The Value of Short-term Pain Relief for the Prediction of Long-term Outcome After Cervical or Lumbar Nerve Root Infiltration

Not Recruiting

Trial ID: NCT01945554

Purpose

The purpose if this study is to assess the response to nerve root infiltration therapy in patients with cervical or lumbar disc herniations.

Official Title

The Value of Short-term Pain Relief for the Prediction of Long-term Outcome After Cervical or Lumbar Nerve Root Infiltration

Eligibility


Inclusion Criteria:

   - Symptomatic (pain) one-level cervical (C3-C8) or lumbar (L1-S1) radiculopathy with
   radiological evidence of discal nerve root compression

   - Minimum VAS of 20/100

   - Age between 18 - 70 years

Exclusion Criteria:

   - Multilevel disc herniations with multiple symptomatic nerve root compressions

   - Higher motor deficits (Paresis M 0-3 of a peripheral muscle)

   - Age < 18 or > 70 years

   - Pregnancy

   - Allergic reaction against steroids or local anaesthetic

   - Bleeding disorder (Tc < 100.000/ul, Quick <50%, INR > 1.5, abnormal PTT)

   - Known bleeding diathesis

   - Continued anticoagulants (Warfarin = Marcoumar must be bridged with low- or
   high-molecular heparin; commonly, intake of Aspirin or Clopidogrel is no
   contraindication for infiltration therapy but is routinely paused when possible)

   - Pseudoradicular pain (e.g. in facet arthrosis, iliosacral arthrosis...) - as evaluated
   to the best of the knowledge of the admitting physician and radiologist performing the
   infiltration

   - Osseous spinal or foraminal stenosis

   - Myelopathy

   - Severe scoliosis

   - Active neoplasm

   - History of spinal infection / spondylodiscitis

   - History of spinal surgery or previous infiltration therapy on the currently painful
   segment

   - Rheumatic disease

Intervention(s):

procedure: Cervical nerve root infiltration

procedure: Lumbar nerve root infiltration

drug: Mephamesone

drug: 0.5% bupivacaine (Bupivacain®)

drug: Kenacort®

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305