ATVB In Focus: Pioneering Vascular Bioengineering with Dr. Ngan Huang
by Mary Sheridan Bilbao, PA-C, MPAS
June 1, 2024
Ngan Huang, PhD, Associate Professor of Cardiothoracic Surgery at the Stanford School of Medicine, was recently invited to contribute to the "ATVB In Focus Series" by the journal Arteriosclerosis, Thrombosis, and Vascular Biology. This series, which aims to bridge the gap between vascular biology and bioengineering, selected Dr. Huang as the guest editor for its March 2024 edition titled "Mechanics, Matrix, Bioengineering and the Cardiovascular System: Damage to Repair."
Under this focused area, Dr. Huang authors the review article, "Bioengineering Cell Therapy for Treatment of Peripheral Artery Disease." She highlights advances in bioengineering strategies, such as 3-D bioprinting and immunomodulatory biomaterials, that can be applied to the treatment of peripheral artery disease (PAD), and then discusses the challenges and future directions in implementing these bioengineering strategies.
Dr. Huang directs the Cardiovascular Tissue Engineering Laboratory, where she and her team are developing new therapies in tissue engineering and regenerative medicine to treat cardiovascular and musculoskeletal diseases.
In particular, she researches the treatment of PAD, a circulatory condition in which narrowed blood vessels reduce blood flow to the limbs, leading to tissue ischemia. Using biomaterials strategies, she aims to study the potential use of stem cell-derived endothelial cells to survive and restore blood flow in PAD.
Her research was highlighted on the cover of this March 2024 issue of ATVB. (Image shown: Atomic force microscopy of spatially nanopatterned collagen for directing vascular behavior).
Recently, the ATVB journal has seen a surge in reader and article submissions related to vascular bioengineering. The focused series highlights Dr. Ngan's expertise in the rapidly evolving field of bioengineering, allowing readers to gain insights into how bioengineering principles are being applied to understand and treat cardiovascular diseases.
Read the "ATVB In Focus Series" review article here.