Human Skin Aging: Clinical Parameters and Gene Expression Profiling

Inclusion Criteria:

   - healthy female, age 18 or older,

   - Fitzpatrick type 1 or 2 skin,

   - able to read and understand written consent form,

   - body mass index normal or overweight range,

   - willing to take blood tests and donate skin samples

Exclusion Criteria:

   - pregnant or lactating,

   - history of cosmetic surgery affecting the face,

   - use of prescription anti-aging medications for 2 weeks prior to study,

   - use of dietary supplements for 2 weeks prior to study, use of tanning beds or
   excessive light exposure (>2 hours) in the past 2 weeks,

   - medical conditions which at the discretion of the investigator will have significant
   impact on ability to judge subjects' skin characteristics and age, sunless tanner use
   in past 2 weeks