©2022 Stanford Medicine
Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone
Recruiting
I'm InterestedTrial ID: NCT04676802
Purpose
In the US, pain management after surgery for surgical treatment of osteoarthritis at the base
of the thumb typically consists of prescription opioids during the early recovery phase.
Given the highly addictive nature of prescription opioids, guidelines are being evaluated by
hand surgeons to reduce opioid use while still maintaining pain control after surgery. A
promising approach is to use non-narcotic medication as the first line of treatment. The
purpose of this study is to demonstrate the efficacy of a combination of non-steroidal
anti-inflammatory drugs (NSAIDs), ibuprofen and acetaminophen, in comparison to a morphine
analogue substance (oxycodone) for pain management in the first 30 days after surgery.
Official Title
Pain Relief After Trapeziectomy Without Opioids: Ibuprofen & Acetaminophen Versus Oxycodone
Stanford Investigator(s)
Amy Ladd, MD
Elsbach-Richards Professor of Surgery and Professor, by courtesy, of Medicine (Immunology & Rheumatology) and of Surgery (Plastic and Reconstructive Surgery)
Eligibility
Inclusion Criteria:
- Undergoing trapeziectomy for thumb osteoarthritis
English proficient,
Exclusion Criteria:
- Pregnancy
Current use of opioids
Concurrent surgeries (ex. trapeziectomy combined with carpal tunnel release)
Inability to complete study forms (education, cognitive ability, mental status, medical
status)
Allergy or intolerance to Ibuprofen, Acetaminophen and/or Oxycodone
Liver or kidney dysfunction, abnormal liver enzymes restricting use of acetaminophen or
ibuprofen
History of chronic heart failure, upper gastrointestinal bleeding or coagulopathy
History of complex regional pain syndrome
Intervention(s):
drug: Opioid capsule
drug: NSAID capsules
Recruiting
I'm InterestedContact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305