Stockholm, Sweden

Bio: Kenyi is a lab technician who specializes in CODEX imaging. His expertise covers all aspects of the CODEX pipeline from primary tumor sample processing to tissue microarray construction to image acquisition. He is continually seeking ways to improve the Fantl Lab's approach to CODEX and applies his engineering skillsets (3D printing, metal machining, protocol optimization) to design novel tools, devices, and methods to optimize tissue processing and storage for multiplexed imaging experiments. Currently, Kenyi is working on projects characterizing the tumor microenvironments of HGSOC and RCC with CODEX.

Jacob Bedia

Position: Life Science Research Professional I

Education: B.S. Chemistry and Mathematics, Stanford University (2021)

Bio: Jacob recently graduated from Stanford University with a B.S. in chemistry and mathematics. He is broadly interested in combining high dimensional single cell proteomics with cutting-edge data analyses to address unmet medical needs in the diagnosis and treatment of high grade serous ovarian cancer (HGSOC). During his undergraduate in the Fantl Lab and closely collaborating lab of Prof. Garry Nolan, Jacob participated in several CyTOF and CODEX projects studying colorectal cancer, renal cell carcinoma, and high grade serous ovarian cancer. Additionally, he led several computational projects including parametric modeling of colorectal cancer and tissue image analysis with neural networks. His current work focuses on deeply characterizing the tumor microenvironment of HGSOC with CODEX and revealing novel insights into the relationship between the DNA damage response and platinum-based resistance in HGSOC using CyTOF and network analyses. In his free time, he enjoys exploring the Bay Area with friends and improvising on piano and trombone.