Clinical Trials Directory

A Phase I/II Trial of Temozolomide and Hypofractionated Radiotherapy in Treatment of Supratentorial Glioblastoma Multiforme

The purpose of this study is to investigate the safety and effectiveness of a combination treatment for glioblastoma multiforme utilizing radiotherapy with the FDA approved chemotherapy drug temozolomide

Stanford is not currently accepting new patients for this trial. You may want to check to see if other locations are recruiting.



  • drug : Temozolomide
  • procedure : Stereotactic Radiosurgery

Phase: Phase 1/Phase 2


Ages Eligible For Study:

18 Years - N/A

Inclusion Criteria

- Histopathologically confirmed newly diagnosed glioblastoma multiforme. Diagnosis must be made by surgical biopsy or excision - The tumor must be supratentorial in location - The planning target volume (tumor plus margin) must measure <= 150 cm^3 in volume - Age >=18 years - Life expectancy of at least 12 weeks - Patient must have adequate organ function to tolerate temozolomide (details in the protocol)

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Contact information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305

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