This is an open label, randomized phase II study designed to evaluate the tolerability and response rate of high-dose and low-dose regimens in patients with advanced cutaneous T-cell lymphoma (CTCL) who have had progressive, recurrent, or persistent disease on or following 2 systemic therapies.

Stanford is not currently accepting new patients for this trial. You may want to check clinicaltrials.gov to see if other locations are recruiting.

Investigator(s):

Intervention(s):

  • drug : Sapacitabine

Phase: Phase 2

Eligibility

Ages Eligible For Study:

18 Years - N/A

Inclusion Criteria

- Adult patients with advanced CTCL - Have had at least 2 systemic therapies - Must have evaluable disease - Eastern Cooperative Oncology Group performance status 0-2 - Adequate bone marrow, hepatic and renal function - At least 3 weeks from prior therapies - Not receiving topical steroids or have been on a stable dose of topical steroids for at least 2 weeks - Able to swallow capsules - At least 3 weeks from major surgery - Agree to practice effective contraception - Able to understand and willing to sign the informed consent form

External Links

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Contact information

Primary Contact:

Daniel Navi 6507362300

Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305

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