Clinical Trials Directory

High Dose Chemotherapy and Autologous Stem Cell Rescue for Primary Amyloidosis

To evaluate the role of high dose therapy and autologous hematopoietic cell transplant for amyloidosis.

Stanford is not currently accepting new patients for this trial. You may want to check to see if other locations are recruiting.



  • procedure : high dose chemo then auto hematopoietic cell transplant

Phase: Phase 2


Ages Eligible For Study:

18 Years - 75 Years

Inclusion Criteria

1. Primary amyloidosis 2. Age < 75 years. 3. Patients must have their pathology reviewed and the diagnosis confirmed at Stanford University Medical Center. 4. Patients who have undergone bone marrow transplantation previously will not be eligible. 5. Patients must have a Karnofsky performance status greater than 70%. 6. Patients must have a serum creatinine less than 2 mg/dl or creatinine clearance greater than 30 ml/min, bilirubin less than 2 mg/dl, transaminases less than two times normal, left ventricular ejection fraction >45% on echocardiography, cardiac index > 1.8 liters/min/m^2 and pulmonary function tests demonstrating FEV1 and DLCO > 60%. 7. Patients must be HIV negative. 8. Pregnant or lactating women will not be eligible to participate. 9. Patients must provide signed informed consent. 10. Patients with multiple myeloma and amyloid are eligible.

External Links

Explore related trials

Contact information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
BMT Referrals
Not Recruiting

Footer Links: