Past Studies
Emotion Regulation in Adolescents with Binge Eating and Purging
A study for girls 14-18 who struggle with binge/purge behaviors (no formal diagnosis is required to participate). The study involves two appointments - one interview and one fMRI scan. Participants are compensated $100.
Recruitment age range: 14-18 years old
Recruitment gender: Female
Family-Based Treatment Training Study
Stanford University is conducting an NIH-sponsored study looking at how to best train therapists in delivering Family-Based Treatment for anorexia nervosa.
Who can participate?
- Therapists that have completed a masters or doctoral training in their field (psychology, psychiatry, family therapy, social work) and are licensed in their respective state
- No reports of malpractice or loss of privileges at relevant clinical institutions
- Have computer/web access for online training and assessments
- No previous 2-day in-person workshop training in FBT
- Able to submit baseline data on weight gain from week 1-4 from a previously treated adolescent with AN they have treated in the last 6 months or alternatively one that they treat within the first 3 months of completing their initial screen.
Trainings
All participants are randomized to one of two trainings:
- Online training which consists of 10 lectures that are self-paced with a maximum of three months to complete with each lecture bundle comprising of short didactic videos that discuss the treatment model and provide mock therapy session video clips (modeling FBT with a typical adolescent AN case), as well as supplementary readings and videotaped role-plays.
- Webinar training which consists of 1-hour weekly webinar lectures over three months. There will be lectures discussing the scientific evidence supporting FBT, how therapists set up treatment for FBT, main interventions used in FBT during each phase, and recorded role-plays illustrating interventions throughout the 3 phases.
Both trainings are followed by post-online expert supervision for a minimum of 1 case and a maximum of 2 cases over the course of 3 months.
Confirming the Efficacy/Mechanism of an Adaptive Treatment for Adolescent Anorexia Nervosa
Currently, the most promising treatment for adolescents with Anorexia Nervosa is Family Based Treatment (FBT). In this study, all participants will receive standard FBT for Anorexia Nervosa administered by trained psychologists free of charge to the family. If participants fail to show sufficient improvement by study parameters by session 4, they will be randomized to receive either FBT + Intensive Parental Coaching (IPC) or FBT as usual. Each patient, regardless of randomization, is offered up to 18 sessions over the course of 9 months. The adolescent will also earn $50 upon completion of the entire study for their participation.
Recruitment age range: 12-18 years of age
Key words: eating disorders, FBT, Anorexia Nervosa
Feasibility of Conducting a Randomized Controlled Trial Comparing Standard FBT and Guided Self-Help FBT for Adolescent Anorexia Nervosa
There is an ongoing study being conducted at Stanford University comparing telemedicine family-based treatment (FBT) to an online guided self-help version of family-based treatment (FBTgsh). This study offers evidence-based treatment to adolescents with anorexia nervosa online and at no cost. All participants will receive one form of family-based treatment (FBT) for Anorexia Nervosa. Prior to starting treatment participants are randomized to participate in either of the following treatments:
- Guided Parental Self-Help Version of FBT (FBTgsh): consisting of 12 30-minute telemedicine treatment sessions with a trained clinician paired with an online platform that contains recorded lessons and resources.
- Telemedicine-based Standard FBT: consisting of 15 1-hour telemedicine treatment sessions with a trained clinician.
Both treatments are over the course of up to 6 months. This is then followed by a 3-month post-treatment assessment. All assessments (Baseline, End of treatment, 3-month post-treatment) are done via teleconferencing as well. Participants receive $35 upon completion of the study. We do not know the feasibility of Guided Self-Help for individuals and we hope to better identify an adequate treatment for those who do not have access to FBT in their communities.
Recruitment age range: 12-18 years of age
Key words: eating disorders, FBT, Telemedicine, Anorexia Nervosa
Food and Brain Study: Emotion and Reward Processing in Binge Eating
Who can participate?
- Women ages 18-35
- No metal in body or mouth hardware
- Able to speak English
- Able to come to 2 1-2-hour visits at Stanford
The study includes 2 appointments lasting between 1 and 2 hours, and you will be paid $50-150 for your participation.
Familial Aggregation Study of Anorexia, OCD, and Cognition
Our five-year NIH sponsored study examines cognitive functioning of adolescent females with anorexia nervosa as compared to healthy controls, through neuropsychological testing and functional Magnetic Resonance Imaging (fMRI). If you would like to participate in this exciting new research, you and your family will come to Stanford for a battery of neuropsychological testing.
Each participant and their family members will complete a series of assessments that span approximately 2 – 3 hours. In addition, female participants with anorexia, their sisters, and age matched healthy controls will undergo an fMRI scan during which they will play cognitive computer games.
To be eligible as a participant with OCD, you must:
- Be a female between the ages of 12– 19
- History of OCD
If you are traveling from a distance, we will reimburse your travel expenses including flights and hotels.
To be eligible as a participant with a history of anorexia, you must:
- Be a female between the ages of 12 – 19
- Have a sister within three years of your age.
- History of Anorexia Nervosa
To be eligible as a participant as a control:
- Be a female between the ages of 12-19
- No psychiatric history
Each participating family member is compensated $75 for completing the assessments; participants who are scanned will be paid $150-$180.
Parent-Based Prevention Research Study for Mothers with Eating Disorders
This is a study examining the feasibility and acceptability of a preventive intervention program designed to improve child feeding in families in which the mother has an eating disorder. Participants will be randomly selected to receive one of two different treatment arms. Each treatment extends over 16 weeks period and consists of 12 sessions.
Who can participate?
- Adult mothers with children between the ages of 1 and 5 years old
- Current diagnosis of Anorexia Nervosa, Bulimia Nervosa, or Binge Eating Disorder
- Living with a partner
- Medically stable for outpatient treatment
Family Based Treatment Training for Therapists
Interested in being trained and supervised in Family Based Treatment for adolescent Anorexia Nervosa? Stanford University and the University of California, San Francisco are conducting a research study funded by the National Institute of Health to explore the best way to provide high quality training to busy therapists. Training will be online and supervision will be provided by a Family Based Treatment expert free of charge.
Qsymia (phentermine-topiramate) to Reduce Binge Eating/Purging in Patients with Binge Eating Disorder and Bulimia Nervosa
This study aims to test the efficacy of an FDA approved drug for obesity, Qsymia, for reducing symptoms of binge eating and/or purging in participants with binge eating disorder and bulimia nervosa, compared to a control medication. All study participants will receive the study medication-- either in the first half of the study or in the second half of the study. Neither you nor members of the research team will know the order in which you receive them until the end of the trial. Medication is provided at no cost and the study is expected to take up to 6 months.
Who can participate?
- Men and women aged 18-60 with current symptoms of binge eating and/or purging
For general information regarding questions, concerns, or complaints about research, research related injury or the rights of research participants, please call (650) 723-5244 or toll-free 1-866-680-2906, or write to the Administrative Panel on Human Subjects in Medical Research, Administrative Panels Office, Stanford University, Stanford, CA 94305-5401.