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A Prospective, Non-Intervention, Observational Assessment of the Correlation Between Circulating Biomarkers of Fungal Bioburden and Clinical Outcome in the Setting of Invasive Aspergillosis

The purpose of this study is to evaluate the relationship between fungal biomarker levels during anti-fungal therapy and the success of treatment for fungal infection. The primary hypothesis is that over the initial two weeks of anti-fungal therapy, fungal biomarkers from participants with invasive aspergillosis (IA) will be lower for those with a successful clinical outcome compared to those with a failed clinical outcome.

Stanford is not currently accepting new patients for this trial. You may want to check to see if other locations are recruiting.



  • other : No Intervention

Phase: N/A


Ages Eligible For Study:

16 Years - N/A

Inclusion Criteria

- Is 16 years of age or older - Female is either post-menopausal, surgically sterilized, willing to use 2 adequate methods of birth control, or agrees to abstain from heterosexual activity throughout the study - Female of child bearing potential must have a negative pregnancy test - Male is surgically sterilized, agrees to use an adequate method of contraception, or agrees to abstain from heterosexual activity for the duration of the study - Has possible, probable, or confirmed invasive aspergillosis (IA) - Has had a computed tomography (CT) or magnetic resonance imaging (MRI) scan 72 hours prior to initiation of anti-fungal therapy

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Contact information

Primary Contact:

Janice Smith-Williams 6507244155

Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305

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