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A Randomized Trial of Moderate Intensity Exercise Training in Patients With Hypertrophic Cardiomyopathy

The long term health and cardiovascular benefits of a regular exercise program have been well-established. National guidelines recommend involvement in moderate aerobic fitness (i.e. walking, bicycling, light jogging, swimming) for patients with hypertrophic cardiomyopathy (HCM). However, data on potential benefits of recreational exercise, useful parameters for risk stratification, and methods of devising individual exercise prescriptions are completely lacking. The specific aims of this study are: 1) to devise a safe moderate intensity exercise training program in patients with HCM, and 2) to determine whether exercise training improves ability to perform activities and tasks, heart size and function, and quality of life in patients with HCM.

Stanford is now accepting new patients for this trial.



  • behavioral : stop exercising

Phase: N/A


Ages Eligible For Study:

18 Years - 80 Years

Inclusion Criteria

1. Ages 18 - 80 years old. 2. Diagnosis of hypertrophic cardiomyopathy, defined by the presence of unexplained left-ventricular hypertrophy (wall thickening) > 13 mm in any wall segment. 3. Exercise 30 minutes, 1 day per week for the previous 3 months. 4. Agreement to be a participant in the study protocol and willing/able to return for follow-up.

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Contact information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Lisa Garrett

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