Current Lab Members
David N. Cornfield, M.D.
Anne T. and Robert M. Bass Professor of Pulmonary Medicine, Director-Center for Excellence in Pulmonary Biology, Department of Pediatrics and (by courtesy) Surgery, Stanford University School of Medicine
Over the past 20 years, my research program has focused upon basic, translational and clinical research, with a primary focus on lung biology. As an active clinician-scientist, delivering care to acutely and chronically ill infants, I have noted the evolution of chronic lung disease of infancy in terms of disease manifestation, management and epidemiology. Even with dramatic improvements in neonatal care, prematurity dramatically increases the risks of chronic lung disease of infancy, infant morbidity and even mortality. Given our focus on child health and development, our laboratory considers how best to mitigate neonatal and infant morbidity and mortality and embarked on two distinct lines of research in wherein: (i) the primary cause of chronic lung disease infants and children might be prevented, prevention of premature birth; and the fundamental biology of chronic lung disease of infancy. Increasingly high-resolution imaging has greatly facilitated and advanced these undertakings in the neonatal lung. Over the past several years, we have also been increasingly focused on the understanding the molecular, cellular and physiologic underpinnings of uterine quiescence and activation in pregnancy and labor. Imaging that permits spatial resolution of structures deep within tissue will add meaningfully to the physiology, cell and molecular biology we routinely perform and in the creation of animal models and clinical research.
Elizabeth A. Barnes, Ph.D.
Senior Research Scientist
Dr. Elizabeth Barnes is a Senior Research Scientist in the Pediatrics Department at the Center for Excellence in Pulmonary Biology at Stanford University. She received her Ph.D. degree in Biochemistry from the University of California, San Diego; M.S. degree in Chemistry from the University of California, San Diego; and B.A. degree in Chemistry from the University of California, Santa Barbara. Prior to joining Stanford University, Elizabeth was a Senior Post-doctoral Fellow in the Department of Surgery at the University of Washington, Seattle studying the development of lymphangioleiomyomatosis (LAM) and tuberous sclerosis complex (TSC) and a Post-doctoral Fellow in the Department of Biochemistry at the University of California, San Diego studying the development of basal cell carcinoma (BCC) and TSC.
Xibing Che, Ph.D.
Basic Life Research Scientist
I received my PhD degree from Hebrew University of Jerusalem for Molecular Virology and completed post-doc training at Dr. Arvin’s lab at Stanford University. My research area of interest at Dr. Arvin’s lab is the host response and pathogenesis of Human Herpesviruses. I joined Dr. Cornfield lab at 2017, my research focus on epigenetics in individual lung cells at different lung’s developing stages.
Daiana Fornes, Ph.D.
Dr. Daiana Fornes is a postdoctoral research fellow in the Pediatrics Department at the Center for Excellence in Pulmonary Biology at Stanford University. She obtained her MSc in the School of exact and natural sciences at the University of Buenos Aires, Argentina. She obtained her PhD in Biological Sciences in the laboratory of reproduction and metabolism in the school of medicine at the University of Buenos Aires. During her PhD, Daiana assessed the programming of metabolic alterations in the offspring of rats with gestational diabetes (GDM) induced by intrauterine programming. She was involved in the development of a novel model of gestational diabetes (GDM) induced by intrauterine programming of female offspring of pre-gestational diabetic rats. Before joining Stanford University, Daiana was a postdoctoral fellow at the University of Buenos Aires where she explored the programming impact of paternal diabetes on the health of the fetus and offspring using a rat model.
Lihua Ying, Ph.D.
Senior Research Scientist
Dr. Ying is involved in several research projects in the lab, where she has been working on exploring the molecular mechanism responsible for developmental differences intrinsic to pulmonary arterial endothelial cells (PAEC) barrier function, in response to injury, is more well preserved in neonatal, compared to adult lungs. Dr. Ying also focuses on the onset of myometrial contraction prior to the induction of term and preterm labor, specifically, examining the role of micro RNA 203 (miR-203) in the regulation of myometrial TRPV4 during pregnancy in murine models of term and preterm labor, via targeted degradation of TRPV4 RNA transcripts.