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Cerebral Function Monitoring in Premature Infants
Not Recruiting
Trial ID: NCT00873847
Purpose
This observational study tests the feasibility of enrolling subjects and obtaining an
amplitude-integrated electroencephalogram (aEEG) within the first 72 hours of life, a second
aEEG recording between 72-168 hours of life, and weekly thereafter up to 36 weeks
post-menstrual age. It will enroll 85-100 infants between 401-1,000 grams birth weight OR
between 23 0/7 and 28 6/7 weeks gestational age born at the 7 participating NICHD Neonatal
Research Network sites.
Official Title
Cerebral Function Monitoring and Brain Injury in Preterm Infants: Correlation With Neuroimaging Abnormalities and Neurodevelopmental Impairment - a Pilot Study
Stanford Investigator(s)
Eligibility
Inclusion Criteria:
- Inborn infants
- Between 401 grams and 1,000 grams inclusive birth weight OR between 23 0/7 and 28 6/7
weeks inclusive gestational age
- Decision to provide full intensive care support
- Less than 72 hours of age
Exclusion Criteria:
- Non-intact skin at the central or parietal regions of scalp
- Presence of known or suspected congenital anomalies, including:
- Congenital central nervous system malformations
- Chromosomal anomalies or multiple congenital anomalies
- Complex congenital heart disease
- Inborn error of metabolism
- Acidosis (pH < 6.8 for > 2 hours)
- Persistent bradycardia [HR < 100 bpm] associated with hypoxia for > 2 hours
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305