Research Overview:

Optogenetics is an increasingly powerful tool for controlling neuronal activity using photosensitive opsins and light-emitting diodes. Studies in mice have demonstrated efficacy in elevating aggressive and violent behavior and suppressing anxiety behaviors. Although several years away, potential applications in humans may include the treatment of psychiatric and mood disorders and the amelioration of neurodegenerative diseases. Using the INVEST methodology, this project will explore the translational pathways for this technology and examine the potential ethical, legal and social implications of its possible translation in humans.