Center News

LeBlanc, E. S., Zhang, S., Hedlin, H., Clarke, G., Smith, N., Garcia, L., Hale, L., Hery, C. B., Liu, S., Ochs-Balcom, H., Phillips, L., Shadyab, A. H., & Stefanick, M. (2023). Sleep Characteristics are Associated with Risk of Treated Diabetes Among Postmenopausal Women. The American journal of medicine, S0002-9343(23)00766-0. Advance online publication. https://doi.org/10.1016/j.amjmed.2023.12.011

Yamaguchi, H., Murphy, K. R., Fukatsu, N., Sato, K., Yamanaka, A., & de Lecea, L. (2023). Dorsomedial and preoptic hypothalamic circuits control torpor. Current biology : CB, 33(24), 5381–5389.e4. https://doi.org/10.1016/j.cub.2023.10.076

Angelakos, C. C., Girven, K. S., Liu, Y., Gonzalez, O. C., Murphy, K. R., Jennings, K. J., Giardino, W. J., Zweifel, L. S., Suko, A., Palmiter, R. D., Clark, S. D., Krasnow, M. A., Bruchas, M. R., & de Lecea, L. (2023). A cluster of neuropeptide S neurons regulates breathing and arousal. Current biology : CB, 33(24), 5439–5455.e7. https://doi.org/10.1016/j.cub.2023.11.018

Congratulations to Dr. Chinyere Agbaegbu Iweka on this new funding award from the National Institute of Neurological Disorders and Stroke.

Elliott, J. E., Bryant-Ekstrand, M. D., Keil, A. T., Ligman, B. R., Lim, M. M., Zitser, J., During, E. H., Gagnon, J. F., St Louis, E. K., Fields, J. A., Huddleston, D. E., Bliwise, D. L., Avidan, A. Y., Schenck, C. H., McLeland, J., Criswell, S. R., Davis, A. A., Videnovic, A., Lee-Iannotti, J. K., Postuma, R., … for North American Prodromal Synucleinopathy (NAPS) Consortium (2023). Frequency of Orthostatic Hypotension in Isolated REM Sleep Behavior Disorder. Neurology, 101(24), e2545–e2559. https://doi.org/10.1212/WNL.0000000000207883

Manber, R., Simpson, N., & Gumport, N. B. (2023). Perspectives on increasing the impact and reach of CBT-I. Sleep, 46(12), zsad168. https://doi.org/10.1093/sleep/zsad168

Specht, A., Kolosov, G., Cederberg, K. L. J., Bueno, F., Arrona-Palacios, A., Pardilla-Delgado, E., Ruiz-Herrera, N., Zitting, K. M., Kramer, A., Zeitzer, J. M., Czeisler, C. A., Duffy, J. F., & Mignot, E. (2023). Circadian protein expression patterns in healthy young adults. Sleep health, S2352-7218(23)00240-1. Advance online publication. https://doi.org/10.1016/j.sleh.2023.10.005

We’ve all dealt with nightmares at some point, but what causes them to return? Learn more about the theories behind recurring nightmares and how they can be treated. Rafael Pelayo, clinical professor of psychiatry and behavioral sciences, provides comment.

Roth, T., Thorpy, M. J., Kushida, C. A., Horsnell, M., & Gudeman, J. (2023). Once-nightly sodium oxybate (FT218) improved symptoms of disrupted nighttime sleep in people with narcolepsy: a plain language summary. Journal of comparative effectiveness research, 12(12), e230133. https://doi.org/10.57264/cer-2023-0133

Di Ianni, T., Morrison, K. P., Yu, B., Murphy, K. R., de Lecea, L., & Airan, R. D. (2023). High-throughput ultrasound neuromodulation in awake and freely behaving rats. Brain stimulation, 16(6), 1743–1752. https://doi.org/10.1016/j.brs.2023.11.014

Ono, T., Nishino, N., Iwai, Y., Iwai, Y., Sakai, N., Kuroki, Y., & Nishino, S. (2023). Eurycoma longifolia (Tongkat Ali) enhances wakefulness during active periods but facilitates sleep during resting periods in C57BL/6 mice. The European journal of neuroscience, 58(11), 4298–4309. https://doi.org/10.1111/ejn.16186

Blum, D. J., Hernandez, B., & Zeitzer, J. M. (2023). Early time-restricted eating advances sleep in late sleepers: a pilot randomized controlled trial. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 19(12), 2097–2106. https://doi.org/10.5664/jcsm.10754

If you wake at night and worry, you're far from alone. But these experts say if you've ever had good sleep, you can get back to it — just steer clear of these misconceptions. Rafael Pelayo, clinical professor of psychiatry and behavioral sciences, provides comment.

Heller, H. C., Herzog, E., Brager, A., Poe, G., Allada, R., Scheer, F., Carskadon, M., de la Iglesia, H. O., Jang, R., Montero, A., Wright, K., Mouraine, P., Walker, M. P., Goel, N., Hogenesch, J., Van Gelder, R. N., Kriegsfeld, L., Mah, C., Colwell, C., Zeitzer, J., … Paul, K. (2023). The Negative Effects of Travel on Student Athletes Through Sleep and Circadian Disruption. Journal of biological rhythms, 7487304231207330. Advance online publication. https://doi.org/10.1177/07487304231207330

Merola, J. F., Chiou, A. S., During, E., Costanzo, A., Foley, P., Alfalasi, A., Gogate, S., Pinter, A., Dodiuk-Gad, R., Simon, D., Tauber, M., Weller, R., Pereyra-Rodriguez, J. J., Ardeleanu, M., Wu, J., & Ozturk, Z. E. (2023). Dupilumab significantly improves sleep in adults with atopic dermatitis: results from the 12-week placebo-controlled period of the 24-week phase IV randomized double-blinded placebo-controlled DUPISTAD study. The British journal of dermatology, 189(6), 685–694. https://doi.org/10.1093/bjd/ljad284

Wickwire, E. M., Collen, J., Capaldi, V. F., Williams, S. G., Assefa, S. Z., Adornetti, J. P., Huang, K., Venezia, J. M., Jones, R. L., Johnston, C. W., Thomas, C., Thomas, M. A., Mounts, C., Drake, C. L., Businelle, M. S., Grandner, M. A., Manber, R., & Albrecht, J. S. (2023). Patient Engagement and Provider Effectiveness of a Novel Sleep Telehealth Platform and Remote Monitoring Assessment in the US Military: Pilot Study Providing Evidence-Based Sleep Treatment Recommendations. JMIR formative research, 7, e47356. https://doi.org/10.2196/47356

Rojo, D., Dal Cengio, L., Badner, A., Kim, S., Sakai, N., Greene, J., Dierckx, T., Mehl, L. C., Eisinger, E., Ransom, J., Arellano-Garcia, C., Gumma, M. E., Soyk, R. L., Lewis, C. M., Lam, M., Weigel, M. K., Damonte, V. M., Yalçın, B., Jones, S. E., Ollila, H. M., … Gibson, E. M. (2023). BMAL1 loss in oligodendroglia contributes to abnormal myelination and sleep. Neuron, 111(22), 3604–3618.e11. https://doi.org/10.1016/j.neuron.2023.08.002

Seasonal affective disorder isn’t just about being sad in winter. It’s a type of depression that has to do with the lack of sunlight in late fall and winter, and self-care treatments can include light therapy. Jason Tucciarone, instructor of psychiatry and behavioral sciences, provides comment.

Erin Gibson’s lab has discovered that the precursor cells to myelin-producing oligodendrocytes are regulated by the circadian system in mice. When that regulation breaks down, the researchers saw abnormal myelination — but also fragmented sleep.

Gerardy, B., Kuna, S. T., Pack, A., Kushida, C. A., Walsh, J. K., Staley, B., Pien, G. W., & Younes, M. (2023). An approach for determining the reliability of manual and digital scoring of sleep stages. Sleep, 46(11), zsad248. https://doi.org/10.1093/sleep/zsad248