April 23-24, 2018
Li Ka Shing Conference Center
Advances in research and technology now afford us the unique opportunity to develop and test novel diagnostics and therapeutics. This conference takes advantage of the collective experience and expertise of our speakers in drug discovery. A broad range of policy, research, and venture topics are covered.
Speakers
Howard Bauchner, MD
Editor in Chief, JAMA
Paul Berg, PhD
Robert W. And Vivian K. Cahill Professor of Cancer Research, Emeritus
Robert Bradway
CEO, Amgen
Amy Chang
CEO, Accompany
Jennifer Cochran, PhD
Shriram Chair of Bioengineering, Stanford
Edgar Engleman, MD
Professor of Pathology and Medicine (Immunology and Rheumatology)
Ken Frazier
CEO, Merck
Kathleen Giacomini, PhD
Professor, Co-Director UCSF-Stanford Center of Excellence in Regulatory Sciences and Innovation
Gary Gibbons, MD
Director, NHLBI
Wende Hutton
General Partner, Canaan
Joe Jimenez
Former CEO, Novartis
John Keaney, MD
Associate Editor, NEJM
Paula Kiberstis, PhD
Senior Editor, Science
Brian Kobilka, MD
Helene Irwin Fagan Chair in Cardiology, Stanford
Maria Millan, MD
President and CEO, CIRM
Lloyd Minor, MD
Carl and Elizabeth Naumann Professorship for the Dean of the School of Medicine | Professor of Otolaryngology—Head & Neck Surgery
Joao Monteiro, MD, PhD
Chief Editor, Nature Medicine
Robert Robbins, MD
President, University of Arizona
Hugh Rosen, MD, PhD
Scripps Institute
ActiveX Biosciences
Brent Saunders
CEO, Allergan
George Scangos, PhD
CEO & Director, VIR
Kevan Shokat, PhD
Prof and Chair, Dept of Cellular and Molecular Pharmacology, UCSF | Prof, Dept of Chemistry, UC Berkeley
Ram Shriram
Founder & Managing Partner, Sherpalo Ventures
Patrick Soon-Shiong, MD
Chair of NantWorks, LLC, Executive Director of Wireless Health Institute at UCLA
Marc Tessier-Lavigne, PhD, FRS, FRSC
President and Bing Presidential Professor
Roy Vagelos, MD
Retired Chairman & CEO, Merck & Co., Inc. and Chairman of the Board, Regeneron Pharmaceuticals, Inc.
Sanford Weill
Chairman Emeritus of Citigroup and Philanthropist
Janet Woodcock, MD
Director, Center for Drug Evaluation and Research, FDA
Day 1 | April 23, 2018
Welcoming Remarks and Introduction
Joseph Wu, MD, PhD | Director, Stanford Cardiovascular Institute
Lloyd Minor, MD | Dean, Stanford School of Medicine
David Entwistle | CEO, Stanford Health Care
Dennis Lund, MD | Chief Medical Officer, Lucille Packard Children’s Hospital Stanford
Opening Keynote
Brian Kobilka, MD | "Structure-based Approaches for G Protein Coupled Receptor Drug Discovery"
Q & A Session
Academic Drug Discovery Process
Session Chairs and Moderators: Janet Woodcock, MD, and Joseph Wu, MD, PhD
Kathleen Giacomini, PhD | "Regulatory Science in Academia: Advancing drug development"
Kevan Shokat, PhD | "Chemical Tricks for Drugging the Undruggable"
Hugh Rosen, MD, PhD | "Intelligent Intervention: Ozanimod from Hit to NCE at Scripps"
Edgar Engleman, MD | "Treating Disease by Manipulating the Immune System"
Panel Discussion
View From the Top
Ken Frazier | "Inventing for Life: the CEO Perspective"
Joe Jimenez | "Outcomes Based Pricing"
Patrick Soon-Shiong, MD | "Patient as the Biological Factory of the Future"
Bob Bradway | "Moving from 'Break/Fix' to 'Predict/Prevent'"
Brent Saunders | "Using the Innovation Ecosystem to Build a Robust Pipeline"
Sanford Weill | "Philanthropy's Vital Role in Partnering with Healthcare"
Panel Discussion
Fireside Chat
Marc Tessier-Lavigne, FRS, FRSC, FMedSci
Lloyd Minor, MD
Q & A Session
Presentation of Lifetime Achievement Award to Roy Vagelos, MD
Introduction: Paul Berg, PhD, and Ken Frazier
Awardee Lecture: Roy Vagelos, MD | "A Career in Drug Discovery"
Day 2 | April 24, 2018
Keynote Address
Kuldev Singh, MD | Introduction
Janet Woodcock, MD | "Changes on the Horizon for the New Drug Regulatory Program"
Q & A Session
Funding Agency Perspectives
Session Chair and Moderator: Joseph Wu, MD, PhD
Gary Gibbons, MD | "Charting Our Future Together: Advancing Discovery Science for Public Health Impact"
Maria Millan, MD | "CIRM: Acceleration through Partnership"
Q & A Session
Publishing Drug Discovery
Session Chairs and Moderators: Sanjay Malhotra, PhD, and Jennifer Cochran, PhD
Howard Bauchner, MD | "Evolving Issues in Medical Journalism"
John Keaney, MD | "Editorial Considerations in the Evaluation of New Therapies"
Paula Kiberstis, PhD | "Drug Discovery and Science: What's behind the Curtain?"
Joao Monteiro, MD, PhD | "Transparency and Reproducibility in Science: How Journals Can Help"
Round Table Discussion
Starting Up
George Scangos, PhD | "Transitioning from Big Pharma to Startup"
Shark Tank-style Panel featuring:
Roy Vagelos, MD
George Scangos, PhD
Ram Shriram
Robert Robbins, MD
Amy Chang
Wende Hutton
Closing Remarks / Poster Prize Award Announcement
Organizers
Joseph C. Wu, MD, PhD
Director, Stanford Cardiovascular Institute
Simon H. Stertzer, MD, Professor
Department of Medicine (Cardiology) & Radiology
Sanjay V. Malhotra, PhD
Associate Professor (Research) of Radiation Oncology (Radiation and Cancer Biology) and of Radiology (Molecular Imaging Program at Stanford)
Mark Mercola, PhD
Professor of Medicine (Cardiovascular)
Chaitan Khosla, PhD
Wells H. Rauser and Harold M. Petiprin Professor in the School of Engineering and Professor of Chemistry and, by Courtesy, of Biochemistry
Kuldev Singh, MD
Professor of Ophthalmology at the Stanford University Medical Center
Katy Claiborn, PhD
Grants Writer, Cardiovascular Institute Operations
Supported by
