Randomized Phase II Study Comparing Concise Versus Prolonged Afatinib as Adjuvant Therapy for Patients With Resected Stage I-III NSCLC With EGFR Mutation
This research study is a Phase II clinical trial, which tests the safety and effectiveness of an investigational drug to learn whether the drug works in treating a specific cancer. "Investigational" means that the drug is still being studied. It also means that the FDA has not yet approved afatinib for use in patients. In this research study the investigators are looking to see if taking afatinib after surgery works better when taken over a short period of time, compared to a long period of time.
- drug : Afatinib
Phase: Phase 2
Ages Eligible For Study:
- Pathologically confirmed diagnosis of non-small cell lung cancer with EGFR mutation - Complete surgical resection, pathologic stage IA-B, IIA-B, IIIA-B by AJCC 7th Edition staging criteria - Surgical resection with curative intent was at least 6 months prior to enrollment - At least 3 weeks have passed since completion of adjuvant chemotherapy or radiotherapy