Welcome to the David Lewis Lab

The David Lewis Lab is part of the Department of Pediatrics, Division of Allergy, Immunology & Rheumatology, the Sean N. Parker Center for Allergy and Asthma Research, the Stanford Immunology Program and the Immunology, Transplantation and Infection Institute (ITI) at Stanford University. We gratefully acknowledge major support of the lab by the Naddisy Foundation Professorship in Pediatric Food Allergy, Immunology, and Asthma and the Kruzn’ for a Kure Foundation.   

Lab research interests include using CRISPR homologous-directed repair genomic DNA editing to study disease mechanisms and develop therapy for very rare inborn errors of immunity, such as Schimke Immuno-Osseous Dysplasia (SIOD), using non-gene editing types of CRISPR for the treatment of respiratory viral infections and severe allergic diseases,  and defining normal and perturbed mechanisms of human T-cell development in the fetus, neonate, and young infants.