Clinical Trials Directory

Predicting Perioperative Opioid Adverse Effects and Personalizing Analgesia in Children: A Multicenter Pharmacogenetic Study

The purpose of this research study is to identify factors and genes (the DNA material that determines the makeup of the human body) that may be associated with how children respond to pain medication. Specifically, the investigators want to study factors that may be associated with pain sensitivity, morphine requirement after surgery and side-effects from morphine and other pain medications. The investigators expect that the information obtained in this research study will help us to develop more effective, safe, and tailored treatment options in the future.

Stanford is now accepting new patients for this trial. Please contact R J Ramamurthi at for more information.


Phase: N/A


Ages Eligible For Study:

6 Years - 17 Years

Inclusion Criteria

- children 6-17 years of age - ASA physical status 1 and 2 - scheduled for tonsillectomy (T) and tonsillectomy and adenoidectomy (T and A) - Children with obstructive sleep apnea will also be included.

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Contact information

Primary Contact:

R J Ramamurthi

Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305

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