Platelet Rich Plasma for Patients With Recurrent Implantation Failure

Inclusion Criteria:

   - All women who have undergone 3 or more embryo (blastocyst stage) transfers without
   establishing a clinical pregnancy or 2 or more euploid embryo transfers without
   establishing a clinical pregnancy, aged 18 - 45, with a normal uterine cavity
   established within 12 months by hysteroscopy or saline infusion sonogram, planning in
   vitro fertilization with an embryo transfer at Stanford Fertility and Reproductive
   Health. The planned transfer must consist of any of the following: a PGS proven
   euploid embryo, a good quality blastocyst from a patient younger than 37, or a donor
   oocyte blastocyst.

Exclusion Criteria:

   - Abnormal uterine cavity, planning in vitro fertilization with use of a gestational
   carrier. patients enrolled in other experimental interventions for RIF will be
   excluded. Patients with only poor quality or cleavage stage embryos.