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PIEB vs CEI for Labor Analgesia: An MLAC Study
Not Recruiting
Trial ID: NCT02573597
Purpose
Utilizing a 'minimal local analgesic concentration (MLAC) study' design to first determine
the relative potency of Programmed Intermittent Epidural Bolus (PIEB) compared to Continuous
Epidural Infusion (CEI) and secondly to determine the mechanism to explain the potential PIEB
efficacy advantage.
Official Title
Programmed Intermittent Epidural Bolus (PIEB) Compared to Continuous Epidural Infusion (CEI) Relative Efficacy and Mechanism of Efficacy For Labor Anlagesia: A Minimal Local Analgesic Concentration (MLAC) Study
Stanford Investigator(s)
Brendan Carvalho
Professor of Anesthesiology, Perioperative and Pain Medicine (Adult MSD) and, by courtesy, of Obstetrics and Gynecology (Maternal Fetal Medicine)
Eligibility
Inclusion Criteria:
- ASA I & II, Nulliparous and Multiparous, Spontaneous/Induced/Augmented Labor, Early
active labor (cervix <5 cm (if known)), Pain (VPS) > 3, 18-45 years of age
Exclusion Criteria:
- <37 weeks gestation, H/o Cesarean Section, Multiple Gestation, Pre-eclampsia,
Narcotics within 3 hours prior to labor epidural placement, Chronic Pain (as defined
by chronic opiate consumption), Women who are participating in another study that will
impact protocol
Intervention(s):
drug: Bupivacaine
drug: Sufentanil
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Aramina Aksamit, RN
512-287-0594