Clinical Trials Directory

Randomized Double-Blind Study to Evaluate the Dose-Related Efficacy and Safety of Caffeine/Propranolol in the Treatment of Acute Migraine

This is a research study to assess the safety of caffeine/propranolol at different dose levels. We want to find out what effects, good and/or bad, it has on patients and their migraines.

Stanford is not currently accepting new patients for this trial. You may want to check to see if other locations are recruiting.



  • drug : placebo
  • drug : caffeine/propranolol combination tablet

Phase: Phase 2


Ages Eligible For Study:

18 Years - 50 Years

Inclusion Criteria

1. Subject has a minimum 12-month migraine history that the investigator determines meets the International Headache Society (IHS) Migraine Diagnostic Criteria for migraine with or without aura 2. Subject is between 18-50 years of age. 3. Subject experiences an average of 2-8 migraines per month. 4. If on preventive migraine therapy, medication regimen has been stable for 30 days and will remain stable for the duration of participation. 5. Subject is able to communicate adequately and comply with the requirements of the study as determined by the investigator. 6. Subject is able to read and understand the informed consent written in English and voluntarily consents to sign the informed consent form.

External Links

Contact information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
S. Charles Cho
Not Recruiting

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