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Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors
Not Recruiting
Trial ID: NCT03206450
Purpose
This research trial studies saliva, semen, and blood samples to determine effects of
chemotherapy on fertility in osteosarcoma survivors. Study biospecimen samples from
osteosarcoma survivors in the laboratory may help doctors learn whether chemotherapy causes
fertility problems and to learn more about the long term effects.
Official Title
Effects of Modern Chemotherapy Regimens on Spermatogenesis and Steroidogenesis in Adolescent and Young Adult (AYA) Survivors of Osteosarcoma
Stanford Investigator(s)
Eligibility
Inclusion Criteria:
- Received upfront therapies for osteosarcoma, which included cisplatin, (with or
without other agents)
- Patient must have completed cancer treatment >= 2 years prior to study enrollment
- Osteosarcoma survivors without a systemically treated relapse or subsequent malignancy
- Note: History of relapse or second malignancy is permitted if treated with local
therapy only (e.g. surgery, radiation)
- Able to speak, read and write in English, French or Spanish
- All patients and/or their parents or legal guardians must sign a written informed
consent
- All institutional, Food and Drug Administration (FDA), and National Cancer Institute
(NCI) requirements for human studies must be met
Intervention(s):
procedure: Biospecimen Collection
other: Laboratory Biomarker Analysis
other: Questionnaire Administration
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Nancy Sweeters
650-721-4074