Clinical Trials Directory

A Phase 1/2A Study of the Safety and Efficacy of Modified Stromal Cells (SB623) in Patients With Stable Ischemic Stroke

The primary purpose of the clinical study is to determine the safety of a modified stem cell SB623 when administered to chronic, stable ischemic stroke patients. A second purpose is to determine whether SB623 might improve stroke symptoms. Chronic, stable ischemic stroke patients must be between 6 and 60 months after their stroke, and with only this one prior stroke, and and with no further improvement from physical therapy.

Stanford is now accepting new patients for this trial. Please contact Maria Coburn at 6507369551 for more information.



  • biological : SB623

Phase: Phase 1/Phase 2


Ages Eligible For Study:

18 Years - 75 Years

Inclusion Criteria

- Documented history of one completed ischemic stroke in subcortical region of MCA or lenticulostriate artery with or without cortical involvement - Between 6 and 60 months post-stroke, and having a motor neurological deficit - No significant further improvement with physical therapy/rehabilitation - Able and willing to undergo computed tomography (CT), magnetic resonance imaging (MRI), and positron-emission tomography (PET) scans of the head

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Contact information

Primary Contact:

Maria Coburn 6507369551

Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305

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